## Introduction
This repository holds the analyses and figures for the following manuscript: 

[**"Social dominance mediates behavioral adaptation to chronic stress in a sex-specific manner"**](https://elifesciences.org/articles/58723)

**Authors:**
_Stoyo Karamihalev†, Elena Brivio†, Cornelia Flachskamm, Rainer Stoffel, Mathias V. Schmidt, and Alon Chen_

†Equal contribution authors

The revised manuscript is available online through the journal [eLife](https://elifesciences.org/articles/58723).

An earlier version of the manuscript is available on [bioRxiv](https://www.biorxiv.org/content/10.1101/2020.02.04.933481v1).

## Analyses and Figures
The analyses and figures from this manuscript are available as in html form with embedded code [here](https://stoyokaramihalev.github.io/CMS_Dominance/Figures.html). The datasets used are saved as a single RData file (to be loaded in R via the 'readRDS' function) in the repository under /data/obj.Rds. We will also gladly provide spreadsheets for any specific parts of the dataset upon request. 


## Additional Sources
For additional details on the "Social Box" paradigm, see: 

- [Karamihalev, S., Flachskamm, C., Eren, N., Kimura, M., & Chen, A. (2019). Social context and dominance status contribute to sleep patterns and quality in groups of freely-moving mice. Scientific reports, 9(1), 1-8.](https://www.nature.com/articles/s41598-019-51375-7)
- [Forkosh, O.*†*, Karamihalev, S.*†*, Roeh, S., Alon, U., Anpilov, S., Touma, C., ... & Chen, A. (2019). Identity domains capture individual differences from across the behavioral repertoire. Nature neuroscience, 22(12), 2023-2028.](https://www.nature.com/articles/s41593-019-0516-y)
- [Shemesh, Y.*†*, Sztainberg, Y.*†*, Forkosh, O.*†*, Shlapobersky, T., Chen, A., & Schneidman, E. (2013). High-order social interactions in groups of mice. Elife, 2, e00759.](https://elifesciences.org/articles/00759)
- [Shemesh, Y.*†*, Forkosh, O.*†*, Mahn, M., Anpilov, S., Sztainberg, Y., Manashirov, S., ... & Adler, E. S. (2016). Ucn3 and CRF-R2 in the medial amygdala regulate complex social dynamics. Nature neuroscience, 19(11), 1489.](https://www.nature.com/articles/nn.4346)