# 2021Qian_ADNI_FDG

References
Kok Pin Ng, Xing Qian, Kwun Kei Ng, Fang Ji, Pedro Rosa-Neto, Serge Gauthier, Nagaendran Kandiah, Juan Helen Zhou (2022) Stage-dependent differential influence of metabolic and structural networks on memory across Alzheimer's disease continuum eLife 11:e77745
https://doi.org/10.7554/eLife.77745

vc.R contains the main program. run_vc.R contains an example used in the paper which calls vc.R.

Fortran code and its R-language wrapper for computing the SSS estimator could be found in the following reference.Fortran 90 codes need to be pre-compiled.
Daye ZJ, Xie J, Li H. A Sparse Structured Shrinkage Estimator for Nonparametric Varying-Coefficient Model with an Application in Genomics. J Comput Graph Stat. 2012;21(1):110-133. doi: 10.1198/jcgs.2011.10102. Epub 2012 Apr 10. PMID: 22904608; PMCID: PMC3419598.