\name{a) sbioPN package} \alias{sbioPN-package} \docType{package} \title{Simulation of deterministic and stochastic biochemical reaction networks with spatial effects using Petri Nets} \description{ sbioPN is a package of C functions that can be used to simulate time-dependent evolution of biochemical reaction networks with spatial effects. The model is defined as a place/transition Petri Net, which is close to how biochemical reactions are defined. The model can be either deterministically solved using an explicit Runge Kutta Dormand Prince 45 method, simulated using two highly optimized variants of the stochastic simulation algorithm, or as a deterministic/stochastic hybrid, according to the Haseltine and Rawlings' algorithm. The library has been optimized for speed and flexibility. bioPN has been tested only on 64 bits machines, relying on integers of 64 bits. The behavior on 32 bits architectures is untested and not supported. } \details{ \tabular{ll}{ Package: \tab sbioPN\cr Type: \tab Package\cr Version: \tab 1.1.0\cr Date: \tab 2014-03-15\cr License: \tab GPL (>=2)\cr } } \author{ Roberto Bertolusso and Marek Kimmel Maintainer: Roberto Bertolusso }