# clock-connectome

Repository of code for analysis of clock connectome as done in:

Orie T Shafer, Gabrielle J Gutierrez, Kimberly Li, Amber Mildenhall, Daphna Spira, Jonathan Marty, Aurel A Lazar, Maria de la Paz Fernandez (2022) Connectomic analysis of the Drosophila lateral neuron clock cells reveals the synaptic basis of functional pacemaker classes. eLife 11:e79139

https://doi.org/10.7554/eLife.79139

This repository is organized into a series of jupyter notebooks. The first notebook is **clockConnectomeOverview** which establishes the connectivity among the identified clock neurons. The second notebook is **MandEconnectivity** which characterizes the connectivity patterns of the M and E clock neurons separately. The third notebook is **BeyondClock** which further analyzes the M and E cell connectivity and explores the connections made with non-clock neurons. The **SupplementaryInfo** notebook produces the data structures and analyses for the Supplementary Figures of the paper.