GOBPID Pvalue OddsRatio ExpCount Count Size Term enrichment padj GO:0036503 3.90330448688576e-08 18.9881154499151 0.509720749381407 8 103 ERAD pathway 12.3864643227448 1.12805499670998e-05 GO:0034976 2.47298062718606e-07 8.83126565321218 1.49452103216684 11 302 response to endoplasmic reticulum stress 1.98111924915574 3.57345700628386e-05 GO:0030433 3.30213978003889e-06 17.0430194805195 0.410745846588901 6 83 ubiquitin-dependent ERAD pathway 14.3062853824938 0.000318106132143747 GO:0035966 9.48832298377384e-06 8.77356103731815 1.04913396960057 8 212 response to topologically incorrect protein 2.92381630473478 0.000660517424807459 GO:0043413 1.37131645288746e-05 8.31807951987997 1.10357016613644 8 223 macromolecule glycosylation 2.64248225381568 0.000660517424807459 GO:0006486 1.37131645288746e-05 8.31807951987997 1.10357016613644 8 223 protein glycosylation 2.64248225381568 0.000660517424807459 GO:0070085 1.94243053037011e-05 7.90693691121896 1.15800636267232 8 234 glycosylation 2.39988311783184 0.000801946318967088 GO:0006487 3.61256667618273e-05 15.1722643553629 0.376104630611523 5 76 protein N-linked glycosylation 14.2191828254848 0.00117291935650177 GO:0010498 3.65269003754877e-05 5.09354431674795 2.51396253092966 11 508 proteasomal protein catabolic process 0.700159650319301 0.00117291935650177 GO:0006986 4.14447986981727e-05 8.43472981177899 0.940261576528809 7 190 response to unfolded protein 3.18509695290859 0.00119775468237719 GO:0051603 6.95634681519326e-05 4.11575623768488 3.72145634499823 13 752 proteolysis involved in cellular protein catabolic process 0.37760652444545 0.00182762202690077 GO:0009100 7.77291626042243e-05 5.65312757578533 1.81618946624249 9 367 glycoprotein metabolic process 1.09759520079591 0.0018719773327184 GO:0009101 0.000117754799697966 6.04827737546632 1.49452103216684 8 302 glycoprotein biosynthetic process 1.44081399938599 0.00261777977790094 GO:0044257 0.000182876011317504 3.71068776235066 4.09756097560976 13 828 cellular protein catabolic process 0.311468762398189 0.00377508337648276 GO:0035967 0.000197670286898134 7.90340909090909 0.846235418875928 6 171 cellular response to topologically incorrect protein 3.37047296604083 0.00380844752757071 GO:0006511 0.000331952905776437 3.90740104180438 3.2265818310357 11 652 ubiquitin-dependent protein catabolic process 0.425039519741052 0.00572425567245607 GO:0019941 0.000349722013437208 3.88201287610038 3.2463768115942 11 656 modification-dependent protein catabolic process 0.419871914039262 0.00572425567245607 GO:0030163 0.000356528034962662 3.28998993963783 4.98833510074231 14 1008 protein catabolic process 0.226328262786596 0.00572425567245607 GO:0043161 0.000394636689798472 4.49818461876994 2.25662778366914 9 456 proteasome-mediated ubiquitin-dependent protein catabolic process 0.710959141274238 0.0058945814267428 GO:0043632 0.000407929510501232 3.80770322214483 3.30576175326971 11 668 modification-dependent macromolecule catabolic process 0.404922191545054 0.0058945814267428 GO:0030968 0.000541237990133741 8.25147928994083 0.668080593849417 5 135 endoplasmic reticulum unfolded protein response 4.50644718792867 0.00744846567374529 GO:0006457 0.000704192362070767 6.15995260663507 1.07387769529869 6 217 protein folding 2.09297288113997 0.00925052693811143 GO:0006811 0.000836371851397353 2.2689124649094 16.6970661010958 29 3374 ion transport 0.0418446230440318 0.0105091941327754 GO:0034620 0.000898725452233011 7.33877766069547 0.747260516083422 5 151 cellular response to unfolded protein 3.60203499846498 0.0108221523206392 GO:1901137 0.00103892547526494 3.60476956055734 3.1276069282432 10 632 carbohydrate derivative biosynthetic process 0.411242188751803 0.0119210093436479 GO:1901565 0.00107247834925552 2.72571121846484 6.90844821491693 16 1396 organonitrogen compound catabolic process 0.134859319710019 0.0119210093436479 GO:0051234 0.00112253590521983 2.14676481108455 24.0805938494168 37 4866 establishment of localization 0.0256678405855641 0.0120152917262419 GO:0006820 0.00126234937759349 2.27552498189718 13.7921527041357 25 2787 anion transport 0.0528686096926771 0.0130292489330185 GO:0006810 0.00154786270141266 2.09924834523765 23.5312831389183 36 4755 transport 0.0261537083660898 0.0154252524382159 GO:0071702 0.00179916451807698 2.23172103487064 13.3170731707317 24 2691 organic substance transport 0.0544396926540303 0.0173319515241416 GO:0045184 0.00518733921812976 2.1581592096298 10.3478260869565 19 2091 establishment of protein localization 0.0713801331616152 0.0483593881948226 GO:0055085 0.00570876381428929 2.38576779026217 6.67585719335454 14 1349 transmembrane transport 0.126367663277468 0.0495301624068702 GO:1903050 0.00579292088169591 4.69264656048797 1.14810887239307 5 232 regulation of proteolysis involved in cellular protein catabolic process 1.52589922711058 0.0495301624068702 GO:0010243 0.00582707793022003 2.54813558216162 5.29020855425946 12 1069 response to organonitrogen compound 0.172487510511822 0.0495301624068702 GO:1901135 0.00659270578100669 2.5045270660759 5.37433722163309 12 1086 carbohydrate derivative metabolic process 0.167129615498102 0.0544369134488838 GO:0015031 0.00709344649986372 2.1207400194742 9.86284906327324 18 1993 protein transport 0.0744371481822102 0.0569446121794616 GO:0044265 0.007479888576843 2.37540729357863 6.16613644397314 13 1246 cellular macromolecule catabolic process 0.137543187960704 0.0584239945596656 GO:0006886 0.00793157626899863 2.35654151481764 6.21067515022976 13 1255 intracellular protein transport 0.135577530515389 0.0597484124043882 GO:0071705 0.00806293454592089 2.02672413793103 11.5800636267232 20 2340 nitrogen compound transport 0.0599970779457959 0.0597484124043882 GO:0015833 0.00861103072411189 2.07417172990943 10.050901378579 18 2031 peptide transport 0.0716777685898121 0.0622146969817084 GO:1901698 0.00907258023580747 2.39316502463054 5.60197949805585 12 1132 response to nitrogen compound 0.153822622332655 0.0639506265402039 GO:0042886 0.00998848138764986 2.03863097255168 10.1993637327678 18 2061 amide transport 0.0696062665132668 0.0687302647864478 GO:0043687 0.0105117157634569 3.48221544715447 1.85577942735949 6 375 post-translational protein modification 0.700842666666667 0.0706485082706755 GO:1903362 0.0122911394579706 3.87450870297586 1.38069989395546 5 279 regulation of cellular protein catabolic process 1.05509949769402 0.0807304387125797 GO:0006508 0.0134290048021135 2.08082046708656 8.14563449982326 15 1646 proteolysis 0.0909417727574044 0.0862440530624624 GO:0009057 0.0142595784710489 2.11316319677636 7.43796394485684 14 1503 macromolecule catabolic process 0.101798620545558 0.0895873516985465 GO:0051179 0.0161683138457252 1.72113715277778 30.6030399434429 40 6184 localization 0.0171811744701931 0.0990577654551196 GO:0048193 0.0164525008368365 3.14039522058824 2.04878048780488 6 414 Golgi vesicle transport 0.575019253658195 0.0990577654551196 GO:0006812 0.0190568892071049 2.30523357920618 4.74584658890067 10 959 cation transport 0.178605407744642 0.112396754711292 GO:0042176 0.0200579026157027 2.99648711943794 2.14280664545776 6 433 regulation of protein catabolic process 0.525662838886548 0.115934677118762 GO:1901575 0.0243817101194484 1.82598854556055 11.1891127606928 18 2261 organic substance catabolic process 0.0578366591870576 0.138163024010207 GO:0016567 0.0256893917003898 2.28697172947937 4.26581831035702 9 862 protein ubiquitination 0.19895726228864 0.142773734642551 GO:0046903 0.0266693970248493 1.97666040100251 7.26970661010958 13 1469 secretion 0.0989535955469075 0.145423693210971 GO:0032940 0.031774778374882 1.97279578773488 6.67090844821492 12 1348 secretion by cell 0.108475904516197 0.170053906487795 GO:0061024 0.0333026261648333 2.17532181758169 4.46871686108165 9 903 membrane organization 0.181300427147603 0.172808828627905 GO:0051649 0.0335339000257005 1.69542253521127 14.158359844468 21 2861 establishment of localization in cell 0.0421420247293906 0.172808828627905 GO:0033036 0.034200542424032 1.6644112676806 15.9399080947331 23 3221 macromolecule localization 0.0364148231283737 0.172808828627905 GO:0065008 0.0346813566104445 1.63171128710947 18.6468716861082 26 3768 regulation of biological quality 0.0300803841490076 0.172808828627905 GO:0001501 0.0366948318358963 2.58278397565923 2.46942382467303 6 499 skeletal system development 0.395805639334782 0.179742481365662 GO:0140352 0.0385932067503533 1.909432638332 6.86885825379993 12 1388 export from cell 0.102313780531356 0.185890612514202 GO:0046907 0.0403341856247274 1.78001944579485 9.32838458819371 15 1885 intracellular transport 0.069342639433191 0.187919852393174 GO:0009306 0.0409652273383043 2.78734228734229 1.89536938847649 5 383 protein secretion 0.559892016442951 0.187919852393174 GO:0035592 0.0409652273383043 2.78734228734229 1.89536938847649 5 383 establishment of protein localization to extracellular region 0.559892016442951 0.187919852393174 GO:0071692 0.042916610409767 2.74994978911428 1.92011311417462 5 388 protein localization to extracellular region 0.545554787968966 0.193795318881604 GO:0034220 0.0461888897914831 1.96203871748336 5.50300459526334 10 1112 ion transmembrane transport 0.132837974224937 0.205362909995979 GO:0032446 0.0478827816110696 2.02240608458811 4.78048780487805 9 966 protein modification by small protein conjugation 0.158423671926237 0.209668543721199 GO:0008104 0.0507545247390499 1.61864467551094 13.9010250972075 20 2809 protein localization 0.0416349776395127 0.218926233575902 GO:0002790 0.0548781783976328 2.55736477634288 2.05867797808413 5 416 peptide secretion 0.474586261094675 0.23323225818994 GO:0030001 0.0640002750702055 2.44096601073345 2.15270413573701 5 435 metal ion transport 0.434033557933677 0.268059123120136 GO:0072594 0.0788782064406146 2.10546875 2.99893955461294 6 606 establishment of protein localization to organelle 0.268372381792635 0.31080046586385 GO:0006605 0.0789203296378387 2.28703392677192 2.29126899964652 5 463 protein targeting 0.383124425639901 0.31080046586385 GO:0010033 0.0789448417773075 1.50728956537686 15.5242135030046 21 3137 response to organic substance 0.0350527484183401 0.31080046586385 GO:0034613 0.0796127399424583 1.59431376016979 10.248851184164 15 2071 cellular protein localization 0.057446408183088 0.31080046586385 GO:0005975 0.0808376009013655 2.09090438741722 3.01873453517144 6 610 carbohydrate metabolic process 0.264864283794679 0.31080046586385 GO:0006464 0.0823107805331918 1.46654024078384 19.2605160834217 25 3892 cellular protein modification process 0.0271097906581503 0.31080046586385 GO:0036211 0.0823107805331918 1.46654024078384 19.2605160834217 25 3892 protein modification process 0.0271097906581503 0.31080046586385 GO:0070727 0.0828084286211643 1.58347986636188 10.3082361258395 15 2083 cellular macromolecule localization 0.0567864262026523 0.31080046586385 GO:0010817 0.0870317826955906 2.21691655801825 2.36055143160127 5 477 regulation of hormone levels 0.360964975893183 0.322463912808022 GO:0033554 0.0905942633668244 1.55868320610687 10.446800989749 15 2111 cellular response to stress 0.0552900026726082 0.327278387149427 GO:0051641 0.0905960933285612 1.45963828583126 17.6026864616472 23 3557 cellular localization 0.0298601458128116 0.327278387149427 GO:0010876 0.0974530256930039 2.1371716218342 2.4446800989749 5 494 lipid localization 0.336548705928634 0.347702770682446 GO:0009056 0.111403805605826 1.45833333333333 13.4506892895016 18 2718 catabolic process 0.0400226110940553 0.392630485610777 GO:0044248 0.117120141315042 1.47155888402179 11.7532697066101 16 2375 cellular catabolic process 0.0465934182825485 0.407803865542737 GO:0070647 0.120183925527049 1.64730719639543 5.77023683280311 9 1166 protein modification by small protein conjugation or removal 0.108736970010798 0.413489934253777 GO:0098655 0.126947135066413 1.82976494169096 3.42453163662071 6 692 cation transmembrane transport 0.20581208860971 0.427698153752321 GO:0043412 0.127273499040483 1.3742184929253 20.1760339342524 25 4077 macromolecule modification 0.0247053154901576 0.427698153752321 GO:1901566 0.141077514345799 1.49011333494092 8.55143160127253 12 1728 organonitrogen compound biosynthetic process 0.0660124099794239 0.468636800527999 GO:0098916 0.145053654550925 1.86686921695898 2.78119476846942 5 562 anterograde trans-synaptic signaling 0.260033434227024 0.470541892934591 GO:0007268 0.145053654550925 1.86686921695898 2.78119476846942 5 562 chemical synaptic transmission 0.260033434227024 0.470541892934591 GO:0044267 0.146535537592087 1.33065381830891 24.3181336161188 29 4914 cellular protein metabolic process 0.0197269303903411 0.470541892934591 GO:0019538 0.14965449545789 1.32242958908364 26.3025804171085 31 5315 protein metabolic process 0.0180254856549162 0.47482296842598 GO:0099537 0.152011949365074 1.83596085892906 2.82573347472605 5 571 trans-synaptic signaling 0.251900834557617 0.47482296842598 GO:0042221 0.15279770264227 1.33831108761729 19.6564156945917 24 3972 response to chemical 0.0249876020360043 0.47482296842598 GO:0099536 0.162310684726016 1.79301182409991 2.89006716154118 5 584 synaptic signaling 0.240810893225746 0.499019020061899 GO:0006950 0.165884662645068 1.32915396693452 17.9688936019795 22 3631 response to stress 0.0274095560574541 0.504638605309734 GO:0031400 0.171244793465931 1.75814863102999 2.94450335807706 5 595 negative regulation of protein modification process 0.231989266294753 0.514978540577386 GO:0009894 0.1728474686367 1.54020398481973 5.42382467302934 8 1096 regulation of catabolic process 0.109395812243593 0.514978540577386 GO:0098662 0.177863671994312 1.73359917674299 2.98409331919406 5 603 inorganic cation transmembrane transport 0.225874497055903 0.52451633884037 GO:0051223 0.182892579872374 1.71561385634233 3.01378579003181 5 609 regulation of protein transport 0.221445692823305 0.533898541243597 GO:1901564 0.190619420133286 1.2686976144423 30.8752209261223 35 6239 organonitrogen compound metabolic process 0.0147696393801833 0.550890124185196 GO:0007267 0.196712999861247 1.42157526517716 7.35878402262284 10 1487 cell-cell signaling 0.0742864973233615 0.562871851088122 GO:0070201 0.202656237193854 1.64985891301681 3.1276069282432 5 632 regulation of establishment of protein localization 0.205621094375901 0.572518768830211 GO:0010564 0.204046481624608 1.56603773584906 3.96394485683987 6 801 regulation of cell cycle process 0.153609486269504 0.572518768830211 GO:0090087 0.208815571200884 1.6307934967241 3.16224814422057 5 639 regulation of peptide transport 0.201140769149762 0.578835315752326 GO:0051345 0.210303488422125 1.54950186799502 4.00353481795687 6 809 positive regulation of hydrolase activity 0.150586495253491 0.578835315752326 GO:0045055 0.220619150141666 1.52332261029412 4.067868504772 6 822 regulated exocytosis 0.145861082991458 0.601499381046617 GO:0098660 0.234976981035622 1.55609699501102 3.30576175326971 5 668 inorganic ion transmembrane transport 0.184055541611388 0.634657453451353 GO:0016192 0.241770127514074 1.29763691548262 10.4764934605868 13 2117 vesicle-mediated transport 0.0476467688855697 0.643113359186167 GO:0044070 0.244241584551935 1.46782544378698 4.21138211382114 6 851 regulation of anion transport 0.136089290128017 0.643113359186167 GO:0033365 0.245029086820432 1.42061160082708 5.08731000353482 7 1028 protein localization to organelle 0.108803691198958 0.643113359186167 GO:0043009 0.247008937265275 1.52469276285844 3.37009544008484 5 681 chordate embryonic development 0.177095529809535 0.643113359186167 GO:0016071 0.251729540930616 1.45136855971897 4.25592082007777 6 860 mRNA metabolic process 0.133255813953488 0.649552119008464 GO:0045087 0.257319865218833 1.49904825887359 3.42453163662071 5 692 innate immune response 0.171510073841425 0.658101248214539 GO:0009792 0.260151227386955 1.49219620958751 3.43937787203959 5 695 embryo development ending in birth or egg hatching 0.170032607007919 0.659506181709036 GO:0030162 0.273465348422255 1.46099213286713 3.50866030399434 5 709 regulation of proteolysis 0.163383935338714 0.687230310382884 GO:0051640 0.278258171537337 1.45014646848215 3.53340402969247 5 714 organelle localization 0.161103657149134 0.693246651502502 GO:0042592 0.293967474327928 1.25381867569629 9.07104984093319 11 1833 homeostatic process 0.0537773718119855 0.726124787015137 GO:0050896 0.301824458455253 1.16788840019548 37.3283845881937 40 7543 response to stimulus 0.0115479154214674 0.733757722503605 GO:0044093 0.302135532795602 1.24361520343601 9.13538352774832 11 1846 positive regulation of molecular function 0.0530226110391828 0.733757722503605 GO:0031329 0.312874309798035 1.33277027027027 4.60728172499116 6 931 regulation of cellular catabolic process 0.113706085068433 0.753505629430268 GO:0009987 0.315693832893732 2.39417775490701 67.6592435489572 69 13672 cellular process 0.00606340824280365 0.754012543027177 GO:0006887 0.319946203887162 1.320538585209 4.64687168610817 6 939 exocytosis 0.111776854583253 0.757905351831065 GO:0010647 0.345967366151454 1.20276318349874 8.52668787557441 10 1723 positive regulation of cell communication 0.0553300755980084 0.808986395408918 GO:0023056 0.350764891479492 1.19718992248062 8.56132909155179 10 1730 positive regulation of signaling 0.0548832236292559 0.808986395408918 GO:0007417 0.351171526762098 1.2694021177686 4.82007776599505 6 974 central nervous system development 0.103887944883185 0.808986395408918 GO:0065009 0.356570098268164 1.15024216030113 14.3464121597738 16 2899 regulation of molecular function 0.0312719793350968 0.808986395408918 GO:0050790 0.357675756316066 1.16459260950641 11.4711912336515 13 2318 regulation of catalytic activity 0.0397418708371517 0.808986395408918 GO:0044419 0.358305393122289 1.17888322545371 9.56592435489572 11 1933 biological process involved in interspecies interaction between organisms 0.0483571609604631 0.808986395408918 GO:0009967 0.373815048557091 1.18193362859722 7.77447861435136 9 1571 positive regulation of signal transduction 0.0598993290630099 0.830336172008916 GO:0019752 0.376380756170131 1.23108057228916 4.95864262990456 6 1002 carboxylic acid metabolic process 0.0981629555260736 0.830336172008916 GO:0032269 0.376380756170131 1.23108057228916 4.95864262990456 6 1002 negative regulation of cellular protein metabolic process 0.0981629555260736 0.830336172008916 GO:0043269 0.389864261937233 1.19104449995374 5.97808412866737 7 1208 regulation of ion transport 0.0787945155914214 0.853566452271668 GO:0051049 0.401670734058215 1.15035860655738 7.96253092965712 9 1609 regulation of transport 0.0571034358087529 0.862513656429357 GO:0043436 0.40167604337864 1.19485473632812 5.09720749381407 6 1030 oxoacid metabolic process 0.0928984824205863 0.862513656429357 GO:0051716 0.402904303176343 1.0909510047087 31.4938140685755 33 6364 cellular response to stimulus 0.0133839842356499 0.862513656429357 GO:0098542 0.4087151144616 1.21046373365042 4.18663838812301 5 846 defense response to other organism 0.114752220154363 0.868519618230901 GO:0051248 0.418836724637805 1.17138063279003 5.19123365146695 6 1049 negative regulation of protein metabolic process 0.0895637135916816 0.883531484819895 GO:1901700 0.43184870819283 1.1179308898013 8.16542948038176 9 1650 response to oxygen-containing compound 0.054300826446281 0.893559401957033 GO:0000165 0.433559821670649 1.17329898738675 4.31035701661364 5 871 MAPK cascade 0.108259374328569 0.893559401957033 GO:0044281 0.433606258704639 1.1089360159507 9.1502297631672 10 1849 small molecule metabolic process 0.0480460839926044 0.893559401957033 GO:0006082 0.435958047321597 1.14874646892655 5.28525980911983 6 1068 organic acid metabolic process 0.086405336026596 0.893559401957033 GO:0051336 0.443177682813156 1.12516469038208 6.29480381760339 7 1272 regulation of hydrolase activity 0.0710649796289704 0.901960213612692 GO:0051726 0.462237350158645 1.10308833678399 6.40862495581478 7 1295 regulation of cell cycle 0.0685630804549723 0.934171987383555 GO:0051240 0.470489581619826 1.09373394966615 6.45811240721103 7 1305 positive regulation of multicellular organismal process 0.0675163312341275 0.944246452000901 GO:0006807 0.476815400501639 1.04951074119897 44.2219865676918 45 8936 nitrogen compound metabolic process 0.00925673885880215 0.944343350864328 GO:0018193 0.477073111509315 1.0863535817594 6.49770236832803 7 1313 peptidyl-amino acid modification 0.0666960948833767 0.944343350864328 GO:0043085 0.482297826807688 1.07290621464102 7.51714386709085 8 1519 positive regulation of catalytic activity 0.0569516430242168 0.94819096562872 GO:0044238 0.491299917649628 1.04223749084582 46.3598444680099 47 9368 primary metabolic process 0.00879702674438702 0.959362677032044 GO:0032880 0.502817205180753 1.07856497824481 4.66171792152704 5 942 regulation of protein localization 0.0925550281507927 0.975262901323743 GO:0043207 0.513050742699207 1.05466710182768 5.71580063626723 6 1155 response to external biotic stimulus 0.073878675437117 0.981931553907754 GO:0051707 0.513050742699207 1.05466710182768 5.71580063626723 6 1155 response to other organism 0.073878675437117 0.981931553907754 GO:0071310 0.519416947879542 1.02293828882416 12.7628137150937 13 2579 cellular response to organic substance 0.0321049861221387 0.987575644323603 GO:0009607 0.549004201333188 1.01416876574307 5.9236479321315 6 1197 response to biotic stimulus 0.0687851625722619 0.999990191991413 GO:0065007 0.552626010198047 1.00598903980013 50.9176387416048 51 10289 biological regulation 0.00791326409783782 0.999990191991413 GO:0032268 0.555253482444767 0.995444061619067 12.045245669848 12 2434 regulation of cellular protein metabolic process 0.0332714644427175 0.999990191991413 GO:0051130 0.558240282720298 1.00402974209651 5.97808412866737 6 1208 positive regulation of cellular component organization 0.0675381562212184 0.999990191991413 GO:0022603 0.576902855496996 0.98767112926405 5.05761753269707 5 1022 regulation of anatomical structure morphogenesis 0.0786321284002436 0.999990191991413 GO:0009628 0.583002419622146 0.977298092532468 6.12654648285613 6 1238 response to abiotic stimulus 0.0643045612679787 0.999990191991413 GO:0016032 0.588421495448848 0.974234503360717 5.1219512195122 5 1035 viral process 0.0766692338210927 0.999990191991413 GO:0031325 0.590050573387751 0.968746324826532 15.3757511488158 15 3107 positive regulation of cellular metabolic process 0.0255235201429044 0.999990191991413 GO:0034622 0.592808579168966 0.969156447417317 5.14669494521032 5 1040 cellular protein-containing complex assembly 0.0759338017751479 0.999990191991413 GO:0009790 0.595429103405753 0.9661330961909 5.1615411806292 5 1043 embryo development 0.0754976104220347 0.999990191991413 GO:0044087 0.595429103405753 0.9661330961909 5.1615411806292 5 1043 regulation of cellular component biogenesis 0.0754976104220347 0.999990191991413 GO:0048584 0.597651918725078 0.96113782051282 10.3428773418169 10 2090 positive regulation of response to stimulus 0.037604450447563 0.999990191991413 GO:0031399 0.59944309529265 0.959121745685073 8.29904559915164 8 1677 regulation of protein modification process 0.0467256853661147 0.999990191991413 GO:0032270 0.603084039513963 0.955661664392906 7.28950159066808 7 1473 positive regulation of cellular protein metabolic process 0.0529937148832873 0.999990191991413 GO:0043170 0.610204870333427 0.963926807058891 41.6189466242488 41 8410 macromolecule metabolic process 0.0095219014790444 0.999990191991413 GO:0051338 0.621976775808187 0.935885442901346 5.31495227995758 5 1074 regulation of transferase activity 0.0712021749910705 0.999990191991413 GO:0071704 0.623944343226581 0.956886939716048 48.656062212796 48 9832 organic substance metabolic process 0.00815622722105663 0.999990191991413 GO:0006952 0.624287618523161 0.933922313084112 6.38388123011665 6 1290 defense response 0.0592248062015504 0.999990191991413 GO:0008152 0.628230753392694 0.954496367563322 50.6553552492047 50 10236 metabolic process 0.00783864990980351 0.999990191991413 GO:0044403 0.630327493833662 0.926498894988237 5.36443973135384 5 1084 biological process involved in symbiotic interaction 0.0698945411963345 0.999990191991413 GO:0048878 0.631984828895104 0.92464242510496 5.37433722163309 5 1086 chemical homeostasis 0.069637339790876 0.999990191991413 GO:0051246 0.637226126540097 0.931074908032502 12.7232237539767 12 2571 regulation of protein metabolic process 0.0298200873489287 0.999990191991413 GO:0023052 0.637692407130969 0.942752250515481 26.9657122658183 26 5449 signaling 0.0143837309412854 0.999990191991413 GO:0007154 0.64994827677883 0.935154295246038 27.0993283845882 26 5476 cell communication 0.0142422395941437 0.999990191991413 GO:0048522 0.652019860927294 0.933295252602183 26.1145281018028 25 5277 positive regulation of cellular process 0.0147467948569471 0.999990191991413 GO:0006955 0.653212382520684 0.90994316084742 8.68999646518204 8 1756 immune response 0.0426160096720129 0.999990191991413 GO:0051247 0.658864385285634 0.901770293609672 7.67550371155885 7 1551 positive regulation of protein metabolic process 0.0477976189733875 0.999990191991413 GO:0080134 0.669044457714214 0.888044084821429 6.68080593849417 6 1350 regulation of response to stress 0.054077366255144 0.999990191991413 GO:0032879 0.669153278231219 0.90627965833597 13.0053022269353 12 2628 regulation of localization 0.0285405503082365 0.999990191991413 GO:0009893 0.675344660187873 0.909013059302077 17.2018381053376 16 3476 positive regulation of metabolic process 0.021751652958773 0.999990191991413 GO:0022402 0.697027122533081 0.859668533236994 6.87875574407918 6 1390 cell cycle process 0.0510097821023757 0.999990191991413 GO:0070887 0.697075234990153 0.889491580310881 15.3510074231177 14 3102 cellular response to chemical stimulus 0.0238988094866938 0.999990191991413 GO:0010646 0.700554824297345 0.889087607307946 16.4248851184164 15 3319 regulation of cell communication 0.0223670430032024 0.999990191991413 GO:0009888 0.706998236780702 0.861223484715235 9.11558854718982 8 1842 tissue development 0.0387295591700944 0.999990191991413 GO:0051173 0.710366518947279 0.876951414681282 14.4404383174267 13 2918 positive regulation of nitrogen compound metabolic process 0.0250786754802622 0.999990191991413 GO:0065003 0.714251202747077 0.848918900484278 8.09614704842701 7 1636 protein-containing complex assembly 0.0429598998093029 0.999990191991413 GO:0023051 0.719940748361226 0.874847125968202 16.627783669141 15 3360 regulation of signaling 0.0218245110544218 0.999990191991413 GO:0044260 0.721860318308578 0.894092315973624 36.9473312124426 35 7466 cellular macromolecule metabolic process 0.0103139231629857 0.999990191991413 GO:0007165 0.724652536446419 0.88489327741081 24.9169317780134 23 5035 signal transduction 0.0149025540185928 0.999990191991413 GO:0048513 0.740735100575314 0.856525157232704 15.8062919759632 14 3194 animal organ development 0.0225418746561826 0.999990191991413 GO:0007049 0.759024061893076 0.813432211192393 9.57582184517497 8 1935 cell cycle 0.0350961814527706 0.999990191991413 GO:0044237 0.763365615787452 0.863902631759775 48.2403676210675 46 9748 cellular metabolic process 0.00795167477722143 0.999990191991413 GO:0033043 0.768592983399426 0.774919808751437 6.31459879816189 5 1276 regulation of organelle organization 0.0504429496565482 0.999990191991413 GO:0048518 0.817364738813481 0.822077362775037 28.2127960410039 25 5701 positive regulation of biological process 0.0126348399565914 0.999990191991413 GO:0009966 0.821851336513502 0.781250365655313 14.6433368681513 12 2959 regulation of signal transduction 0.0225124693327681 0.999990191991413 GO:0007166 0.823001675462061 0.774435390277355 13.5694591728526 11 2742 cell surface receptor signaling pathway 0.02403198270308 0.999990191991413 GO:0001775 0.825590815997017 0.71048951048951 6.82926829268293 5 1380 cell activation 0.0431264440243646 0.999990191991413 GO:0048585 0.825630026600562 0.725834627329193 7.9971721456345 6 1616 negative regulation of response to stimulus 0.0377398661895893 0.999990191991413 GO:0009891 0.828668091564791 0.73514911014911 9.17992223400495 7 1855 positive regulation of biosynthetic process 0.0334150434826832 0.999990191991413 GO:0006996 0.843090797116563 0.780206122488002 19.2506185931425 16 3890 organelle organization 0.0173681114980736 0.999990191991413 GO:0043933 0.849540584134009 0.71242174243754 9.43230823612584 7 1906 protein-containing complex subunit organization 0.0316507543968404 0.999990191991413 GO:0045893 0.851810131096185 0.679146970348088 7.11134676564157 5 1437 positive regulation of transcription, DNA-templated 0.0397729941708568 0.999990191991413 GO:0042981 0.853950364261475 0.676516246453616 7.1360904913397 5 1442 regulation of apoptotic process 0.0394976540903853 0.999990191991413 GO:0043067 0.866272288985195 0.661108489329348 7.28455284552845 5 1472 regulation of programmed cell death 0.0379041011932892 0.999990191991413 GO:0009605 0.867960562653229 0.713777699206506 11.9759632378932 9 2420 response to external stimulus 0.02524315279011 0.999990191991413 GO:0051128 0.874637423892352 0.70634032571182 12.0798868858254 9 2441 regulation of cellular component organization 0.0248106858106957 0.999990191991413 GO:0010557 0.875396922452227 0.667664454702827 8.60586779780841 6 1739 positive regulation of macromolecule biosynthetic process 0.0325899658115532 0.999990191991413 GO:0003008 0.876993308046412 0.64728582454335 7.42311770943796 5 1500 system process 0.0365022222222222 0.999990191991413 GO:0050794 0.879141574726293 0.77431864698912 46.147048427006 42 9325 regulation of cellular process 0.00793383981772312 0.999990191991413 GO:0031324 0.880147796522009 0.700066912010706 12.1689642983386 9 2459 negative regulation of cellular metabolic process 0.0244487843827052 0.999990191991413 GO:0009058 0.88138828291989 0.766590389016018 28.3266171792153 24 5724 biosynthetic process 0.0120321658631061 0.999990191991413 GO:1903508 0.882794255235196 0.639617166420608 7.50229763167197 5 1516 positive regulation of nucleic acid-templated transcription 0.0357357927054253 0.999990191991413 GO:1902680 0.883149145586345 0.639143264143264 7.50724637681159 5 1517 positive regulation of RNA biosynthetic process 0.035688694466449 0.999990191991413 GO:0045935 0.88626179498024 0.653859773371105 8.76422764227642 6 1771 positive regulation of nucleobase-containing compound metabolic process 0.0314228770762785 0.999990191991413 GO:0051172 0.891516029086084 0.675632798319208 11.2089077412513 8 2265 negative regulation of nitrogen compound metabolic process 0.0256144711001954 0.999990191991413 GO:0007399 0.893515880312191 0.673144876325088 11.2435489572287 8 2272 nervous system development 0.0254568785955168 0.999990191991413 GO:0010604 0.895039226491592 0.707697972621729 15.8161894662425 12 3196 positive regulation of macromolecule metabolic process 0.0192974321782077 0.999990191991413 GO:0042127 0.899785871825513 0.616221806362651 7.75468363379286 5 1567 regulation of cell population proliferation 0.0334475128986528 0.999990191991413 GO:0010605 0.899955075673151 0.686053556282564 13.6634853305055 10 2761 negative regulation of macromolecule metabolic process 0.0215476049770166 0.999990191991413 GO:0009892 0.902465757561054 0.691495937080028 14.8462354188759 11 3000 negative regulation of metabolic process 0.0200762222222222 0.999990191991413 GO:0031328 0.904252230178945 0.629677220394737 9.05620360551432 6 1830 positive regulation of cellular biosynthetic process 0.0294293648660754 0.999990191991413 GO:0048731 0.908964083552917 0.718283865644745 21.5864262990456 17 4362 system development 0.0146760579310165 0.999990191991413 GO:0010941 0.909348085517078 0.602306727149889 7.91304347826087 5 1599 regulation of cell death 0.0321221714165475 0.999990191991413 GO:0007275 0.909810590859624 0.724673715479077 23.7440791799222 19 4798 multicellular organism development 0.0135570417088821 0.999990191991413 GO:0006793 0.909944913939777 0.682196376775004 15.0045952633439 11 3032 phosphorus metabolic process 0.0196546859879839 0.999990191991413 GO:1901576 0.911461463069735 0.73360810565764 27.9851537645811 23 5655 organic substance biosynthetic process 0.0118139311626918 0.999990191991413 GO:0051254 0.911893278955136 0.598493209846922 7.9575821845175 5 1608 positive regulation of RNA metabolic process 0.0317636011484864 0.999990191991413 GO:0006915 0.911920594110922 0.618739875809935 9.19476846942382 6 1858 apoptotic process 0.0285490492340457 0.999990191991413 GO:0016310 0.917746134741348 0.626920455141314 10.5210321668434 7 2126 phosphorylation 0.0254391934645995 0.999990191991413 GO:0032501 0.925516055318436 0.720880037726267 30.4397313538353 25 6151 multicellular organismal process 0.0108537639724866 0.999990191991413 GO:0048583 0.925627519554298 0.682613305062285 18.740897843761 14 3787 regulation of response to stimulus 0.0160350103257227 0.999990191991413 GO:0012501 0.929296352723369 0.592077053014553 9.55107811947685 6 1930 programmed cell death 0.0264586968777685 0.999990191991413 GO:0044249 0.930257281269631 0.708431301621752 27.4704842700601 22 5551 cellular biosynthetic process 0.0117276783067321 0.999990191991413 GO:0016043 0.931119658390061 0.711836925481489 29.5786496995405 24 5977 cellular component organization 0.0110351069988914 0.999990191991413 GO:0002376 0.939945835277906 0.619312540862532 13.445740544362 9 2717 immune system process 0.0200260386998856 0.999990191991413 GO:0048856 0.941852970037399 0.68645310690853 25.7433722163309 20 5202 anatomical structure development 0.0121400679743292 0.999990191991413 GO:0009059 0.942546010960665 0.673874637834782 22.5464828561329 17 4556 macromolecule biosynthetic process 0.0134528193099472 0.999990191991413 GO:0035556 0.942953784814377 0.614248944589442 13.5348179568752 9 2735 intracellular signal transduction 0.0197633092587456 0.999990191991413 GO:0080090 0.94645808325711 0.682525063810752 26.9706610109579 21 5450 regulation of primary metabolic process 0.0116133658782931 0.999990191991413 GO:0006796 0.947378719093124 0.617630669787139 14.8511841640156 10 3001 phosphate-containing compound metabolic process 0.0182389497847047 0.999990191991413 GO:1902531 0.952004357748954 0.528948387929921 8.86815129020856 5 1792 regulation of intracellular signal transduction 0.0255755988919005 0.999990191991413 GO:0008219 0.955098841219707 0.544938891577928 10.2537999293036 6 2072 cell death 0.0229563885451916 0.999990191991413 GO:0071840 0.955690206940168 0.674851754504042 30.4892188052315 24 6161 cellular component organization or biogenesis 0.0103858164413167 0.999990191991413 GO:0048523 0.955779334482461 0.651805093770577 23.0562036055143 17 4659 negative regulation of cellular process 0.0128645713192417 0.999990191991413 GO:0050789 0.959007254199086 0.671621065624357 48.3195475433015 42 9764 regulation of biological process 0.00723645002811958 0.999990191991413 GO:0034645 0.959515409959735 0.639813775616245 22.1258395192648 16 4471 cellular macromolecule biosynthetic process 0.013147478261583 0.999990191991413 GO:0008283 0.959629143455751 0.512457602277962 9.11558854718982 5 1842 cell population proliferation 0.024205974481309 0.999990191991413 GO:0022607 0.963285619026024 0.574768353528154 14.2721809826794 9 2884 cellular component assembly 0.0177739443406734 0.999990191991413 GO:0050793 0.963696234451415 0.544607500582343 11.8373983739837 7 2392 regulation of developmental process 0.0200959021711167 0.999990191991413 GO:0032502 0.964578500852795 0.650137952176579 27.7773064687169 21 5613 developmental process 0.0109486614975181 0.999990191991413 GO:0031323 0.969399115192227 0.639631662829821 28.0494874513963 21 5668 regulation of cellular metabolic process 0.0107372095768242 0.999990191991413 GO:0051171 0.970314804133457 0.630440163823754 25.966065747614 19 5247 regulation of nitrogen compound metabolic process 0.0113360901520173 0.999990191991413 GO:0051239 0.972659739281165 0.521786051531094 12.2629904559915 7 2478 regulation of multicellular organismal process 0.0187252340369261 0.999990191991413 GO:0048519 0.975147486576755 0.614058094054152 25.1990102509721 18 5092 negative regulation of biological process 0.0114032208001214 0.999990191991413 GO:0048468 0.978105220804118 0.462534973745736 9.95687522092612 5 2012 cell development 0.0202883099020193 0.999990191991413 GO:0044085 0.982812062501284 0.519545217569895 15.4499823259102 9 3122 cellular component biogenesis 0.0151673088548094 0.999990191991413 GO:0009653 0.98511202223779 0.479704487260211 13.1339696005656 7 2654 anatomical structure morphogenesis 0.0163240539510679 0.999990191991413 GO:0030154 0.98803282907958 0.520687466030902 18.4192294096854 11 3722 cell differentiation 0.0130428279677223 0.999990191991413 GO:0019222 0.988353079038545 0.582997040624159 30.7663485330505 22 6217 regulation of metabolic process 0.00934959426369591 0.999990191991413 GO:0048869 0.990733562082438 0.506496354611897 18.7953340402969 11 3798 cellular developmental process 0.0125260627458092 0.999990191991413 GO:0006725 0.994832206508827 0.522154663435118 26.5896076352068 17 5373 cellular aromatic compound metabolic process 0.00967268531031885 0.999990191991413 GO:0006139 0.995524944564668 0.510039815530921 25.6740897843761 16 5188 nucleobase-containing compound metabolic process 0.0097645417424351 0.999990191991413 GO:0034641 0.995959323994227 0.520591408084269 29.1481088723931 19 5890 cellular nitrogen compound metabolic process 0.00899611150665425 0.999990191991413 GO:0046483 0.99744411117522 0.486283994634529 26.4510427712973 16 5345 heterocycle metabolic process 0.00919933389396383 0.999990191991413 GO:1901360 0.997584753898405 0.489624504255528 27.6535878402262 17 5588 organic cyclic compound metabolic process 0.00894268524074238 0.999990191991413 GO:0090304 0.997638637570077 0.4621228409661 23.0809473312124 13 4664 nucleic acid metabolic process 0.00981653201486368 0.999990191991413 GO:0060255 0.998341324253723 0.475194267770179 28.1534110993284 17 5689 regulation of macromolecule metabolic process 0.0086279748866057 0.999990191991413 GO:0006355 0.999134951169619 0.333974878444084 15.2965712265818 6 3091 regulation of transcription, DNA-templated 0.0103153759032208 0.999990191991413 GO:0019219 0.999157362008486 0.36881013016412 18.0926122304701 8 3656 regulation of nucleobase-containing compound metabolic process 0.00983126565126 0.999990191991413 GO:0016070 0.999219432867778 0.393064503300724 20.7896783315659 10 4201 RNA metabolic process 0.00930735877998239 0.999990191991413 GO:1903506 0.999300677680629 0.32742180019151 15.5341109932838 6 3139 regulation of nucleic acid-templated transcription 0.0100023129257638 0.999990191991413 GO:2001141 0.99930996256209 0.327018893494898 15.5489572287027 6 3142 regulation of RNA biosynthetic process 0.00998322151050165 0.999990191991413 GO:0034654 0.999472961133011 0.354366472906489 18.6320254506893 8 3765 nucleobase-containing compound biosynthetic process 0.00927025849677871 0.999990191991413 GO:0006351 0.999591158339545 0.31200991697417 16.1230116648993 6 3258 transcription, DNA-templated 0.00928497863878347 0.999990191991413 GO:0019438 0.999595005751353 0.346767855180982 18.9289501590668 8 3825 aromatic compound biosynthetic process 0.00898170789012773 0.999990191991413 GO:0018130 0.999596792084868 0.34664323493131 18.9338989042064 8 3826 heterocycle biosynthetic process 0.00897701341332818 0.999990191991413 GO:2000112 0.99960296493393 0.330042313117066 17.5779427359491 7 3552 regulation of cellular macromolecule biosynthetic process 0.00911347369328788 0.999990191991413 GO:0009889 0.999634250575578 0.343918010752688 19.0427712972782 8 3848 regulation of biosynthetic process 0.00887465908255929 0.999990191991413 GO:0097659 0.999658113375218 0.307201458523245 16.3160127253446 6 3297 nucleic acid-templated transcription 0.00906661500252663 0.999990191991413 GO:0032774 0.999675016281694 0.305865763173834 16.3704489218805 6 3308 RNA biosynthetic process 0.00900641733279332 0.999990191991413 GO:0010556 0.999713388592262 0.321260713298314 17.9342523860021 7 3624 regulation of macromolecule biosynthetic process 0.0087549461768246 0.999990191991413 GO:0010467 0.99975840460737 0.38771492321827 25.8621420996819 13 5226 gene expression 0.00781873259039666 0.999990191991413 GO:0044271 0.999769275470178 0.357659067203099 22.1901732060799 10 4484 cellular nitrogen compound biosynthetic process 0.00816959656735695 0.999990191991413 GO:0051252 0.999787284483216 0.295148099027409 16.8207847295864 6 3399 regulation of RNA metabolic process 0.00853062281180774 0.999990191991413 GO:1901362 0.999791735455792 0.329007850953911 19.6613644397314 8 3973 organic cyclic compound biosynthetic process 0.00832500830391197 0.999990191991413 GO:0031326 0.99985424892359 0.304485192074881 18.6567691763874 7 3770 regulation of cellular biosynthetic process 0.00808997460053895 0.999990191991413 GO:0010468 0.999990191991413 0.251992879808064 21.3488865323436 7 4314 regulation of gene expression 0.00617830831425281 0.999990191991413