https://github.com/MEMOntology/memon
Tip revision: ef80454a07222f97ae9983f6c9d15096eb16a875 authored by MEMOntology on 14 December 2018, 15:51:10 UTC
Update environmentalProcessOntology.owl
Update environmentalProcessOntology.owl
Tip revision: ef80454
ro.owl
<?xml version="1.0"?>
<rdf:RDF xmlns="http://purl.obolibrary.org/obo/ro.owl#"
xml:base="http://purl.obolibrary.org/obo/ro.owl"
xmlns:owl="http://www.w3.org/2002/07/owl#"
xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
xmlns:swrlb="http://www.w3.org/2003/11/swrlb#"
xmlns:swrl="http://www.w3.org/2003/11/swrl#"
xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
xmlns:cito="http://purl.org/spar/cito/"
xmlns:swrla="http://swrl.stanford.edu/ontologies/3.3/swrla.owl#"
xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
xmlns:xml="http://www.w3.org/XML/1998/namespace"
xmlns:obo="http://purl.obolibrary.org/obo/"
xmlns:foaf="http://xmlns.com/foaf/0.1/"
xmlns:dc="http://purl.org/dc/elements/1.1/"
xmlns:subsets="http://purl.obolibrary.org/obo/ro/subsets#">
<owl:Ontology rdf:about="http://purl.obolibrary.org/obo/ro.owl">
<owl:versionIRI rdf:resource="http://purl.obolibrary.org/obo/ro/releases/2017-10-02/ro.owl"/>
<owl:imports rdf:resource="http://purl.obolibrary.org/obo/ro/annotations.owl"/>
<owl:imports rdf:resource="http://purl.obolibrary.org/obo/ro/pato_import.owl"/>
<owl:imports rdf:resource="http://purl.obolibrary.org/obo/ro/temporal-intervals.owl"/>
<owl:imports rdf:resource="http://purl.obolibrary.org/obo/ro/go_cc_import.owl"/>
<owl:imports rdf:resource="http://purl.obolibrary.org/obo/ro/go_mf_import.owl"/>
<owl:imports rdf:resource="http://purl.obolibrary.org/obo/ro/core.owl"/>
<owl:imports rdf:resource="http://purl.obolibrary.org/obo/ro/rohom.owl"/>
<owl:imports rdf:resource="http://purl.obolibrary.org/obo/ro/go-biotic.owl"/>
<owl:imports rdf:resource="http://purl.obolibrary.org/obo/ro/el-constraints.owl"/>
<dc:description xml:lang="en">The OBO Relations Ontology (RO) is a collection of OWL relations (ObjectProperties) intended for use across a wide variety of biological ontologies.</dc:description>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Includes Ontology(OntologyID(Anonymous-21)) [Axioms: 26 Logical Axioms: 0]</rdfs:comment>
<foaf:homepage rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI"> https://github.com/oborel/obo-relations/</foaf:homepage>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Includes Ontology(OntologyID(Anonymous-21)) [Axioms: 32 Logical Axioms: 0]</rdfs:comment>
<dc:source rdf:resource="http://obofoundry.org/ro"/>
<dc:title xml:lang="en">OBO Relations Ontology</dc:title>
</owl:Ontology>
<!--
///////////////////////////////////////////////////////////////////////////////////////
//
// Annotation properties
//
///////////////////////////////////////////////////////////////////////////////////////
-->
<!-- http://purl.obolibrary.org/obo/IAO_0000232 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000232"/>
<!-- http://purl.obolibrary.org/obo/IAO_0000426 -->
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000426">
<obo:IAO_0000115>An assertion that holds between an OWL Object Property and a string or literal, where the value of the string or literal is a Common Logic sentence of collection of sentences that define the Object Property.</obo:IAO_0000115>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002422"/>
</rdf:Description>
<!-- http://purl.obolibrary.org/obo/IAO_0000589 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000589">
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<rdfs:label xml:lang="en">OBO foundry unique label</rdfs:label>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0001900 -->
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0001900">
<obo:IAO_0000115>An assertion that holds between an OWL Object Property and a temporal interpretation that elucidates how OWL Class Axioms that use this property are to be interpreted in a temporal context.</obo:IAO_0000115>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002422"/>
</rdf:Description>
<!-- http://purl.obolibrary.org/obo/RO_0002161 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002161">
<obo:IAO_0000112>tooth SubClassOf 'never in taxon' value 'Aves'</obo:IAO_0000112>
<obo:IAO_0000115>x never in taxon T if and only if T is a class, and x does not instantiate the class expression "in taxon some T". Note that this is a shortcut relation, and should be used as a hasValue restriction in OWL.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000119 rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/17921072"/>
<obo:IAO_0000119 rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/20973947"/>
<obo:IAO_0000425>?X DisjointWith RO_0002162 some ?Y </obo:IAO_0000425>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">never in taxon</rdfs:label>
<rdfs:seeAlso rdf:resource="https://github.com/obophenotype/uberon/wiki/Taxon-constraints"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002172"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002171 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002171">
<obo:IAO_0000115>A is mutually_spatially_disjoint_with B if both A and B are classes, and there exists no p such that p is part_of some A and p is part_of some B.</obo:IAO_0000115>
<obo:IAO_0000118>non-overlapping with</obo:IAO_0000118>
<obo:IAO_0000118>shares no parts with</obo:IAO_0000118>
<obo:IAO_0000119 rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/22293552"/>
<obo:IAO_0000425>Class: <http://www.w3.org/2002/07/owl#Nothing> EquivalentTo: (BFO_0000050 some ?X) and (BFO_0000050 some ?Y)</obo:IAO_0000425>
<rdfs:label xml:lang="en">mutually spatially disjoint with</rdfs:label>
<rdfs:seeAlso rdf:resource="http://purl.obolibrary.org/obo/RO_0002163"/>
<foaf:page rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://github.com/obophenotype/uberon/wiki/Part-disjointness-Design-Pattern</foaf:page>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002420"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002172 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002172">
<obo:IAO_0000115>An assertion that holds between an ontology class and an organism taxon class, which is intepreted to yield some relationship between instances of the ontology class and the taxon.</obo:IAO_0000115>
<rdfs:label xml:lang="en">taxonomic class assertion</rdfs:label>
<rdfs:seeAlso rdf:resource="https://github.com/obophenotype/uberon/wiki/Taxon-constraints"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002420"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002173 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002173">
<obo:IAO_0000115>S ambiguous_for_taxon T if the class S does not have a clear referent in taxon T. An example would be the class 'manual digit 1', which encompasses a homology hypotheses that is accepted for some species (e.g. human and mouse), but does not have a clear referent in Aves - the referent is dependent on the hypothesis embraced, and also on the ontogenetic stage. [PHENOSCPAE:asilomar_mtg]</obo:IAO_0000115>
<rdfs:label xml:lang="en">ambiguous for taxon</rdfs:label>
<rdfs:seeAlso rdf:resource="https://github.com/obophenotype/uberon/wiki/Taxon-constraints"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002172"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002174 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002174">
<obo:IAO_0000115>S dubious_for_taxon T if it is probably the case that no instances of S can be found in any instance of T.</obo:IAO_0000115>
<obo:IAO_0000117>https://orcid.org/0000-0002-6601-2165</obo:IAO_0000117>
<obo:IAO_0000119 rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/22293552"/>
<rdfs:comment>This relation lacks a strong logical interpretation, but can be used in place of never_in_taxon where it is desirable to state that the definition of the class is too strict for the taxon under consideration, but placing a never_in_taxon link would result in a chain of inconsistencies that will take ongoing coordinated effort to resolve. Example: metencephalon in teleost</rdfs:comment>
<rdfs:label xml:lang="en">dubious for taxon</rdfs:label>
<rdfs:seeAlso rdf:resource="https://github.com/obophenotype/uberon/wiki/Taxon-constraints"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002172"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002175 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002175">
<obo:IAO_0000115>S present_in_taxon T if some instance of T has some S. This does not means that all instances of T have an S - it may only be certain life stages or sexes that have S</obo:IAO_0000115>
<obo:IAO_0000117>https://orcid.org/0000-0002-6601-2165</obo:IAO_0000117>
<obo:IAO_0000119 rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/22293552"/>
<rdfs:label xml:lang="en">present in taxon</rdfs:label>
<rdfs:seeAlso rdf:resource="https://github.com/obophenotype/uberon/wiki/Taxon-constraints"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002172"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002259 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002259">
<rdfs:label>defined by inverse</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#SubsetProperty"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002416 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002416">
<obo:IAO_0000115>An assertion that involves at least one OWL object that is intended to be expanded into one or more logical axioms. The logical expansion can yield axioms expressed using any formal logical system, including, but not limited to OWL2-DL.</obo:IAO_0000115>
<rdfs:label xml:lang="en">logical macro assertion</rdfs:label>
<foaf:page rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://github.com/oborel/obo-relations/wiki/ShortcutRelations</foaf:page>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002419 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002419">
<obo:IAO_0000115>An assertion that holds between an OWL Annotation Property P and a non-negative integer N, with the interpretation: for any P(i j) it must be the case that | { k : P(i k) } | = N.</obo:IAO_0000115>
<rdfs:label xml:lang="en">annotation property cardinality</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002423"/>
<rdfs:range rdf:resource="http://www.w3.org/2001/XMLSchema#nonNegativeInteger"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002420 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002420">
<obo:IAO_0000115>A logical macro assertion whose domain is an IRI for a class</obo:IAO_0000115>
<obo:IAO_0000116>The domain for this class can be considered to be owl:Class, but we cannot assert this in OWL2-DL</obo:IAO_0000116>
<rdfs:label xml:lang="en">logical macro assertion on a class</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002416"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002421 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002421">
<obo:IAO_0000115>A logical macro assertion whose domain is an IRI for a property</obo:IAO_0000115>
<rdfs:label xml:lang="en">logical macro assertion on a property</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002416"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002422 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002422">
<rdfs:label xml:lang="en">logical macro assertion on an object property</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002421"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002423 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002423">
<rdfs:label xml:lang="en">logical macro assertion on an annotation property</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002421"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002474 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002474">
<obo:IAO_0000115>An assertion that holds between an OWL Object Property and a dispositional interpretation that elucidates how OWL Class Axioms or OWL Individuals that use this property are to be interpreted in a dispositional context. For example, A binds B may be interpreted as A have a mutual disposition that is realized by binding to the other one.</obo:IAO_0000115>
<rdfs:label>dispositional interpretation</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002422"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002475 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002475">
<obo:IAO_0000112>'pectoral appendage skeleton' has no connections with 'pelvic appendage skeleton'</obo:IAO_0000112>
<obo:IAO_0000115>A is has_no_connections_with B if there are no parts of A or B that have a connection with the other.</obo:IAO_0000115>
<obo:IAO_0000118>shares no connection with</obo:IAO_0000118>
<obo:IAO_0000425>Class: <http://www.w3.org/2002/07/owl#Nothing> EquivalentTo: (BFO_0000050 some ?X) and (RO_0002170 some (BFO_0000050 some ?Y))</obo:IAO_0000425>
<rdfs:label>has no connections with</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002420"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002483 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002483">
<rdfs:label>inherited annotation property</rdfs:label>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002484 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002484">
<obo:IAO_0000115>Connects an ontology entity (class, property, etc) to a URL from which curator guidance can be obtained. This assertion is inherited in the same manner as functional annotations (e.g. for GO, over SubClassOf and part_of)</obo:IAO_0000115>
<rdfs:label>curator guidance link</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002483"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002504 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002504">
<obo:IAO_0000112>brain always_present_in_taxon 'Vertebrata'</obo:IAO_0000112>
<obo:IAO_0000112>forelimb always_present_in_taxon Euarchontoglires</obo:IAO_0000112>
<obo:IAO_0000115>S always_present_in_taxon T if every fully formed member of taxon T has part some S, or is an instance of S</obo:IAO_0000115>
<obo:IAO_0000116>This is a very strong relation. Often we will not have enough evidence to know for sure that there are no species within a lineage that lack the structure - loss is common in evolution. However, there are some statements we can make with confidence - no vertebrate lineage could persist without a brain or a heart. All primates are limbed. </obo:IAO_0000116>
<obo:IAO_0000118>never lost in</obo:IAO_0000118>
<rdfs:label>always present in taxon</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002175"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002535 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002535">
<obo:IAO_0000232>This properties were created originally for the annotation of developmental or life cycle stages, such as for example Carnegie Stage 20 in humans. </obo:IAO_0000232>
<rdfs:label>temporal logical macro assertion on a class</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002420"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002536 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002536">
<rdfs:label>measurement property has unit</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002423"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002537 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002537">
<rdfs:label>has start time value</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002535"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002538 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002538">
<rdfs:label>has end time value</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002535"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002539 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002539">
<obo:IAO_0000115>Count of number of days intervening between the start of the stage and the time of fertilization according to a reference model. Note that the first day of development has the value of 0 for this property.</obo:IAO_0000115>
<rdfs:label>start, days post fertilization</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002537"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002540 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002540">
<obo:IAO_0000115>Count of number of days intervening between the end of the stage and the time of fertilization according to a reference model. Note that the first day of development has the value of 1 for this property.</obo:IAO_0000115>
<rdfs:label>end, days post fertilization</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002538"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002541 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002541">
<obo:IAO_0000115>Count of number of years intervening between the start of the stage and the time of birth according to a reference model. Note that the first year of post-birth development has the value of 0 for this property, and the period during which the child is one year old has the value 1.</obo:IAO_0000115>
<rdfs:label>start, years post birth</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002537"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002542 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002542">
<obo:IAO_0000115>Count of number of years intervening between the end of the stage and the time of birth according to a reference model. Note that the first year of post-birth development has the value of 1 for this property, and the period during which the child is one year old has the value 2</obo:IAO_0000115>
<rdfs:label>end, years post birth</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002538"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002543 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002543">
<obo:IAO_0000115>Count of number of months intervening between the start of the stage and the time of birth according to a reference model. Note that the first month of post-birth development has the value of 0 for this property, and the period during which the child is one month old has the value 1.</obo:IAO_0000115>
<rdfs:label>start, months post birth</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002537"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002544 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002544">
<obo:IAO_0000115>Count of number of months intervening between the end of the stage and the time of birth according to a reference model. Note that the first month of post-birth development has the value of 1 for this property, and the period during which the child is one month old has the value 2</obo:IAO_0000115>
<rdfs:label>end, months post birth</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002538"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002545 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002545">
<obo:IAO_0000115>Defines the start and end of a stage with a duration of 1 month, relative to either the time of fertilization or last menstrual period of the mother (to be clarified), counting from one, in terms of a reference model. Thus if month_of_gestation=3, then the stage is 2 month in.</obo:IAO_0000115>
<rdfs:label>month of gestation</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002535"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002546 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002546">
<obo:IAO_0000115>A relationship between a stage class and an anatomical structure or developmental process class, in which the stage is characterized by the appearance of the structure or the occurrence of the biological process</obo:IAO_0000115>
<rdfs:label>has developmental stage marker</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002535"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002547 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002547">
<obo:IAO_0000115>Count of number of days intervening between the start of the stage and the time of coitum.</obo:IAO_0000115>
<obo:IAO_0000232>For mouse staging: assuming that it takes place around midnight during a 7pm to 5am dark cycle (noon of the day on which the vaginal plug is found, the embryos are aged 0.5 days post coitum)</obo:IAO_0000232>
<rdfs:label>start, days post coitum</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002537"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002548 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002548">
<obo:IAO_0000115>Count of number of days intervening between the end of the stage and the time of coitum.</obo:IAO_0000115>
<rdfs:label>end, days post coitum</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002538"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002549 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002549">
<rdfs:label>start, weeks post birth</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002537"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002550 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002550">
<rdfs:label>end, weeks post birth</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002538"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002560 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002560">
<obo:IAO_0000115>If Rel is the relational form of a process Pr, then it follow that: Rel(x,y) <-> exists p : Pr(p), x subject-partner-in p, y object-partner-in p</obo:IAO_0000115>
<rdfs:label>is asymmetric relational form of process class</rdfs:label>
<foaf:page rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://github.com/oborel/obo-relations/wiki/InteractionRelations</foaf:page>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002562"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002561 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002561">
<obo:IAO_0000115>If Rel is the relational form of a process Pr, then it follow that: Rel(x,y) <-> exists p : Pr(p), x partner-in p, y partner-in p</obo:IAO_0000115>
<rdfs:label>is symmetric relational form of process class</rdfs:label>
<foaf:page rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://github.com/oborel/obo-relations/wiki/InteractionRelations</foaf:page>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002562"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002562 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002562">
<obo:IAO_0000115>R is the relational form of a process if and only if either (1) R is the symmetric relational form of a process or (2) R is the asymmetric relational form of a process</obo:IAO_0000115>
<rdfs:label>is relational form of process class</rdfs:label>
<foaf:page rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://github.com/oborel/obo-relations/wiki/InteractionRelations</foaf:page>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002594"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002575 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002575">
<obo:IAO_0000115>relation p is the direct form of relation q iff p is a subPropertyOf q, p does not have the Transitive characteristic, q does have the Transitive characteristic, and for all x, y: x q y -> exists z1, z2, ..., zn such that x p z1 ... z2n y</obo:IAO_0000115>
<obo:IAO_0000116>The general property hierarchy is:
"directly P" SubPropertyOf "P"
Transitive(P)
Where we have an annotation assertion
"directly P" "is direct form of" "P"</obo:IAO_0000116>
<obo:RO_0002423>If we have the annotation P is-direct-form-of Q, and we have inverses P' and Q', then it follows that P' is-direct-form-of Q'</obo:RO_0002423>
<dc:creator>Chris Mungall</dc:creator>
<rdfs:label>is direct form of</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002422"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002579 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002579">
<obo:IAO_0000115>relation p is the indirect form of relation q iff p is a subPropertyOf q, and there exists some p' such that p' is the direct form of q, p' o p' -> p, and forall x,y : x q y -> either (1) x p y or (2) x p' y</obo:IAO_0000115>
<dc:creator>Chris Mungall</dc:creator>
<rdfs:label>is indirect form of</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002422"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002580 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002580">
<rdfs:label>logical macro assertion on an axiom</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002416"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002581 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002581">
<obo:IAO_0000115>If R <- P o Q is a defining property chain axiom, then it also holds that R -> P o Q. Note that this cannot be expressed directly in OWL</obo:IAO_0000115>
<rdfs:label>is a defining property chain axiom</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002580"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002582 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002582">
<obo:IAO_0000115>If R <- P o Q is a defining property chain axiom, then (1) R -> P o Q holds and (2) Q is either reflexive or locally reflexive. A corollary of this is that P SubPropertyOf R.</obo:IAO_0000115>
<rdfs:label>is a defining property chain axiom where second argument is reflexive</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002581"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002594 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002594">
<obo:IAO_0000115>An annotation property that connects an object property to a class, where the object property is derived from or a shortcut property for the class. The exact semantics of this annotation may vary on a case by case basis.</obo:IAO_0000115>
<rdfs:label>is relational form of a class</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002422"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002601 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002601">
<obo:IAO_0000115>A shortcut relationship that holds between two entities based on their identity criteria</obo:IAO_0000115>
<rdfs:label>logical macro assertion involving identity</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002416"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002602 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002602">
<obo:IAO_0000115>A shortcut relationship between two entities x and y1, such that the intent is that the relationship is functional and inverse function, but there is no guarantee that this property holds.</obo:IAO_0000115>
<rdfs:label>in approximate one to one relationship with</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002601"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002603 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002603">
<obo:IAO_0000115>x is approximately equivalent to y if it is the case that x is equivalent, identical or near-equivalent to y</obo:IAO_0000115>
<obo:IAO_0000232>The precise meaning of this property is dependent upon some contexts. It is intended to group multiple possible formalisms. Possibilities include a probabilistic interpretation, for example, Pr(x=y) > 0.95. Other possibilities include reified statements of belief, for example, "Database D states that x=y"</obo:IAO_0000232>
<rdfs:label>is approximately equivalent to</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002602"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002604 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002604">
<obo:IAO_0000112>'anterior end of organism' is-opposite-of 'posterior end of organism'</obo:IAO_0000112>
<obo:IAO_0000112>'increase in temperature' is-opposite-of 'decrease in temperature'</obo:IAO_0000112>
<obo:IAO_0000115>x is the opposite of y if there exists some distance metric M, and there exists no z such as M(x,z) <= M(x,y) or M(y,z) <= M(y,x).</obo:IAO_0000115>
<rdfs:label>is opposite of</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002602"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002605 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002605">
<obo:IAO_0000115>x is indistinguishable from y if there exists some distance metric M, and there exists no z such as M(x,z) <= M(x,y) or M(y,z) <= M(y,x).</obo:IAO_0000115>
<rdfs:label>is indistinguishable from</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002603"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002611 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002611">
<rdfs:label>evidential logical macro assertion on an axiom</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002580"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002612 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002612">
<obo:IAO_0000115>A relationship between a sentence and an instance of a piece of evidence in which the evidence supports the axiom</obo:IAO_0000115>
<obo:IAO_0000232>This annotation property is intended to be used in an OWL Axiom Annotation to connect an OWL Axiom to an instance of an ECO (evidence type ontology class). Because in OWL, all axiom annotations must use an Annotation Property, the value of the annotation cannot be an OWL individual, the convention is to use an IRI of the individual.</obo:IAO_0000232>
<rdfs:label>axiom has evidence</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002611"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002613 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002613">
<obo:IAO_0000115>A relationship between a sentence and an instance of a piece of evidence in which the evidence contradicts the axiom</obo:IAO_0000115>
<obo:IAO_0000232>This annotation property is intended to be used in an OWL Axiom Annotation to connect an OWL Axiom to an instance of an ECO (evidence type ontology class). Because in OWL, all axiom annotations must use an Annotation Property, the value of the annotation cannot be an OWL individual, the convention is to use an IRI of the individual.</obo:IAO_0000232>
<rdfs:label>axiom contradicted by evidence</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002611"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002617 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002617">
<obo:IAO_0000112>In the context of a particular project, the IRI with CURIE NCBIGene:64327 (which in this example denotes a class) is considered to be representative. This means that if we have equivalent classes with IRIs OMIM:605522, ENSEMBL:ENSG00000105983, HGNC:13243 forming an equivalence set, the NCBIGene is considered the representative member IRI. Depending on the policies of the project, the classes may be merged, or the NCBIGene IRI may be chosen as the default in a user interface context.</obo:IAO_0000112>
<obo:IAO_0000115>this property relates an IRI to the xsd boolean value "True" if the IRI is intended to be the representative IRI for a collection of classes that are mutually equivalent.</obo:IAO_0000115>
<obo:IAO_0000232>If it is necessary to make the context explicit, an axiom annotation can be added to the annotation assertion</obo:IAO_0000232>
<rdfs:label>is representative IRI for equivalence set</rdfs:label>
<rdfs:seeAlso>OWLAPI Reasoner documentation for representativeElement, which follows a similar idea, but selects an arbitrary member</rdfs:seeAlso>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002601"/>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/ro/subsets#ro-eco -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/ro/subsets#ro-eco">
<rdfs:label>eco subset</rdfs:label>
<rdfs:subPropertyOf rdf:resource="http://www.geneontology.org/formats/oboInOwl#SubsetProperty"/>
</owl:AnnotationProperty>
<!-- http://purl.org/dc/elements/1.1/description -->
<owl:AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/description"/>
<!-- http://purl.org/spar/cito/citesAsAuthority -->
<owl:AnnotationProperty rdf:about="http://purl.org/spar/cito/citesAsAuthority"/>
<!-- http://swrl.stanford.edu/ontologies/3.3/swrla.owl#isRuleEnabled -->
<owl:AnnotationProperty rdf:about="http://swrl.stanford.edu/ontologies/3.3/swrla.owl#isRuleEnabled"/>
<!-- http://www.geneontology.org/formats/oboInOwl#SubsetProperty -->
<owl:AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#SubsetProperty">
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">subset_property</rdfs:label>
</owl:AnnotationProperty>
<!-- http://www.geneontology.org/formats/oboInOwl#created_by -->
<owl:AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#created_by"/>
<!-- http://www.geneontology.org/formats/oboInOwl#creation_date -->
<owl:AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#creation_date"/>
<!-- http://www.geneontology.org/formats/oboInOwl#inSubset -->
<owl:AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#inSubset">
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">in_subset</rdfs:label>
</owl:AnnotationProperty>
<!-- http://xmlns.com/foaf/0.1/page -->
<owl:AnnotationProperty rdf:about="http://xmlns.com/foaf/0.1/page"/>
<!--
///////////////////////////////////////////////////////////////////////////////////////
//
// Object Properties
//
///////////////////////////////////////////////////////////////////////////////////////
-->
<!-- http://purl.obolibrary.org/obo/BFO_0000050 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/BFO_0000050">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002131"/>
<rdfs:seeAlso rdf:resource="http://ontologydesignpatterns.org/wiki/Community:Parts_and_Collections"/>
<rdfs:seeAlso rdf:resource="http://ontologydesignpatterns.org/wiki/Submissions:PartOf"/>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/BFO_0000051 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/BFO_0000051">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002131"/>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/BFO_0000062 -->
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000062">
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000050"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000062"/>
</owl:propertyChainAxiom>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
</rdf:Description>
<!-- http://purl.obolibrary.org/obo/BFO_0000063 -->
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000063">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002222"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000050"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000063"/>
</owl:propertyChainAxiom>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002092"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000063"/>
</owl:propertyChainAxiom>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
</rdf:Description>
<!-- http://purl.obolibrary.org/obo/R0_0009004 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/R0_0009004">
<obo:IAO_0000112 xml:lang="en">sardine has consumer some homo sapiens</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000428"/>
<obo:IAO_0000115 xml:lang="en">'has consumer' is a relation between a material entity and an organism in which the former can normally be digested or otherwise absorbed by the latter without immediate or persistent ill effect.</obo:IAO_0000115>
<obo:IAO_0000117>Damion Dooley</obo:IAO_0000117>
<rdfs:label xml:lang="en">has consumer</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0000052 -->
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0000052">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002314"/>
</rdf:Description>
<!-- http://purl.obolibrary.org/obo/RO_0000057 -->
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0000057">
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000051"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000055"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0000052"/>
</owl:propertyChainAxiom>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000051"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0000057"/>
</owl:propertyChainAxiom>
</rdf:Description>
<!-- http://purl.obolibrary.org/obo/RO_0000300 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000300">
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A relation that holds between two neurons connected directly via a synapse, or indirectly via a series of synaptically connected neurons.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">David Osumi-Sutherland</obo:IAO_0000117>
<obo:IAO_0000426 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">(forall (?x ?y)
(iff
(neural_circuit_path ?x ?y)
(and
("neuron ; CL_0000540" ?x)
("neuron ; CL_0000540" ?y)
(or
(synapsed_by ?x ?y)
(synapsed_to ?x ?y)))))
(forall (...s ?x ?y ?z)
(iff
(neural_circuit_path ...s ?x ?y ?z)
(and
(neural_circuit_path ...s ?x ?y)
("neuron ; CL_0000540" ?z)
(or
(synapsed_by ?y ?z)
(synapsed_to ?y ?z)))))
(forall (?x ?y)
(iff
(in_neural_circuit_with ?x ?y)
(exists (...s)
(neural_circuit_path ?x ...s ?y)))) </obo:IAO_0000426>
<obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
<cito:citesAsAuthority rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/22402613"/>
<rdfs:label xml:lang="en">in neural circuit with</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0000301 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000301">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000300"/>
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A relation that holds between a neuron that is synapsed_to another neuron or a neuron that is connected indirectly to another by a chain of neurons, each synapsed_to the next.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">David Osumi-Sutherland</obo:IAO_0000117>
<obo:IAO_0000426 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">(forall (?x ?y)
(iff
(upstream_neural_circuit_path ?x ?y)
(and
("neuron ; CL_0000540" ?x)
("neuron ; CL_0000540" ?y)
(synapsed_to ?x ?y))))
(forall (...s ?x ?y ?z)
(iff
(upstream_neural_circuit_path ...s ?x ?y ?z )
(and
(upstream_neural_circuit_path ...s ?x ?y)
("neuron ; CL_0000540" ?z)
(synapsed_to ?y ?z))))
(forall (?x ?y)
(iff
(upstream_in_neural_circuit_with ?x ?y)
(exists (...s)
(upstream_neural_circuit_path ?x ...s ?y))))</obo:IAO_0000426>
<obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
<cito:citesAsAuthority rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/22402613"/>
<rdfs:label xml:lang="en">upstream in neural circuit with</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0000302 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000302">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000300"/>
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">A relation that holds between a neuron that is synapsed_to another neuron or a neuron that is connected indirectly to another by a chain of neurons, each synapsed_to the next.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">David Osumi-Sutherland</obo:IAO_0000117>
<obo:IAO_0000426 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">(forall (?x ?y)
(iff
(downstream_neural_circuit_path ?x ?y)
(and
("neuron ; CL_0000540" ?x)
("neuron ; CL_0000540" ?y)
(synapsed_by ?x ?y))))
(forall (...s ?x ?y ?z)
(iff
(downstream_neural_circuit_path ...s ?x ?y ?z )
(and
(downstream_neural_circuit_path ...s ?x ?y)
("neuron ; CL_0000540" ?z)
(synapsed_by ?y ?z))))
(forall (?x ?y)
(iff
(downstream_in_neural_circuit_with ?x ?y)
(exists (...s)
(downstream_neural_circuit_path ?x ...s ?y))))
</obo:IAO_0000426>
<obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
<cito:citesAsAuthority rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/22402613"/>
<rdfs:label xml:lang="en">downstream in neural circuit with</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0001018 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0001018">
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0001019"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000004"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0001025"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000050"/>
</owl:propertyChainAxiom>
<obo:IAO_0000111 xml:lang="en">contained in</obo:IAO_0000111>
<obo:IAO_0000116>Containment is location not involving parthood, and arises only where some immaterial continuant is involved.</obo:IAO_0000116>
<obo:IAO_0000116 xml:lang="en">Containment obtains in each case between material and immaterial continuants, for instance: lung contained_in thoracic cavity; bladder contained_in pelvic cavity. Hence containment is not a transitive relation. If c part_of c1 at t then we have also, by our definition and by the axioms of mereology applied to spatial regions, c located_in c1 at t. Thus, many examples of instance-level location relations for continuants are in fact cases of instance-level parthood. For material continuants location and parthood coincide. Containment is location not involving parthood, and arises only where some immaterial continuant is involved. To understand this relation, we first define overlap for continuants as follows: c1 overlap c2 at t =def for some c, c part_of c1 at t and c part_of c2 at t. The containment relation on the instance level can then be defined (see definition):</obo:IAO_0000116>
<obo:IAO_0000116 xml:lang="en">Intended meaning:
domain: material entity
range: spatial region or site (immaterial continuant)
</obo:IAO_0000116>
<obo:IAO_0000118 xml:lang="en">contained_in</obo:IAO_0000118>
<obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label xml:lang="en">contained in</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0001019 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0001019">
<obo:IAO_0000111 xml:lang="en">contains</obo:IAO_0000111>
<obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label xml:lang="en">contains</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0001020 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0001020">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0003302"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0001022"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<obo:IAO_0000112>penicillin (CHEBI:17334) is allergic trigger for penicillin allergy (DOID:0060520)</obo:IAO_0000112>
<obo:IAO_0000115>A relation between a material entity and a condition (a phenotype or disease) of a host, in which the material entity is not part of the host, and is considered harmless to non-allergic hosts, and the condition results in pathological processes that include an abnormally strong immune response against the material entity.</obo:IAO_0000115>
<rdfs:label xml:lang="en">is allergic trigger for</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0001021 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0001021">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0003302"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0001023"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<obo:IAO_0000115>A relation between a material entity and a condition (a phenotype or disease) of a host, in which the material entity is part of the host itself, and the condition results in pathological processes that include an abnormally strong immune response against the material entity.</obo:IAO_0000115>
<rdfs:label xml:lang="en">is autoimmune trigger for</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0001022 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0001022">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0003302"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<obo:IAO_0000112>penicillin allergy (DOID:0060520) has allergic trigger penicillin (CHEBI:17334)</obo:IAO_0000112>
<obo:IAO_0000115>A relation between a condition (a phenotype or disease) of a host and a material entity, in which the material entity is not part of the host, and is considered harmless to non-allergic hosts, and the condition results in pathological processes that include an abnormally strong immune response against the material entity.</obo:IAO_0000115>
<rdfs:label xml:lang="en">has allergic trigger</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0001023 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0001023">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0003302"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<obo:IAO_0000115>A relation between a condition (a phenotype or disease) of a host and a material entity, in which the material entity is part of the host itself, and the condition results in pathological processes that include an abnormally strong immune response against the material entity.</obo:IAO_0000115>
<rdfs:label xml:lang="en">has autoimmune trigger</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002000 -->
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002000">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002323"/>
</rdf:Description>
<!-- http://purl.obolibrary.org/obo/RO_0002001 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002001">
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000117>David Osumi-Sutherland</obo:IAO_0000117>
<obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
<rdfs:label xml:lang="en">aligned with</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002002 -->
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002002">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002323"/>
<obo:IAO_0000117>David Osumi-Sutherland</obo:IAO_0000117>
</rdf:Description>
<!-- http://purl.obolibrary.org/obo/RO_0002003 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002003">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000300"/>
<obo:IAO_0000115>A relation that holds between two neurons that are electrically coupled via gap junctions.</obo:IAO_0000115>
<obo:IAO_0000117>David Osumi-Sutherland</obo:IAO_0000117>
<cito:citesAsAuthority rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/22402613"/>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">electrically_synapsed_to</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002004 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002004">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0001018"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">The relationship that holds between a trachea or tracheole and an antomical structure that is contained in (and so provides an oxygen supply to).</obo:IAO_0000115>
<obo:IAO_0000117>David Osumi-Sutherland</obo:IAO_0000117>
<rdfs:label xml:lang="en">tracheates</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002005 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002005">
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002134"/>
<obo:IAO_0000117>David Osumi-Sutherland</obo:IAO_0000117>
<cito:citesAsAuthority rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">http://www.ncbi.nlm.nih.gov/pubmed/22402613</cito:citesAsAuthority>
<rdfs:label xml:lang="en">innervated_by</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002006 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002006">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002131"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002130"/>
<obo:IAO_0000117>David Osumi-Sutherland</obo:IAO_0000117>
<rdfs:label xml:lang="en">has synaptic terminal of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002007 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002007">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<rdfs:domain>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000040"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000053"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0002124"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:domain>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<obo:IAO_0000115>X outer_layer_of Y iff:
. X :continuant that bearer_of some PATO:laminar
. X part_of Y
. exists Z :surface
. X has_boundary Z
. Z boundary_of Y
has_boundary: http://purl.obolibrary.org/obo/RO_0002002
boundary_of: http://purl.obolibrary.org/obo/RO_0002000</obo:IAO_0000115>
<obo:IAO_0000117>David Osumi-Sutherland</obo:IAO_0000117>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:comment>A relationship that applies between a continuant and its outer, bounding layer. Examples include the relationship between a multicellular organism and its integument, between an animal cell and its plasma membrane, and between a membrane bound organelle and its outer/bounding membrane.</rdfs:comment>
<rdfs:label xml:lang="en">bounding layer of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002008 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002008">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002323"/>
<rdfs:domain>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000002"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000053"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0001199"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:domain>
<rdfs:range>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000002"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000053"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0001199"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</rdfs:range>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A relation that holds between two linear structures that are approximately parallel to each other for their entire length and where either the two structures are adjacent to each other or one is part of the other.</obo:IAO_0000115>
<obo:IAO_0000116>Note from NCEAS meeting: consider changing primary label</obo:IAO_0000116>
<obo:IAO_0000117>David Osumi-Sutherland</obo:IAO_0000117>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:comment>Example: if we define region of chromosome as any subdivision of a chromosome along its long axis, then we can define a region of chromosome that contains only gene x as 'chromosome region' that coincident_with some 'gene x', where the term gene X corresponds to a genomic sequence.</rdfs:comment>
<rdfs:label>coincident with</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002009 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002009">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/CL_0000000"/>
<obo:IAO_0000115>A relation that applies between a cell(c) and a gene(g) , where the process of 'transcription, DNA templated (GO_0006351)' is occuring in in cell c and that process has input gene g.</obo:IAO_0000115>
<obo:IAO_0000117>David Osumi-Sutherland</obo:IAO_0000117>
<dc:description>x 'cell expresses' y iff:
cell(x)
AND gene(y)
AND exists some 'transcription, DNA templated (GO_0006351)'(t)
AND t occurs_in x
AND t has_input y</dc:description>
<rdfs:label>cell expresses</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002010 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002010">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002418"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
<obo:IAO_0000115>x 'regulates in other organism' y if and only if: (x is the realization of a function to exert an effect on the frequency, rate or extent of y) AND (the agents of x are produced by organism o1 and the agents of y are produced by organism o2).</obo:IAO_0000115>
<obo:IAO_0000117>David Osumi-Sutherland</obo:IAO_0000117>
<rdfs:label>regulates in other organism</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002011 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002011">
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002211"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002313"/>
</owl:propertyChainAxiom>
<obo:IAO_0000115>A relationship that holds between a process that regulates a transport process and the entity transported by that process.</obo:IAO_0000115>
<obo:IAO_0000117>David Osumi-Sutherland</obo:IAO_0000117>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label>regulates transport of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002012 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002012">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002418"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000003"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000003"/>
<obo:IAO_0000115>A part of relation that applies only between occurents.</obo:IAO_0000115>
<rdfs:label>occurent part of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002013 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002013">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002017"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002334"/>
<obo:IAO_0000115>A 'has regulatory component activity' B if A and B are GO molecular functions (GO_0003674), A has_component B and A is regulated by B.</obo:IAO_0000115>
<oboInOwl:created_by rdf:datatype="http://www.w3.org/2001/XMLSchema#string">dos</oboInOwl:created_by>
<oboInOwl:creation_date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2017-05-24T09:30:46Z</oboInOwl:creation_date>
<rdfs:label>has regulatory component activity</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002014 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002014">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002013"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002335"/>
<obo:IAO_0000115>A relationship that holds between a GO molecular function and a component of that molecular function that negatively regulates the activity of the whole. More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is negatively regulated by B.</obo:IAO_0000115>
<oboInOwl:created_by rdf:datatype="http://www.w3.org/2001/XMLSchema#string">dos</oboInOwl:created_by>
<oboInOwl:creation_date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2017-05-24T09:31:01Z</oboInOwl:creation_date>
<rdfs:comment>By convention GO molecular functions are classified by their effector function. Internal regulatory functions are treated as components. For example, NMDA glutmate receptor activity is a cation channel activity with positive regulatory component 'glutamate binding' and negative regulatory components including 'zinc binding' and 'magnesium binding'.</rdfs:comment>
<rdfs:label>has negative regulatory component activity</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002015 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002015">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002013"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002336"/>
<obo:IAO_0000115>A relationship that holds between a GO molecular function and a component of that molecular function that positively regulates the activity of the whole. More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is positively regulated by B.</obo:IAO_0000115>
<oboInOwl:created_by rdf:datatype="http://www.w3.org/2001/XMLSchema#string">dos</oboInOwl:created_by>
<oboInOwl:creation_date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2017-05-24T09:31:17Z</oboInOwl:creation_date>
<rdfs:comment>By convention GO molecular functions are classified by their effector function and internal regulatory functions are treated as components. So, for example calmodulin has a protein binding activity that has positive regulatory component activity calcium binding activity. Receptor tyrosine kinase activity is a tyrosine kinase activity that has positive regulatory component 'ligand binding'.</rdfs:comment>
<rdfs:label>has positive regulatory component activity</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002016 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002016">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002017"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002336"/>
<oboInOwl:created_by rdf:datatype="http://www.w3.org/2001/XMLSchema#string">dos</oboInOwl:created_by>
<oboInOwl:creation_date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2017-05-24T09:36:08Z</oboInOwl:creation_date>
<rdfs:comment>A has necessary component activity B if A and B are GO molecular functions (GO_0003674), A has_component B and B is necessary for A. For example, ATPase coupled transporter activity has necessary component ATPase activity; transcript factor activity has necessary component DNA binding activity.</rdfs:comment>
<rdfs:label>has necessary component activity</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002017 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002017">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002018"/>
<oboInOwl:created_by rdf:datatype="http://www.w3.org/2001/XMLSchema#string">dos</oboInOwl:created_by>
<oboInOwl:creation_date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2017-05-24T09:44:33Z</oboInOwl:creation_date>
<rdfs:comment>A 'has component activity' B if A is A and B are molecular functions (GO_0003674) and A has_component B.</rdfs:comment>
<rdfs:label>has component activity</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002018 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002018">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002180"/>
<obo:IAO_0000115>w 'has process component' p if p and w are processes, w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type.</obo:IAO_0000115>
<oboInOwl:created_by rdf:datatype="http://www.w3.org/2001/XMLSchema#string">dos</oboInOwl:created_by>
<oboInOwl:creation_date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2017-05-24T09:49:21Z</oboInOwl:creation_date>
<rdfs:label>has component process</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002019 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002019">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002233"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/GO_0004872"/>
<obo:IAO_0000115>A relationship that holds between between a receptor and an chemical entity, typically a small molecule or peptide, that carries information between cells or compartments of a cell and which binds the receptor and regulates its effector function.</obo:IAO_0000115>
<oboInOwl:created_by rdf:datatype="http://www.w3.org/2001/XMLSchema#string">dos</oboInOwl:created_by>
<oboInOwl:creation_date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2017-07-19T17:30:36Z</oboInOwl:creation_date>
<rdfs:label>has ligand</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002020 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002020">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002313"/>
<obo:IAO_0000115>Holds between p and c when p is a transport process or transporter activity and the outcome of this p is to move c from one location to another.</obo:IAO_0000115>
<oboInOwl:created_by rdf:datatype="http://www.w3.org/2001/XMLSchema#string">dos</oboInOwl:created_by>
<oboInOwl:creation_date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2017-07-20T17:11:08Z</oboInOwl:creation_date>
<rdfs:label>transports</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002021 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002021">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002479"/>
<obo:IAO_0000115>A relationship between a process and a barrier, where the process occurs in a region spanning the barrier. For cellular processes the barrier is typically a membrane. Examples include transport across a membrane and membrane depolarization.</obo:IAO_0000115>
<oboInOwl:created_by rdf:datatype="http://www.w3.org/2001/XMLSchema#string">dos</oboInOwl:created_by>
<oboInOwl:creation_date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2017-07-20T17:19:37Z</oboInOwl:creation_date>
<rdfs:label>occurs across</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002022 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002022">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002334"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002578"/>
<oboInOwl:created_by rdf:datatype="http://www.w3.org/2001/XMLSchema#string">dos</oboInOwl:created_by>
<oboInOwl:creation_date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2017-09-17T13:52:24Z</oboInOwl:creation_date>
<rdfs:comment>Process(P2) is directly regulated by process(P1) iff: P1 regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding regulates the kinase activity (P2) of protein B then P1 directly regulates P2.</rdfs:comment>
<rdfs:label>directly regulated by</rdfs:label>
</owl:ObjectProperty>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/RO_0002022"/>
<owl:annotatedProperty rdf:resource="http://www.w3.org/2000/01/rdf-schema#comment"/>
<owl:annotatedTarget>Process(P2) is directly regulated by process(P1) iff: P1 regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding regulates the kinase activity (P2) of protein B then P1 directly regulates P2.</owl:annotatedTarget>
<oboInOwl:hasDbXref>GOC:dos</oboInOwl:hasDbXref>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/RO_0002023 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002023">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002022"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002630"/>
<obo:IAO_0000115>Process(P2) is directly negatively regulated by process(P1) iff: P1 negatively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding negatively regulates the kinase activity (P2) of protein B then P2 directly negatively regulated by P1.</obo:IAO_0000115>
<oboInOwl:created_by rdf:datatype="http://www.w3.org/2001/XMLSchema#string">dos</oboInOwl:created_by>
<oboInOwl:creation_date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2017-09-17T13:52:38Z</oboInOwl:creation_date>
<rdfs:label>directly negatively regulated by</rdfs:label>
</owl:ObjectProperty>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/RO_0002023"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000115"/>
<owl:annotatedTarget>Process(P2) is directly negatively regulated by process(P1) iff: P1 negatively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding negatively regulates the kinase activity (P2) of protein B then P2 directly negatively regulated by P1.</owl:annotatedTarget>
<oboInOwl:hasDbXref>GOC:dos</oboInOwl:hasDbXref>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/RO_0002024 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002024">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002022"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002629"/>
<obo:IAO_0000115>Process(P2) is directly postively regulated by process(P1) iff: P1 positively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding positively regulates the kinase activity (P2) of protein B then P2 is directly postively regulated by P1.</obo:IAO_0000115>
<oboInOwl:created_by rdf:datatype="http://www.w3.org/2001/XMLSchema#string">dos</oboInOwl:created_by>
<oboInOwl:creation_date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2017-09-17T13:52:47Z</oboInOwl:creation_date>
<rdfs:label>directly positively regulated by</rdfs:label>
</owl:ObjectProperty>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/RO_0002024"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000115"/>
<owl:annotatedTarget>Process(P2) is directly postively regulated by process(P1) iff: P1 positively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding positively regulates the kinase activity (P2) of protein B then P2 is directly postively regulated by P1.</owl:annotatedTarget>
<oboInOwl:hasDbXref>GOC:dos</oboInOwl:hasDbXref>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/RO_0002025 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002025">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002017"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002211"/>
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#FunctionalProperty"/>
<obo:IAO_0000115>A 'has effector activity' B if A and B are GO molecular functions (GO_0003674), A 'has component activity' B and B is the effector (output function) of B. Each compound function has only one effector activity.</obo:IAO_0000115>
<oboInOwl:created_by rdf:datatype="http://www.w3.org/2001/XMLSchema#string">dos</oboInOwl:created_by>
<oboInOwl:creation_date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2017-09-22T14:14:36Z</oboInOwl:creation_date>
<rdfs:comment>This relation is designed for constructing compound molecular functions, typically in combination with one or more regulatory component activity relations.</rdfs:comment>
<rdfs:label>has effector activity</rdfs:label>
</owl:ObjectProperty>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/RO_0002025"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000115"/>
<owl:annotatedTarget>A 'has effector activity' B if A and B are GO molecular functions (GO_0003674), A 'has component activity' B and B is the effector (output function) of B. Each compound function has only one effector activity.</owl:annotatedTarget>
<oboInOwl:hasDbXref>GOC:dos</oboInOwl:hasDbXref>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/RO_0002082 -->
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002082">
<obo:IAO_0000117>David Osumi-Sutherland</obo:IAO_0000117>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
</rdf:Description>
<!-- http://purl.obolibrary.org/obo/RO_0002085 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002085">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002088"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002092"/>
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
<obo:IAO_0000117>David Osumi-Sutherland</obo:IAO_0000117>
<obo:IAO_0000118>di</obo:IAO_0000118>
<rdfs:comment>Previously had ID http://purl.obolibrary.org/obo/RO_0002124 in test files in sandpit - but this seems to have been dropped from ro-edit.owl at some point. No re-use under this ID AFAIK, but leaving note here in case we run in to clashes down the line. Official ID now chosen from DOS ID range.</rdfs:comment>
<rdfs:label xml:lang="en">encompasses</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002087 -->
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002087">
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002224"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002230"/>
</owl:propertyChainAxiom>
</rdf:Description>
<!-- http://purl.obolibrary.org/obo/RO_0002088 -->
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002088">
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
</rdf:Description>
<!-- http://purl.obolibrary.org/obo/RO_0002090 -->
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002090">
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002230"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002224"/>
</owl:propertyChainAxiom>
<obo:IAO_0000117>David Osumi-Sutherland</obo:IAO_0000117>
<obo:RO_0002575 rdf:resource="http://purl.obolibrary.org/obo/BFO_0000063"/>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
</rdf:Description>
<!-- http://purl.obolibrary.org/obo/RO_0002092 -->
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002092">
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
</rdf:Description>
<!-- http://purl.obolibrary.org/obo/RO_0002100 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002100">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002131"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/CL_0000540"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002100"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000050"/>
</owl:propertyChainAxiom>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">Relation between a neuron and an anatomical structure that its soma is part of.</obo:IAO_0000115>
<obo:IAO_0000117>David Osumi-Sutherland</obo:IAO_0000117>
<obo:IAO_0000424><http://purl.obolibrary.org/obo/BFO_0000051> some (
<http://purl.obolibrary.org/obo/GO_0043025> and <http://purl.obolibrary.org/obo/BFO_0000050> some ?Y)</obo:IAO_0000424>
<obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
<rdfs:label xml:lang="en">has soma location</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002101 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002101">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002131"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002132"/>
<rdfs:domain>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/CL_0000540"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000540"/>
</owl:Restriction>
</owl:unionOf>
</owl:Class>
</rdfs:domain>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/CARO_0001001"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">relationship between a neuron and a neuron projection bundle (e.g.- tract or nerve bundle) that one or more of its projections travels through.
</obo:IAO_0000115>
<obo:IAO_0000117>David Osumi-Sutherland</obo:IAO_0000117>
<obo:IAO_0000118>fasciculates with</obo:IAO_0000118>
<obo:IAO_0000426 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">(forall (?x ?y)
(iff
(fasciculates_with ?x ?y)
(exists (?nps ?npbs)
(and
("neuron ; CL_0000540" ?x)
("neuron projection bundle ; CARO_0001001" ?y)
("neuron projection segment ; CARO_0001502" ?nps)
("neuron projection bundle segment ; CARO_0001500' " ?npbs)
(part_of ?npbs ?y)
(part_of ?nps ?x)
(part_of ?nps ?npbs)
(forall (?npbss)
(if
(and
("neuron projection bundle subsegment ; CARO_0001501" ?npbss)
(part_of ?npbss ?npbs)
)
(overlaps ?nps ?npbss)
))))))</obo:IAO_0000426>
<obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
<cito:citesAsAuthority rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/22402613"/>
<rdfs:label xml:lang="en">fasciculates with</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002102 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002102">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002113"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002110"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/CL_0000540"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002102"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000050"/>
</owl:propertyChainAxiom>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">Relation between a neuron and some structure its axon forms (chemical) synapses in.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000117>David Osumi-Sutherland</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">David Osumi-Sutherland</obo:IAO_0000117>
<obo:IAO_0000424><http://purl.obolibrary.org/obo/BFO_0000051> some (
<http://purl.obolibrary.org/obo/GO_0030424> and <http://purl.obolibrary.org/obo/BFO_0000051> some (
<http://purl.obolibrary.org/obo/GO_0042734> and <http://purl.obolibrary.org/obo/BFO_0000050> some (
<http://purl.obolibrary.org/obo/GO_0045202> and <http://purl.obolibrary.org/obo/BFO_0000050> some ?Y)))</obo:IAO_0000424>
<obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
<cito:citesAsAuthority rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/22402613"/>
<rdfs:label xml:lang="en">axon synapses in</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002103 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002103">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000301"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002120"/>
<rdfs:range>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/CL_0000540"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000540"/>
</owl:Restriction>
</owl:unionOf>
</owl:Class>
</rdfs:range>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">Relation between an anatomical structure (including cells) and a neuron that chemically synapses to it. </obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">David Osumi-Sutherland</obo:IAO_0000117>
<obo:IAO_0000424><http://purl.obolibrary.org/obo/BFO_0000051> some (<http://purl.obolibrary.org/obo/GO_0045211> that part_of some (<http://purl.obolibrary.org/obo/GO_0045202> that has_part some (<http://purl.obolibrary.org/obo/GO_0042734> that <http://purl.obolibrary.org/obo/BFO_0000050> some Y?)))</obo:IAO_0000424>
<obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
<cito:citesAsAuthority rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/22402613"/>
<rdfs:label xml:lang="en">synapsed by</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002104 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002104">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<obo:IAO_0000112 xml:lang="en">Every B cell[CL_0000236] has plasma membrane part some immunoglobulin complex[GO_0019814]</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115>Holds between a cell c and a protein complex or protein p if and only if that cell has as part a plasma_membrane[GO:0005886], and that plasma membrane has p as part.</obo:IAO_0000115>
<obo:IAO_0000117>Alexander Diehl</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000117>Lindsay Cowell</obo:IAO_0000117>
<obo:IAO_0000119 rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/19243617"/>
<obo:IAO_0000424><http://purl.obolibrary.org/obo/BFO_0000051> some (<http://purl.obolibrary.org/obo/GO_0005886> and <http://purl.obolibrary.org/obo/BFO_0000051> some ?Y)</obo:IAO_0000424>
<obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
<rdfs:label xml:lang="en">has plasma membrane part</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002105 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002105">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002120"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002109"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115>A relation between a motor neuron and a muscle that it synapses to via a type Ib bouton.</obo:IAO_0000115>
<obo:IAO_0000117>David Osumi-Sutherland</obo:IAO_0000117>
<obo:IAO_0000117>Marta Costa</obo:IAO_0000117>
<obo:IAO_0000424>BFO_0000051 some (GO_0061176 that BFO_0000051 some (that BFO_0000051 some (GO_0045202 that BFO_0000051 some ( that BFO_0000050 some ?Y))))</obo:IAO_0000424>
<obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
<cito:citesAsAuthority rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/22402613"/>
<rdfs:comment>Expands to: has_part some ('type Ib terminal button' that has_part some ('pre-synaptic membrane' that part_of some ('synapse' that has_part some ('post-synaptic membrane' that part_of some ?Y))))</rdfs:comment>
<rdfs:label xml:lang="en">synapsed_via_type_Ib_bouton_to</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002106 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002106">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002120"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002112"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115>A relation between a motor neuron and a muscle that it synapses to via a type Is bouton.</obo:IAO_0000115>
<obo:IAO_0000117>David Osumi-Sutherland</obo:IAO_0000117>
<obo:IAO_0000117>Marta Costa</obo:IAO_0000117>
<obo:IAO_0000424>BFO_0000051 some (GO_0061177 that BFO_0000051 some (that BFO_0000051 some (GO_0045202 that BFO_0000051 some ( that BFO_0000050 some ?Y))))</obo:IAO_0000424>
<obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
<cito:citesAsAuthority rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/22402613"/>
<rdfs:comment>Expands to: has_part some ('type Is terminal button' that has_part some ('pre-synaptic membrane' that part_of some ('synapse' that has_part some ('post-synaptic membrane' that part_of some ?Y))))</rdfs:comment>
<rdfs:label xml:lang="en">synapsed_via_type_Is_bouton_to</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002107 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002107">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002120"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002108"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115>A relation between a motor neuron and a muscle that it synapses to via a type II bouton.</obo:IAO_0000115>
<obo:IAO_0000117>David Osumi-Sutherland</obo:IAO_0000117>
<obo:IAO_0000117>Marta Costa</obo:IAO_0000117>
<obo:IAO_0000424>BFO_0000051 some (GO_0061175 that BFO_0000051 some (that BFO_0000051 some (GO_0045202 that BFO_0000051 some ( that BFO_0000050 some ?Y))))</obo:IAO_0000424>
<obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
<rdfs:comment>Expands to: has_part some ('type II terminal button' that has_part some ('pre-synaptic membrane' that part_of some ('synapse' that has_part some ('post-synaptic membrane' that part_of some ?Y))))</rdfs:comment>
<rdfs:label xml:lang="en">synapsed_via_type_II_bouton_to</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002108 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002108">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002103"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115>Relation between a muscle and a motor neuron that synapses to it via a type II bouton.</obo:IAO_0000115>
<obo:IAO_0000117>David Osumi-Sutherland</obo:IAO_0000117>
<obo:IAO_0000117>Marta Costa</obo:IAO_0000117>
<obo:IAO_0000424>BFO_0000051 some (GO_0042734 that BFO_0000050 some (GO_0045202 that BFO_0000051 some (GO_0061174 that BFO_0000051 some GO_0045211 that BFO_0000050 some ?Y)))
</obo:IAO_0000424>
<obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
<cito:citesAsAuthority rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/22402613"/>
<rdfs:comment>Expands to: has_part some ('presynaptic membrane' that part_of some ('synapse' that has_part some ('type II terminal button' that has_part some 'postsynaptic membrane' that part_of some ?Y)))))</rdfs:comment>
<rdfs:label xml:lang="en">synapsed_by_via_type_II_bouton</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002109 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002109">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002103"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115>Relation between a muscle and a motor neuron that synapses to it via a type Ib bouton.</obo:IAO_0000115>
<obo:IAO_0000117>David Osumi-Sutherland</obo:IAO_0000117>
<obo:IAO_0000117>Marta Costa</obo:IAO_0000117>
<obo:IAO_0000424>BFO_0000051 some (GO_0042734 that BFO_0000050 some (GO_0045202 that BFO_0000051 some (GO_0061176 that BFO_0000051 some GO_0045211 that BFO_0000050 some ?Y)))</obo:IAO_0000424>
<obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
<cito:citesAsAuthority rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/22402613"/>
<rdfs:comment>Expands to: has_part some ('presynaptic membrane' that part_of some ('synapse' that has_part some ('type Ib terminal button' that has_part some 'postsynaptic membrane' that part_of some ?Y)))))</rdfs:comment>
<rdfs:label xml:lang="en">synapsed_by_via_type_Ib_bouton</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002110 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002110">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002130"/>
<rdfs:domain>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/CL_0000540"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000540"/>
</owl:Restriction>
</owl:unionOf>
</owl:Class>
</rdfs:domain>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002110"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000050"/>
</owl:propertyChainAxiom>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">Relation between a neuron and some structure (e.g.- a brain region) in which it receives (chemical) synaptic input. </obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">David Osumi-Sutherland</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">synapsed in</obo:IAO_0000118>
<obo:IAO_0000424>http://purl.obolibrary.org/obo/BFO_0000051 some (
http://purl.org/obo/owl/GO#GO_0045211 and http://purl.obolibrary.org/obo/BFO_0000050 some (
http://purl.org/obo/owl/GO#GO_0045202 and http://purl.obolibrary.org/obo/BFO_0000050 some ?Y))</obo:IAO_0000424>
<obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
<cito:citesAsAuthority rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/22402613"/>
<rdfs:label xml:lang="en">has postsynaptic terminal in</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002111 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002111">
<rdfs:subPropertyOf rdf:resource="http://www.w3.org/2002/07/owl#topObjectProperty"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000118>has neurotransmitter</obo:IAO_0000118>
<rdfs:label xml:lang="en">releases neurotransmitter</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002112 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002112">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002103"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115>Relation between a muscle and a motor neuron that synapses to it via a type Is bouton.</obo:IAO_0000115>
<obo:IAO_0000117>David Osumi-Sutherland</obo:IAO_0000117>
<obo:IAO_0000117>Marta Costa</obo:IAO_0000117>
<obo:IAO_0000424>BFO_0000051 some (GO_0042734 that BFO_0000050 some (GO_0045202 that BFO_0000051 some (GO_0061177 that BFO_0000051 some GO_0045211 that BFO_0000050 some ?Y)))</obo:IAO_0000424>
<obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
<cito:citesAsAuthority rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/22402613"/>
<rdfs:comment>Expands to: has_part some ('presynaptic membrane' that part_of some ('synapse' that has_part some ('type Is terminal button' that has_part some 'postsynaptic membrane' that part_of some ?Y)))))</rdfs:comment>
<rdfs:label xml:lang="en">synapsed_by_via_type_Is_bouton</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002113 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002113">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002130"/>
<rdfs:domain>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/CL_0000540"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000540"/>
</owl:Restriction>
</owl:unionOf>
</owl:Class>
</rdfs:domain>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002113"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000050"/>
</owl:propertyChainAxiom>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">Relation between a neuron and some structure (e.g.- a brain region) in which it receives (chemical) synaptic input.</obo:IAO_0000115>
<obo:IAO_0000118 xml:lang="en">synapses in</obo:IAO_0000118>
<obo:IAO_0000424 xml:lang="en"><http://purl.obolibrary.org/obo/BFO_0000051> some (<http://purl.obolibrary.org/obo/GO_0042734> that <http://purl.obolibrary.org/obo/BFO_0000050> some (<http://purl.obolibrary.org/obo/GO_0045202> that <http://purl.obolibrary.org/obo/BFO_0000050> some Y?)</obo:IAO_0000424>
<obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
<cito:citesAsAuthority rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/22402613"/>
<rdfs:label xml:lang="en">has presynaptic terminal in</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002114 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002114">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002120"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002115"/>
<obo:IAO_0000115>A relation between a motor neuron and a muscle that it synapses to via a type III bouton.</obo:IAO_0000115>
<obo:IAO_0000424>BFO_0000051 some (GO_0061177 that BFO_0000051 some (that BFO_0000051 some (GO_0097467 that BFO_0000051 some ( that BFO_0000050 some ?Y))))</obo:IAO_0000424>
<obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
<cito:citesAsAuthority rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/22402613"/>
<rdfs:comment>Expands to: has_part some ('type III terminal button' that has_part some ('pre-synaptic membrane' that part_of some ('synapse' that has_part some ('post-synaptic membrane' that part_of some ?Y))))</rdfs:comment>
<rdfs:label xml:lang="en">synapsed_via_type_III_bouton_to</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002115 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002115">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002103"/>
<obo:IAO_0000115>Relation between a muscle and a motor neuron that synapses to it via a type III bouton.
</obo:IAO_0000115>
<obo:IAO_0000424>BFO_0000051 some (GO_0042734 that BFO_0000050 some (GO_0045202 that BFO_0000051 some (GO_0097467 that BFO_0000051 some GO_0045211 that BFO_0000050 some ?Y)))</obo:IAO_0000424>
<obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
<cito:citesAsAuthority rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/22402613"/>
<rdfs:comment>Expands to: has_part some ('presynaptic membrane' that part_of some ('synapse' that has_part some ('type III terminal button' that has_part some 'postsynaptic membrane' that part_of some ?Y)))))</rdfs:comment>
<rdfs:label xml:lang="en">synapsed_by_via_type_III_bouton</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002120 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002120">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000302"/>
<rdfs:domain>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/CL_0000540"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000540"/>
</owl:Restriction>
</owl:unionOf>
</owl:Class>
</rdfs:domain>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en"> Relation between a neuron and an anatomical structure (including cells) that it chemically synapses to.
</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">David Osumi-Sutherland</obo:IAO_0000117>
<obo:IAO_0000424><http://purl.obolibrary.org/obo/BFO_0000051> some (<http://purl.obolibrary.org/obo/GO_0042734> that part_of some (<http://purl.obolibrary.org/obo/GO_0045202> that <http://purl.obolibrary.org/obo/BFO_0000051> some (<http://purl.obolibrary.org/obo/GO_0045211> that <http://purl.obolibrary.org/obo/BFO_0000050> some Y?)))</obo:IAO_0000424>
<obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
<cito:citesAsAuthority rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/22402613"/>
<rdfs:comment>N1 synapsed_to some N2
Expands to:
N1 SubclassOf (
has_part some (
‘pre-synaptic membrane ; GO:0042734’ that part_of some (
‘synapse ; GO:0045202’ that has_part some (
‘post-synaptic membrane ; GO:0045211’ that part_of some N2))))</rdfs:comment>
<rdfs:label xml:lang="en">synapsed to</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002121 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002121">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002110"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/CL_0000540"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002121"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000050"/>
</owl:propertyChainAxiom>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">Relation between a neuron and some structure (e.g.- a brain region) in which its dendrite receives synaptic input.
</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">David Osumi-Sutherland</obo:IAO_0000117>
<obo:IAO_0000424><http://purl.obolibrary.org/obo/BFO_0000051> some (
<http://purl.obolibrary.org/obo/GO_0030425> and <http://purl.obolibrary.org/obo/BFO_0000051> some (
http://purl.obolibrary.org/obo/GO_0042734 and <http://purl.obolibrary.org/obo/BFO_0000050> some (
<http://purl.obolibrary.org/obo/GO_0045202> and <http://purl.obolibrary.org/obo/BFO_0000050> some ?Y)))</obo:IAO_0000424>
<obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
<cito:citesAsAuthority rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/22402613"/>
<rdfs:label xml:lang="en">dendrite synapsed in</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002130 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002130">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002131"/>
<rdfs:domain>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/CL_0000540"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000540"/>
</owl:Restriction>
</owl:unionOf>
</owl:Class>
</rdfs:domain>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002130"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000050"/>
</owl:propertyChainAxiom>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115>A general relation between a neuron and some structure in which it either chemically synapses to some target or in which it receives (chemical) synaptic input.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">David Osumi-Sutherland</obo:IAO_0000117>
<obo:IAO_0000118>has synapse in</obo:IAO_0000118>
<obo:IAO_0000424><http://purl.obolibrary.org/obo/RO_0002131> some (<http://purl.obolibrary.org/obo/GO_0045202> that <http://purl.obolibrary.org/obo/BFO_0000050> some Y?)</obo:IAO_0000424>
<obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
<cito:citesAsAuthority rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/22402613"/>
<rdfs:label xml:lang="en">has synaptic terminal in</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002131 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002131">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002323"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000050"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000050"/>
</owl:propertyChainAxiom>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000051"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000050"/>
</owl:propertyChainAxiom>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000051"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002131"/>
</owl:propertyChainAxiom>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115>x overlaps y if and only if there exists some z such that x has part z and z part of y</obo:IAO_0000115>
<obo:IAO_0000424>http://purl.obolibrary.org/obo/BFO_0000051 some (http://purl.obolibrary.org/obo/BFO_0000050 some ?Y)</obo:IAO_0000424>
<obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label xml:lang="en">overlaps</rdfs:label>
</owl:ObjectProperty>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/RO_0002131"/>
<owl:annotatedProperty rdf:resource="http://www.w3.org/2002/07/owl#propertyChainAxiom"/>
<owl:annotatedTarget rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000051"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000050"/>
</owl:annotatedTarget>
<obo:RO_0002582 rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</obo:RO_0002582>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/RO_0002132 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002132">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002131"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/CARO_0001001"/>
<rdfs:range>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/CL_0000540"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000540"/>
</owl:Restriction>
</owl:unionOf>
</owl:Class>
</rdfs:range>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">The relation between a neuron projection bundle and a neuron projection that is fasciculated with it.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">David Osumi-Sutherland</obo:IAO_0000117>
<obo:IAO_0000118 xml:lang="en">has fasciculating component</obo:IAO_0000118>
<obo:IAO_0000426 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">(forall (?x ?y)
(iff
(has_fasciculating_neuron_projection ?x ?y)
(exists (?nps ?npbs)
(and
("neuron projection bundle ; CARO_0001001" ?x)
("neuron projection ; GO0043005" ?y)
("neuron projection segment ; CARO_0001502" ?nps)
("neuron projection bundle segment ; CARO_0001500" ?npbs)
(part_of ?nps ?y)
(part_of ?npbs ?x)
(part_of ?nps ?npbs)
(forall (?npbss)
(if
(and
("neuron projection bundle subsegment ; CARO_0001501" ?npbss)
(part_of ?npbss ?npbs)
)
(overlaps ?nps ?npbss)
))))))
</obo:IAO_0000426>
<obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
<cito:citesAsAuthority rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/22402613"/>
<rdfs:label xml:lang="en">has fasciculating neuron projection</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002134 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002134">
<rdfs:subPropertyOf rdf:resource="http://www.w3.org/2002/07/owl#topObjectProperty"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/CARO_0001001"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002134"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000050"/>
</owl:propertyChainAxiom>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">Relation between a 'neuron projection bundle' and a region in which one or more of its component neuron projections either synapses to targets or receives synaptic input.
T innervates some R
Expands_to: T has_fasciculating_neuron_projection that synapse_in some R.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">David Osumi-Sutherland</obo:IAO_0000117>
<obo:IAO_0000424><http://purl.obolibrary.org/obo/RO_0002132> some (<http://purl.obolibrary.org/obo/GO_0043005> that (<http://purl.obolibrary.org/obo/RO_0002131> some (<http://purl.obolibrary.org/obo/GO_0045202> that <http://purl.obolibrary.org/obo/BFO_0000050> some Y?)))</obo:IAO_0000424>
<obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
<cito:citesAsAuthority rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/22402613"/>
<rdfs:label xml:lang="en">innervates</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002150 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002150">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002323"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000004"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000004"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">X continuous_with Y if and only if X and Y share a fiat boundary.</obo:IAO_0000115>
<obo:IAO_0000117>David Osumi-Sutherland</obo:IAO_0000117>
<obo:IAO_0000118>connected to</obo:IAO_0000118>
<obo:IAO_0000232>The label for this relation was previously connected to. I relabeled this to "continuous with". The standard notion of connectedness does not imply shared boundaries - e.g. Glasgow connected_to Edinburgh via M8; my patella connected_to my femur (via patellar-femoral joint)</obo:IAO_0000232>
<obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
<rdfs:label xml:lang="en">continuous with</rdfs:label>
<rdfs:seeAlso>FMA:85972</rdfs:seeAlso>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002151 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002151">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002131"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115>x partially overlaps y iff there exists some z such that z is part of x and z is part of y, and it is also the case that neither x is part of y or y is part of x</obo:IAO_0000115>
<obo:IAO_0000116>We would like to include disjointness axioms with part_of and has_part, however this is not possible in OWL2 as these are non-simple properties and hence cannot appear in a disjointness axiom</obo:IAO_0000116>
<obo:IAO_0000118 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">proper overlaps</obo:IAO_0000118>
<obo:IAO_0000426 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">(forall (?x ?y)
(iff
(proper_overlaps ?x ?y)
(and
(overlaps ?x ?y)
(not (part_of ?x ?y))
(not (part_of ?y ?x)))))</obo:IAO_0000426>
<obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label xml:lang="en">partially overlaps</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002156 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002156">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002320"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002157"/>
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">d derived_by_descent_from a if d is specified by some genetic program that is sequence-inherited-from a genetic program that specifies a.</obo:IAO_0000115>
<obo:IAO_0000118 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">ancestral_stucture_of</obo:IAO_0000118>
<obo:IAO_0000118 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">evolutionarily_descended_from</obo:IAO_0000118>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">derived by descent from</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002157 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002157">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002320"/>
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115>inverse of derived by descent from</obo:IAO_0000115>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/RO_0002259"/>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">has derived by descendant</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002158 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002158">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002320"/>
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#SymmetricProperty"/>
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002156"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002157"/>
</owl:propertyChainAxiom>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">two individual entities d1 and d2 stand in a shares_ancestor_with relation if and only if there exists some a such that d1 derived_by_descent_from a and d2 derived_by_descent_from a.</obo:IAO_0000115>
<obo:IAO_0000232>Consider obsoleting and merging with child relation, 'in homology relationship with'</obo:IAO_0000232>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VBO calls this homologous_to</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">shares ancestor with</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002159 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002159">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002320"/>
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#SymmetricProperty"/>
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">serially homologous to</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002160 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002160">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
<obo:IAO_0000112>lactation SubClassOf 'only in taxon' some 'Mammalia'</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115>x only in taxon y if and only if x is in taxon y, and there is no other organism z such that y!=z a and x is in taxon z.</obo:IAO_0000115>
<obo:IAO_0000116>The original intent was to treat this as a macro that expands to 'in taxon' only ?Y - however, this is not necessary if we instead have supplemental axioms that state that each pair of sibling tax have a disjointness axiom using the 'in taxon' property - e.g.
'in taxon' some Eukaryota DisjointWith 'in taxon' some Eubacteria</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000119 rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/17921072"/>
<obo:IAO_0000119 rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/20973947"/>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">only in taxon</rdfs:label>
<rdfs:seeAlso rdf:resource="https://github.com/obophenotype/uberon/wiki/Taxon-constraints"/>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002162 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002162">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002320"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000004"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000050"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002162"/>
</owl:propertyChainAxiom>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000051"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002162"/>
</owl:propertyChainAxiom>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002202"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002162"/>
</owl:propertyChainAxiom>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002206"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002162"/>
</owl:propertyChainAxiom>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002214"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002162"/>
</owl:propertyChainAxiom>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002215"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002162"/>
</owl:propertyChainAxiom>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002217"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002162"/>
</owl:propertyChainAxiom>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002225"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002162"/>
</owl:propertyChainAxiom>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002254"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002162"/>
</owl:propertyChainAxiom>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002295"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002162"/>
</owl:propertyChainAxiom>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115>x is in taxon y if an only if y is an organism, and the relationship between x and y is one of: part of (reflexive), developmentally preceded by, derives from, secreted by, expressed.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000117>Jennifer Deegan</obo:IAO_0000117>
<obo:IAO_0000119 rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/17921072"/>
<obo:IAO_0000119 rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/20973947"/>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Connects a biological entity to its taxon of origin.</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">in taxon</rdfs:label>
<rdfs:seeAlso rdf:resource="https://github.com/obophenotype/uberon/wiki/Taxon-constraints"/>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002163 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002163">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002323"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115>A is spatially_disjoint_from B if and only if they have no parts in common</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">There are two ways to encode this as a shortcut relation. The other possibility to use an annotation assertion between two classes, and expand this to a disjointness axiom. </obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000119 rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/22293552"/>
<obo:IAO_0000232>Note that it would be possible to use the relation to label the relationship between a near infinite number of structures - between the rings of saturn and my left earlobe. The intent is that this is used for parsiomoniously for disambiguation purposes - for example, between siblings in a jointly exhaustive pairwise disjointness hierarchy</obo:IAO_0000232>
<obo:IAO_0000424>BFO_0000051 exactly 0 (BFO_0000050 some ?Y)</obo:IAO_0000424>
<obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">spatially disjoint from</rdfs:label>
<foaf:page rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://github.com/obophenotype/uberon/wiki/Part-disjointness-Design-Pattern</foaf:page>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002170 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002170">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002323"/>
<rdfs:domain>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/RO_0002577"/>
</owl:Restriction>
</rdfs:domain>
<rdfs:range>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/RO_0002577"/>
</owl:Restriction>
</rdfs:range>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002176"/>
</rdf:Description>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002176"/>
</owl:propertyChainAxiom>
<obo:IAO_0000112>a 'toe distal phalanx bone' that is connected to a 'toe medial phalanx bone' (an interphalangeal joint *connects* these two bones).</obo:IAO_0000112>
<obo:IAO_0000115>a is connected to b if and only if a and b are discrete structure, and there exists some connecting structure c, such that c connects a and b</obo:IAO_0000115>
<obo:IAO_0000119 rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/22293552"/>
<rdfs:label xml:lang="en">connected to</rdfs:label>
<foaf:page rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://github.com/obophenotype/uberon/wiki/Connectivity-Design-Pattern</foaf:page>
<foaf:page rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://github.com/obophenotype/uberon/wiki/Modeling-articulations-Design-Pattern</foaf:page>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002176 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002176">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002323"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000004"/>
<rdfs:range>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/RO_0002577"/>
</owl:Restriction>
</rdfs:range>
<obo:IAO_0000112>The M8 connects Glasgow and Edinburgh</obo:IAO_0000112>
<obo:IAO_0000112>a 'toe distal phalanx bone' that is connected to a 'toe medial phalanx bone' (an interphalangeal joint *connects* these two bones).</obo:IAO_0000112>
<obo:IAO_0000115>c connects a if and only if there exist some b such that a and b are similar parts of the same system, and c connects b, specifically, c connects a with b. When one structure connects two others it unites some aspect of the function or role they play within the system.</obo:IAO_0000115>
<obo:IAO_0000119 rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/22293552"/>
<rdfs:label xml:lang="en">connects</rdfs:label>
<foaf:page rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://github.com/obophenotype/uberon/wiki/Connectivity-Design-Pattern</foaf:page>
<foaf:page rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://github.com/obophenotype/uberon/wiki/Modeling-articulations-Design-Pattern</foaf:page>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002177 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002177">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002323"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002567"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002371"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000050"/>
</owl:propertyChainAxiom>
<obo:IAO_0000115>a is attached to part of b if a is attached to b, or a is attached to some p, where p is part of b.</obo:IAO_0000115>
<rdfs:label xml:lang="en">attached to part of</rdfs:label>
</owl:ObjectProperty>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/RO_0002177"/>
<owl:annotatedProperty rdf:resource="http://www.w3.org/2002/07/owl#propertyChainAxiom"/>
<owl:annotatedTarget rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002371"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000050"/>
</owl:annotatedTarget>
<obo:RO_0002582 rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</obo:RO_0002582>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/RO_0002178 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002178">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002170"/>
<obo:IAO_0000115>Relation between an arterial structure and another structure, where the arterial structure acts as a conduit channeling fluid, substance or energy.</obo:IAO_0000115>
<obo:IAO_0000116>Individual ontologies should provide their own constraints on this abstract relation. For example, in the realm of anatomy this should hold between an artery and an anatomical structure</obo:IAO_0000116>
<obo:IAO_0000119 rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/20064205"/>
<rdfs:label xml:lang="en">supplies</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002179 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002179">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002170"/>
<obo:IAO_0000115>Relation between an collecting structure and another structure, where the collecting structure acts as a conduit channeling fluid, substance or energy away from the other structure.</obo:IAO_0000115>
<obo:IAO_0000116>Individual ontologies should provide their own constraints on this abstract relation. For example, in the realm of anatomy this should hold between a vein and an anatomical structure</obo:IAO_0000116>
<obo:IAO_0000119 rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/20064205"/>
<rdfs:label xml:lang="en">drains</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002180 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002180">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115>w 'has component' p if w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type.</obo:IAO_0000115>
<obo:IAO_0000116>The definition of 'has component' is still under discussion. The challenge is in providing a definition that does not imply transitivity.</obo:IAO_0000116>
<obo:IAO_0000232 xml:lang="en">For use in recording has_part with a cardinality constraint, because OWL does not permit cardinality constraints to be used in combination with transitive object properties. In situations where you would want to say something like 'has part exactly 5 digit, you would instead use has_component exactly 5 digit.</obo:IAO_0000232>
<obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label xml:lang="en">has component</rdfs:label>
<rdfs:seeAlso rdf:resource="http://ontologydesignpatterns.org/wiki/Submissions:Componency"/>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002200 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002200">
<rdfs:subPropertyOf rdf:resource="http://www.w3.org/2002/07/owl#topObjectProperty"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002201"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000002"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115>A relationship that holds between a biological entity and a phenotype. Here a phenotype is construed broadly as any kind of quality of an organism part, a collection of these qualities, or a change in quality or qualities (e.g. abnormally increased temperature). The subject of this relationship can be an organism (where the organism has the phenotype, i.e. the qualities inhere in parts of this organism), a genomic entity such as a gene or genotype (if modifications of the gene or the genotype causes the phenotype), or a condition such as a disease (such that if the condition inheres in an organism, then the organism has the phenotype).</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Chris Mungall</obo:IAO_0000117>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label xml:lang="en">has phenotype</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002201 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002201">
<rdfs:subPropertyOf rdf:resource="http://www.w3.org/2002/07/owl#topObjectProperty"/>
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#FunctionalProperty"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115>inverse of has phenotype</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Chris Mungall</obo:IAO_0000117>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/RO_0002259"/>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label xml:lang="en">phenotype of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002202 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002202">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002258"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002203"/>
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000004"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000004"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115>x develops from y if and only if either (a) x directly develops from y or (b) there exists some z such that x directly develops from z and z develops from y</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">David Osumi-Sutherland</obo:IAO_0000117>
<obo:IAO_0000117>Melissa Haendel</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Terry Meehan</obo:IAO_0000117>
<rdfs:comment>This is the transitive form of the develops from relation</rdfs:comment>
<rdfs:label xml:lang="en">develops from</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002203 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002203">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002286"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002387"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002388"/>
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115>inverse of develops from</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">David Osumi-Sutherland</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Terry Meehan</obo:IAO_0000117>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/RO_0002259"/>
<rdfs:label xml:lang="en">develops into</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002204 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002204">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002330"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002205"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000004"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000002"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002512"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002510"/>
</owl:propertyChainAxiom>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115>definition "x has gene product of y if and only if y is a gene (SO:0000704) that participates in some gene expression process (GO:0010467) where the output of that process is either y or something that is ribosomally translated from x"</obo:IAO_0000115>
<obo:IAO_0000116>We would like to be able to express the rule: if t transcribed from g, and t is a noncoding RNA and has an evolved function, then t has gene product g.</obo:IAO_0000116>
<obo:IAO_0000117 xml:lang="en">Chris Mungall</obo:IAO_0000117>
<rdfs:label xml:lang="en">gene product of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002205 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002205">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002330"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000002"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000004"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002511"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002513"/>
</owl:propertyChainAxiom>
<obo:IAO_0000112>every HOTAIR lncRNA is the gene product of some HOXC gene</obo:IAO_0000112>
<obo:IAO_0000112>every sonic hedgehog protein (PR:000014841) is the gene product of some sonic hedgehog gene</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115>x has gene product y if and only if x is a gene (SO:0000704) that participates in some gene expression process (GO:0010467) where the output of that process is either y or something that is ribosomally translated from y</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Chris Mungall</obo:IAO_0000117>
<rdfs:label xml:lang="en">has gene product</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002206 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002206">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002330"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000002"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000004"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002206"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000050"/>
</owl:propertyChainAxiom>
<obo:IAO_0000112>'neural crest cell' SubClassOf expresses some 'Wnt1 gene'</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115>x expressed in y if and only if there is a gene expression process (GO:0010467) that occurs in y, and one of the following holds: (i) x is a gene, and x is transcribed into a transcript as part of the gene expression process (ii) x is a transcript, and the transcription of x is part of the gene expression process (iii) x is a mature gene product such as a protein, and x was translated or otherwise processes from a transcript that was transcribed as part of this gene expression process</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Chris Mungall</obo:IAO_0000117>
<rdfs:label xml:lang="en">expressed in</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002207 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002207">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002202"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002210"/>
<rdfs:domain>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/CARO_0010000"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/CL_0000000"/>
</owl:unionOf>
</owl:Class>
</rdfs:domain>
<rdfs:range>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/CARO_0010000"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/CL_0000000"/>
</owl:unionOf>
</owl:Class>
</rdfs:range>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115>Candidate definition: x directly_develops from y if and only if there exists some developmental process (GO:0032502) p such that x and y both participates in p, and x is the output of p and y is the input of p, and a substantial portion of the matter of y comes from x, and the start of x is coincident with or after the end of y</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000117>David Osumi-Sutherland</obo:IAO_0000117>
<obo:IAO_0000117>has developmental precursor</obo:IAO_0000117>
<obo:IAO_0000119>FBbt</obo:IAO_0000119>
<obo:RO_0002575 rdf:resource="http://purl.obolibrary.org/obo/RO_0002202"/>
<rdfs:comment>TODO - add child relations from DOS</rdfs:comment>
<rdfs:label xml:lang="en">directly develops from</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002208 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002208">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002444"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002209"/>
<obo:IAO_0000115>A parasite that kills or sterilizes its host</obo:IAO_0000115>
<rdfs:label>parasitoid of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002209 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002209">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002445"/>
<obo:IAO_0000115>inverse of parasitoid of</obo:IAO_0000115>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/RO_0002259"/>
<rdfs:label>has parasitoid</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002210 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002210">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002203"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115>inverse of directly develops from</obo:IAO_0000115>
<obo:IAO_0000118>developmental precursor of</obo:IAO_0000118>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/RO_0002259"/>
<rdfs:label xml:lang="en">directly develops into</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002211 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002211">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002411"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002334"/>
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002230"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002211"/>
</owl:propertyChainAxiom>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002578"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002578"/>
</owl:propertyChainAxiom>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115>process(P1) regulates process(P2) iff: P1 results in the initiation or termination of P2 OR affects the frequency of its initiation or termination OR affects the magnitude or rate of output of P2.</obo:IAO_0000115>
<obo:IAO_0000116>We use 'regulates' here to specifically imply control. However, many colloquial usages of the term correctly correspond to the weaker relation of 'causally upstream of or within' (aka influences). Consider relabeling to make things more explicit</obo:IAO_0000116>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000117>David Hill</obo:IAO_0000117>
<obo:IAO_0000117>Tanya Berardini</obo:IAO_0000117>
<obo:IAO_0000119 rdf:resource="http://purl.obolibrary.org/obo/ro/docs/causal-relations"/>
<obo:IAO_0000119>GO</obo:IAO_0000119>
<obo:IAO_0000232>Regulation precludes parthood; the regulatory process may not be within the regulated process.</obo:IAO_0000232>
<obo:IAO_0000589>regulates (processual)</obo:IAO_0000589>
<obo:IAO_0000600 rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">false</obo:IAO_0000600>
<rdfs:label xml:lang="en">regulates</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002212 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002212">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002211"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002305"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002335"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002230"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002212"/>
</owl:propertyChainAxiom>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115>Process(P1) negatively regulates process(P2) iff: P1 terminates P2, or P1 descreases the the frequency of initiation of P2 or the magnitude or rate of output of P2.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000119 rdf:resource="http://purl.obolibrary.org/obo/ro/docs/causal-relations"/>
<obo:IAO_0000589>negatively regulates (process to process)</obo:IAO_0000589>
<rdfs:label xml:lang="en">negatively regulates</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002213 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002213">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002211"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002304"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002336"/>
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002212"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002212"/>
</owl:propertyChainAxiom>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002230"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002213"/>
</owl:propertyChainAxiom>
<obo:IAO_0000115>Process(P1) postively regulates process(P2) iff: P1 initiates P2, or P1 increases the the frequency of initiation of P2 or the magnitude or rate of output of P2.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000119 rdf:resource="http://purl.obolibrary.org/obo/ro/docs/causal-relations"/>
<obo:IAO_0000589>positively regulates (process to process)</obo:IAO_0000589>
<rdfs:label xml:lang="en">positively regulates</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002214 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002214">
<obo:IAO_0000112>'human p53 protein' SubClassOf some ('has prototype' some ('participates in' some 'DNA repair'))</obo:IAO_0000112>
<obo:IAO_0000112>heart SubClassOf 'has prototype' some ('participates in' some 'blood circulation')</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115>x has prototype y if and only if x is an instance of C and y is a prototypical instance of C. For example, every instance of heart, both normal and abnormal is related by the has prototype relation to some instance of a "canonical" heart, which participates in blood circulation.</obo:IAO_0000115>
<obo:IAO_0000116>Experimental. In future there may be a formalization in which this relation is treated as a shortcut to some modal logic axiom. We may decide to obsolete this and adopt a more specific evolutionary relationship (e.g. evolved from)</obo:IAO_0000116>
<obo:IAO_0000116>This property can be used to make weaker forms of certain relations by chaining an additional property. For example, we may say: retina SubClassOf has_prototype some 'detection of light'. i.e. every retina is related to a prototypical retina instance which is detecting some light. Note that this is very similar to 'capable of', but this relation affords a wider flexibility. E.g. we can make a relation between continuants.</obo:IAO_0000116>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:label xml:lang="en">has prototype</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002215 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002215">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002216"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000004"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002214"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002217"/>
</owl:propertyChainAxiom>
<obo:IAO_0000112>mechanosensory neuron capable of detection of mechanical stimulus involved in sensory perception (GO:0050974)</obo:IAO_0000112>
<obo:IAO_0000112>osteoclast SubClassOf 'capable of' some 'bone resorption'</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115>A relation between a material entity (such as a cell) and a process, in which the material entity has the ability to carry out the process. </obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000118>has function realized in</obo:IAO_0000118>
<obo:IAO_0000119 rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/20123131"/>
<obo:IAO_0000119 rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/21208450"/>
<obo:IAO_0000232>For compatibility with BFO, this relation has a shortcut definition in which the expression "capable of some P" expands to "bearer_of (some realized_by only P)".</obo:IAO_0000232>
<obo:IAO_0000424>RO_0000053 some (RO_0000054 only ?Y)</obo:IAO_0000424>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label xml:lang="en">capable of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002216 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002216">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002328"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002500"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002215"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000050"/>
</owl:propertyChainAxiom>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115>c stands in this relationship to p if and only if there exists some p' such that c is capable_of p', and p' is part_of p.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000118>has function in</obo:IAO_0000118>
<obo:IAO_0000424>RO_0000053 some (RO_0000054 only (BFO_0000050 some ?Y))</obo:IAO_0000424>
<rdfs:label xml:lang="en">capable of part of</rdfs:label>
</owl:ObjectProperty>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/RO_0002216"/>
<owl:annotatedProperty rdf:resource="http://www.w3.org/2002/07/owl#propertyChainAxiom"/>
<owl:annotatedTarget rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002215"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000050"/>
</owl:annotatedTarget>
<obo:RO_0002582 rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</obo:RO_0002582>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/RO_0002217 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002217">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002218"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115>x actively participates in y if and only if x participates in y and x realizes some active role</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000118>agent in</obo:IAO_0000118>
<rdfs:label xml:lang="en">actively participates in</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002218 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002218">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
<obo:IAO_0000112>'heart development' has active participant some Shh protein</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115>x has participant y if and only if x realizes some active role that inheres in y</obo:IAO_0000115>
<obo:IAO_0000116>This may be obsoleted and replaced by the original 'has agent' relation</obo:IAO_0000116>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000118>has agent</obo:IAO_0000118>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label xml:lang="en">has active participant</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002219 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002219">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002220"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002221"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115>x surrounded_by y if and only if (1) x is adjacent to y and for every region r that is adjacent to x, r overlaps y (2) the shared boundary between x and y occupies the majority of the outermost boundary of x</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
<rdfs:label xml:lang="en">surrounded by</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002220 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002220">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002163"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000004"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000004"/>
<obo:IAO_0000112>A caterpillar walking on the surface of a leaf is adjacent_to the leaf, if one of the caterpillar appendages is touching the leaf. In contrast, a butterfly flying close to a flower is not considered adjacent, unless there are any touching parts.</obo:IAO_0000112>
<obo:IAO_0000112>The epidermis layer of a vertebrate is adjacent to the dermis.</obo:IAO_0000112>
<obo:IAO_0000112>The plasma membrane of a cell is adjacent to the cytoplasm, and also to the cell lumen which the cytoplasm occupies.</obo:IAO_0000112>
<obo:IAO_0000112>The skin of the forelimb is adjacent to the skin of the torso if these are considered anatomical subdivisions with a defined border. Otherwise a relation such as continuous_with would be used.</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115>x adjacent to y if and only if x and y share a boundary.</obo:IAO_0000115>
<obo:IAO_0000116>This relation acts as a join point with BSPO</obo:IAO_0000116>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
<rdfs:label xml:lang="en">adjacent to</rdfs:label>
</owl:ObjectProperty>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/RO_0002220"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000112"/>
<owl:annotatedTarget>A caterpillar walking on the surface of a leaf is adjacent_to the leaf, if one of the caterpillar appendages is touching the leaf. In contrast, a butterfly flying close to a flower is not considered adjacent, unless there are any touching parts.</owl:annotatedTarget>
<rdfs:seeAlso rdf:resource="https://github.com/jhpoelen/eol-globi-data/issues/225#issuecomment-218584934"/>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/RO_0002221 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002221">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002220"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115>inverse of surrounded by</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/RO_0002259"/>
<rdfs:label xml:lang="en">surrounds</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002222 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002222">
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000232>Do not use this relation directly. It is ended as a grouping for relations between occurrents involving the relative timing of their starts and ends.</obo:IAO_0000232>
<dc:source rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://docs.google.com/document/d/1kBv1ep_9g3sTR-SD3jqzFqhuwo9TPNF-l-9fUDbO6rM/edit?pli=1</dc:source>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002223 -->
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002223">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
</rdf:Description>
<!-- http://purl.obolibrary.org/obo/RO_0002224 -->
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002224">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
</rdf:Description>
<!-- http://purl.obolibrary.org/obo/RO_0002225 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002225">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002202"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002207"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000050"/>
</owl:propertyChainAxiom>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115>x develops from part of y if and only if there exists some z such that x develops from z and z is part of y</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:label xml:lang="en">develops from part of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002226 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002226">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002258"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/CARO_0000003"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002207"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0001025"/>
</owl:propertyChainAxiom>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115>x develops_in y if x is located in y whilst x is developing</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000119>EHDAA2</obo:IAO_0000119>
<obo:IAO_0000119>Jonathan Bard, EHDAA2</obo:IAO_0000119>
<rdfs:label xml:lang="en">develops in</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002227 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002227">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002444"/>
<obo:IAO_0000115>A sub-relation of parasite-of in which the parasite that cannot complete its life cycle without a host.</obo:IAO_0000115>
<rdfs:label>obligate parasite of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002228 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002228">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002444"/>
<obo:IAO_0000115>A sub-relations of parasite-of in which the parasite that can complete its life cycle independent of a host.</obo:IAO_0000115>
<rdfs:label>facultative parasite of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002229 -->
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002229">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
</rdf:Description>
<!-- http://purl.obolibrary.org/obo/RO_0002230 -->
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002230">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
</rdf:Description>
<!-- http://purl.obolibrary.org/obo/RO_0002231 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002231">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002479"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000004"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002224"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000066"/>
</owl:propertyChainAxiom>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115>x 'has starts location' y if and only if there exists some process z such that x 'starts with' z and z 'occurs in' y</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000118>starts with process that occurs in</obo:IAO_0000118>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label xml:lang="en">has start location</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002232 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002232">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002479"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000004"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002230"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000066"/>
</owl:propertyChainAxiom>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115>x 'has end location' y if and only if there exists some process z such that x 'ends with' z and z 'occurs in' y</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000118>ends with process that occurs in</obo:IAO_0000118>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label xml:lang="en">has end location</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002233 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002233">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002352"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002224"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002233"/>
</owl:propertyChainAxiom>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115>p has input c iff: p is a process, c is a material entity, c is a participant in p, c is present at the start of p, and the state of c is modified during p.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000118>consumes</obo:IAO_0000118>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label xml:lang="en">has input</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002234 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002234">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002353"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002230"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002234"/>
</owl:propertyChainAxiom>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115>p has output c iff c is a participant in p, c is present at the end of p, and c is not present at the beginning of p.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000118>produces</obo:IAO_0000118>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label xml:lang="en">has output</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002235 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002235">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002444"/>
<obo:IAO_0000115>A parasite-of relationship in which the host is a plant and the parasite that attaches to the host stem (PO:0009047)</obo:IAO_0000115>
<rdfs:label>stem parasite of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002236 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002236">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002444"/>
<obo:IAO_0000115>A parasite-of relationship in which the host is a plant and the parasite that attaches to the host root (PO:0009005)</obo:IAO_0000115>
<rdfs:label>root parasite of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002237 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002237">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002444"/>
<obo:IAO_0000115>A sub-relation of parasite-of in which the parasite is a plant, and the parasite is parasitic under natural conditions and is also photosynthetic to some degree. Hemiparasites may just obtain water and mineral nutrients from the host plant. Many obtain at least part of their organic nutrients from the host as well.</obo:IAO_0000115>
<rdfs:label>hemiparasite of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002240 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002240">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002244"/>
<obo:IAO_0000115>A broad relationship between an exposure event or process and any entity (e.g., an organism, organism population, or an organism part) that interacts with an exposure stimulus during the exposure event.</obo:IAO_0000115>
<obo:IAO_0000119>ExO:0000001</obo:IAO_0000119>
<rdfs:label>has exposure receptor</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002241 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002241">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002309"/>
<obo:IAO_0000115>A broad relationship between an exposure event or process and any agent, stimulus, activity, or event that causes stress or tension on an organism and interacts with an exposure receptor during an exposure event.</obo:IAO_0000115>
<obo:IAO_0000119>ExO:0000000</obo:IAO_0000119>
<rdfs:label>has exposure stressor</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002242 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002242">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002244"/>
<obo:IAO_0000115>A broad relationship between an exposure event or process and a process by which the exposure stressor comes into contact with the exposure receptor</obo:IAO_0000115>
<obo:IAO_0000119>ExO:0000055</obo:IAO_0000119>
<rdfs:label>has exposure route</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002243 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002243">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002244"/>
<obo:IAO_0000115>A broad relationship between an exposure event or process and the course takes from the source to the target.</obo:IAO_0000115>
<obo:IAO_0000119 rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">http://purl.obolibrary.org/obo/ExO_0000004</obo:IAO_0000119>
<rdfs:label>has exposure transport path</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002244 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002244">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002410"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/RO_0002310"/>
<obo:IAO_0000115>Any relationship between an exposure event or process and any other entity.</obo:IAO_0000115>
<obo:IAO_0000232>Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving exposure events or processes.</obo:IAO_0000232>
<rdfs:label>related via exposure to</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002245 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002245">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002206"/>
<obo:IAO_0000115>g is over-expressed in t iff g is expressed in t, and the expression level of g is increased relative to some background.</obo:IAO_0000115>
<rdfs:label>over-expressed in</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002246 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002246">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002206"/>
<obo:IAO_0000115>g is under-expressed in t iff g is expressed in t, and the expression level of g is decreased relative to some background.</obo:IAO_0000115>
<rdfs:label>under-expressed in</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002248 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002248">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002249"/>
<obo:IAO_0000112>Any portion of roundup 'has active ingredient' some glyphosate</obo:IAO_0000112>
<obo:IAO_0000115>A relationship that holds between a substance and a chemical entity, if the chemical entity is part of the substance, and the chemical entity forms the biologically active component of the substance.</obo:IAO_0000115>
<oboInOwl:hasExactSynonym>has active substance</oboInOwl:hasExactSynonym>
<oboInOwl:hasRelatedSynonym>has active pharmaceutical ingredient</oboInOwl:hasRelatedSynonym>
<rdfs:label>has active ingredient</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002249 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002249">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<obo:IAO_0000115>inverse of has active ingredient</obo:IAO_0000115>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/RO_0002259"/>
<rdfs:label>active ingredient in'</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002252 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002252">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002375"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002253"/>
<obo:IAO_0000115>b connecting-branch-of s iff b is connected to s, and there exists some tree-like structure t such that the mereological sum of b plus s is either the same as t or a branching-part-of t.</obo:IAO_0000115>
<rdfs:label>connecting branch of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002253 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002253">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002375"/>
<obo:IAO_0000115>inverse of connecting branch of</obo:IAO_0000115>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/RO_0002259"/>
<rdfs:label>has connecting branch</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002254 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002254">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002258"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002255"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000004"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/CARO_0000003"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000051"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002202"/>
</owl:propertyChainAxiom>
<obo:IAO_0000112>Mammalian thymus has developmental contribution from some pharyngeal pouch 3; Mammalian thymus has developmental contribution from some pharyngeal pouch 4 [Kardong]</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">x has developmental contribution from y iff x has some part z such that z develops from y</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:label xml:lang="en">has developmental contribution from</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002255 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002255">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002286"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002385"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002203"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000050"/>
</owl:propertyChainAxiom>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115>inverse of has developmental contribution from</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/RO_0002259"/>
<rdfs:label xml:lang="en">developmentally contributes to</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002256 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002256">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002258"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002257"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/CARO_0000003"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/CARO_0000003"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115>t1 induced_by t2 if there is a process of developmental induction (GO:0031128) with t1 and t2 as interacting participants. t2 causes t1 to change its fate from a precursor anatomical structure type T to T', where T' develops_from T</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000117>David Osumi-Sutherland</obo:IAO_0000117>
<obo:IAO_0000117>Melissa Haendel</obo:IAO_0000117>
<obo:IAO_0000118>induced by</obo:IAO_0000118>
<obo:IAO_0000119 rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/20064205"/>
<obo:IAO_0000119> Developmental Biology, Gilbert, 8th edition, figure 6.5(F)</obo:IAO_0000119>
<obo:IAO_0000119>GO:0001759</obo:IAO_0000119>
<obo:IAO_0000232>We place this under 'developmentally preceded by'. This placement should be examined in the context of reciprocal inductions[cjm]</obo:IAO_0000232>
<rdfs:label xml:lang="en">developmentally induced by</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002257 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002257">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002286"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002386"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 xml:lang="en">Inverse of developmentally induced by</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:label xml:lang="en">developmentally induces</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002258 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002258">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002324"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002286"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000002"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000002"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115>Candidate definition: x developmentally related to y if and only if there exists some developmental process (GO:0032502) p such that x and y both participates in p, and x is the output of p and y is the input of p</obo:IAO_0000115>
<obo:IAO_0000116 rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">false</obo:IAO_0000116>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000232>In general you should not use this relation to make assertions - use one of the more specific relations below this one</obo:IAO_0000232>
<rdfs:comment>This relation groups together various other developmental relations. It is fairly generic, encompassing induction, developmental contribution and direct and transitive develops from</rdfs:comment>
<rdfs:label xml:lang="en">developmentally preceded by</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002260 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002260">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<obo:IAO_0000115>c has-biological-role r iff c has-role r and r is a biological role (CHEBI:24432)</obo:IAO_0000115>
<rdfs:label>has biological role</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002261 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002261">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<obo:IAO_0000115>c has-application-role r iff c has-role r and r is an application role (CHEBI:33232)</obo:IAO_0000115>
<rdfs:label>has application role</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002262 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002262">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
<obo:IAO_0000115>c has-chemical-role r iff c has-role r and r is a chemical role (CHEBI:51086)</obo:IAO_0000115>
<rdfs:label>has chemical role</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002263 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002263">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002264"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002327"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002411"/>
</owl:propertyChainAxiom>
<obo:IAO_0000115>c involved in regulation of p if c enables 'p' and p' causally upstream of p</obo:IAO_0000115>
<rdfs:label>acts upstream of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002264 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002264">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002500"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002327"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002418"/>
</owl:propertyChainAxiom>
<obo:IAO_0000115>c acts upstream of or within p if c is enables 'p' and p' causally upstream of or within p</obo:IAO_0000115>
<oboInOwl:hasRelatedSynonym>affects</oboInOwl:hasRelatedSynonym>
<rdfs:label>acts upstream of or within</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002285 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002285">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002258"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115>x developmentally replaces y if and only if there is some developmental process that causes x to move or to cease to exist, and for the site that was occupied by x to become occupied by y, where y either comes into existence in this site or moves to this site from somewhere else</obo:IAO_0000115>
<obo:IAO_0000116>This relation is intended for cases such as when we have a bone element replacing its cartilage element precursor. Currently most AOs represent this using 'develops from'. We need to decide whether 'develops from' will be generic and encompass replacement, or whether we need a new name for a generic relation that encompasses replacement and development-via-cell-lineage</obo:IAO_0000116>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000118>replaces</obo:IAO_0000118>
<rdfs:label xml:lang="en">developmentally replaces</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002286 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002286">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002384"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115>Inverse of developmentally preceded by</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:label xml:lang="en">developmentally succeeded by</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002287 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002287">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002286"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000050"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002210"/>
</owl:propertyChainAxiom>
<obo:IAO_0000112>'hypopharyngeal eminence' SubClassOf 'part of precursor of' some tongue</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:label xml:lang="en">part of developmental precursor of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002291 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002291">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002206"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002293"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115>x is ubiquitously expressed in y if and only if x is expressed in y, and the majority of cells in y express x</obo:IAO_0000115>
<obo:IAO_0000116>Revisit this term after coordinating with SO/SOM. The domain of this relation should be a sequence, as an instance of a DNA molecule is only expressed in the cell of which it is a part.</obo:IAO_0000116>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:label xml:lang="en">ubiquitously expressed in</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002292 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002292">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002330"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115>Inverse of 'expressed in'</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:label xml:lang="en">expresses</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002293 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002293">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002292"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115>inverse of ubiquiotously expressed in</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/RO_0002259"/>
<rdfs:label xml:lang="en">ubiquitously expresses</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002295 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002295">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002324"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/GO_0008150"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/CARO_0000003"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115>p results in the developmental progression of s iff p is a developmental process and s is an anatomical structure and p causes s to undergo a change in state at some point along its natural developmental cycle (this cycle starts with its formation, through the mature structure, and ends with its loss).</obo:IAO_0000115>
<obo:IAO_0000116>This property and its subproperties are being used primarily for the definition of GO developmental processes. The property hierarchy mirrors the core GO hierarchy. In future we may be able to make do with a more minimal set of properties, but due to the way GO is currently structured we require highly specific relations to avoid incorrect entailments. To avoid this, the corresponding genus terms in GO should be declared mutually disjoint.</obo:IAO_0000116>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<oboInOwl:shorthand rdf:datatype="http://www.w3.org/2001/XMLSchema#string">results_in_developmental_progression_of</oboInOwl:shorthand>
<rdfs:label xml:lang="en">results in developmental progression of</rdfs:label>
<rdfs:seeAlso rdf:resource="http://wiki.geneontology.org/index.php/Ontology_extensions"/>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002296 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002296">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002295"/>
<obo:IAO_0000112 xml:lang="en">every flower development (GO:0009908) results in development of some flower (PO:0009046)</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115>p 'results in development of' c if and only if p is a developmental process and p results in the state of c changing from its initial state as a primordium or anlage through its mature state and to its final state.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000119 rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">http://www.geneontology.org/GO.doc.development.shtml</obo:IAO_0000119>
<oboInOwl:shorthand rdf:datatype="http://www.w3.org/2001/XMLSchema#string">results_in_development_of</oboInOwl:shorthand>
<rdfs:label xml:lang="en">results in development of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002297 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002297">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002234"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002295"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002354"/>
<obo:IAO_0000112>an annotation of gene X to anatomical structure formation with results_in_formation_of UBERON:0000007 (pituitary gland) means that at the beginning of the process a pituitary gland does not exist and at the end of the process a pituitary gland exists.</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">every "endocardial cushion formation" (GO:0003272) results_in_formation_of some "endocardial cushion" (UBERON:0002062)</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000119>GOC:mtg_berkeley_2013</obo:IAO_0000119>
<oboInOwl:shorthand rdf:datatype="http://www.w3.org/2001/XMLSchema#string">results_in_formation_of</oboInOwl:shorthand>
<rdfs:label xml:lang="en">results in formation of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002298 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002298">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002295"/>
<obo:IAO_0000112>an annotation of gene X to cell morphogenesis with results_in_morphogenesis_of CL:0000540 (neuron) means that at the end of the process an input neuron has attained its shape.</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">tongue morphogenesis (GO:0043587) results in morphogenesis of tongue (UBERON:0001723)</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115>The relationship that links an entity with the process that results in the formation and shaping of that entity over time from an immature to a mature state.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000119>GOC:mtg_berkeley_2013</obo:IAO_0000119>
<oboInOwl:shorthand rdf:datatype="http://www.w3.org/2001/XMLSchema#string">results_in_morphogenesis_of</oboInOwl:shorthand>
<rdfs:label xml:lang="en">results in morphogenesis of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002299 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002299">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002295"/>
<obo:IAO_0000112> an annotation of gene X to cell maturation with results_in_maturation_of CL:0000057 (fibroblast) means that the fibroblast is mature at the end of the process</obo:IAO_0000112>
<obo:IAO_0000112 xml:lang="en">bone maturation (GO:0070977) results_in_maturation_of bone (UBERON:0001474)</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115>The relationship that links an entity with a process that results in the progression of the entity over time that is independent of changes in it's shape and results in an end point state of that entity.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000119>GOC:mtg_berkeley_2013</obo:IAO_0000119>
<oboInOwl:shorthand rdf:datatype="http://www.w3.org/2001/XMLSchema#string">results_in_maturation_of</oboInOwl:shorthand>
<rdfs:label xml:lang="en">results in maturation of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002300 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002300">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002552"/>
<obo:IAO_0000112>foramen ovale closure SubClassOf results in disappearance of foramen ovale</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000232>May be merged into parent relation</obo:IAO_0000232>
<oboInOwl:shorthand rdf:datatype="http://www.w3.org/2001/XMLSchema#string">results_in_disappearance_of</oboInOwl:shorthand>
<rdfs:label xml:lang="en">results in disappearance of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002301 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002301">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002552"/>
<obo:IAO_0000112>every mullerian duct regression (GO:0001880) results in regression of some mullerian duct (UBERON:0003890)</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000232>May be merged into parent relation</obo:IAO_0000232>
<rdfs:label xml:lang="en">results in developmental regression of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002302 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002302">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002410"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002606"/>
<obo:IAO_0000115>Inverse of 'is substance that treats'</obo:IAO_0000115>
<dc:creator rdf:datatype="http://www.w3.org/2001/XMLSchema#string">cjm</dc:creator>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/RO_0002259"/>
<rdfs:label>is treated by substance</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002303 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002303">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002321"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/CARO_0000006"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/ENVO_01000254"/>
<obo:IAO_0000112>Hydrozoa (NCBITaxon_6074) SubClassOf 'has habitat' some 'Hydrozoa habitat'
where
'Hydrozoa habitat' SubClassOf overlaps some ('marine environment' (ENVO_00000569) and 'freshwater environment' (ENVO_01000306) and 'wetland' (ENVO_00000043)) and 'has part' some (freshwater (ENVO_00002011) or 'sea water' (ENVO_00002149)) -- http://eol.org/pages/1795/overview</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000428"/>
<obo:IAO_0000115>x 'has habitat' y if and only if: x is an organism, y is a habitat, and y can sustain and allow the growth of a population of xs.</obo:IAO_0000115>
<obo:IAO_0000117>Pier Buttigieg</obo:IAO_0000117>
<obo:IAO_0000118>adapted for living in</obo:IAO_0000118>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:comment>A population of xs will possess adaptations (either evolved naturally or via artifical selection) which permit it to exist and grow in y.</rdfs:comment>
<rdfs:label xml:lang="en">has habitat</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002304 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002304">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002411"/>
<dc:creator rdf:datatype="http://www.w3.org/2001/XMLSchema#string">cjm</dc:creator>
<rdfs:comment>holds between x and y if and only if x is causally upstream of y and the progression of x increases the frequency, rate or extent of y</rdfs:comment>
<rdfs:label>causally upstream of, positive effect</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002305 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002305">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002411"/>
<dc:creator rdf:datatype="http://www.w3.org/2001/XMLSchema#string">cjm</dc:creator>
<rdfs:comment>holds between x and y if and only if x is causally upstream of y and the progression of x decreases the frequency, rate or extent of y</rdfs:comment>
<rdfs:label>causally upstream of, negative effect</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002309 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002309">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002244"/>
<obo:IAO_0000115>A relationship between an exposure event or process and any agent, stimulus, activity, or event that causally effects an organism and interacts with an exposure receptor during an exposure event.</obo:IAO_0000115>
<dc:contributor>Austin Meier</dc:contributor>
<dc:contributor>Chris Mungall</dc:contributor>
<dc:contributor>Marie Angelique Laporte</dc:contributor>
<oboInOwl:created_by rdf:datatype="http://www.w3.org/2001/XMLSchema#string">cjm</oboInOwl:created_by>
<oboInOwl:creation_date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2017-06-05T17:35:04Z</oboInOwl:creation_date>
<rdfs:label>has exposure stimulus</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002312 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002312">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002320"/>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:label xml:lang="en">evolutionary variant of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002313 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002313">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002337"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002313"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000051"/>
</owl:propertyChainAxiom>
<obo:IAO_0000115>Holds between p and c when p is a localization process (localization covers maintenance of localization as well as its establishment) and the outcome of this process is to regulate the localization of c.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000118>regulates localization of</obo:IAO_0000118>
<rdfs:label xml:lang="en">transports or maintains localization of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002314 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002314">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002502"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0000052"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000050"/>
</owl:propertyChainAxiom>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002314"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000050"/>
</owl:propertyChainAxiom>
<obo:IAO_0000115>q inheres in part of w if and only if there exists some p such that q inheres in p and p part of w.</obo:IAO_0000115>
<obo:IAO_0000116>Because part_of is transitive, inheres in is a sub-relation of inheres in part of</obo:IAO_0000116>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000119 rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/20064205"/>
<obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
<rdfs:label xml:lang="en">inheres in part of</rdfs:label>
</owl:ObjectProperty>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/RO_0002314"/>
<owl:annotatedProperty rdf:resource="http://www.w3.org/2002/07/owl#propertyChainAxiom"/>
<owl:annotatedTarget rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0000052"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000050"/>
</owl:annotatedTarget>
<obo:RO_0002582 rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</obo:RO_0002582>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/RO_0002315 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002315">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002295"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/CL_0000000"/>
<obo:IAO_0000112>an annotation of gene X to cell differentiation with results_in_maturation_of CL:0000057 (fibroblast) means that at the end of the process the input cell that did not have features of a fibroblast, now has the features of a fibroblast.</obo:IAO_0000112>
<obo:IAO_0000115>The relationship that links a specified entity with the process that results in an unspecified entity acquiring the features and characteristics of the specified entity</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000119>GOC:mtg_berkeley_2013</obo:IAO_0000119>
<oboInOwl:shorthand rdf:datatype="http://www.w3.org/2001/XMLSchema#string">results_in_acquisition_of_features_of</oboInOwl:shorthand>
<rdfs:label xml:lang="en">results in acquisition of features of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002320 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002320">
<obo:IAO_0000115>A relationship that holds via some environmental process</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000232>Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving the process of evolution.</obo:IAO_0000232>
<rdfs:label xml:lang="en">evolutionarily related to</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002321 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002321">
<obo:IAO_0000115>A relationship that is mediated in some way by the environment or environmental feature (ENVO:00002297)</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000232>Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving ecological interactions</obo:IAO_0000232>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label xml:lang="en">ecologically related to</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002322 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002322">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002321"/>
<obo:IAO_0000116>An experimental relation currently used to connect a feature possessed by an organism (e.g. anatomical structure, biological process, phenotype or quality) to a habitat or environment in which that feature is well suited, adapted or provides a reproductive advantage for the organism. For example, fins to an aquatic environment. Usually this will mean that the structure is adapted for this environment, but we avoid saying this directly - primitive forms of the structure may not have evolved specifically for that environment (for example, early wings were not necessarily adapted for an aerial environment). Note also that this is a statement about the general class of structures - not every instance of a limb need confer an advantage for a terrestrial environment, e.g. if the limb is vestigial.</obo:IAO_0000116>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000118>adapted for</obo:IAO_0000118>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label xml:lang="en">confers advantage in</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002323 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002323">
<obo:IAO_0000115>A mereological relationship or a topological relationship</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000232>Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving parthood or connectivity relationships</obo:IAO_0000232>
<obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
<rdfs:label xml:lang="en">mereotopologically related to</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002324 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002324">
<obo:IAO_0000115>A relationship that holds between entities participating in some developmental process (GO:0032502)</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000232>Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving organismal development</obo:IAO_0000232>
<rdfs:label xml:lang="en">developmentally related to</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002325 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002325">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002323"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<obo:IAO_0000112>Clp1p relocalizes from the nucleolus to the spindle and site of cell division; i.e. it is associated transiently with the spindle pole body and the contractile ring (evidence from GFP fusion). Clp1p colocalizes_with spindle pole body (GO:0005816) and contractile ring (GO:0005826)</obo:IAO_0000112>
<obo:IAO_0000115>a colocalizes_with b if and only if a is transiently or peripherally associated with b[GO].</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000119>http://www.geneontology.org/GO.annotation.conventions.shtml#colocalizes_with</obo:IAO_0000119>
<obo:IAO_0000232>In the context of the Gene Ontology, colocalizes_with may be used for annotating to cellular component terms[GO]</obo:IAO_0000232>
<dc:creator>Gene Ontology Consortium</dc:creator>
<rdfs:label xml:lang="en">colocalizes with</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002326 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002326">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002216"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002329"/>
<obo:IAO_0000112>ATP citrate lyase (ACL) in Arabidopsis: it is a heterooctamer, composed of two types of subunits, ACLA and ACLB in a A(4)B(4) stoichiometry. Neither of the subunits expressed alone give ACL activity, but co-expression results in ACL activity. Both subunits contribute_to the ATP citrate lyase activity.</obo:IAO_0000112>
<obo:IAO_0000112>Subunits of nuclear RNA polymerases: none of the individual subunits have RNA polymerase activity, yet all of these subunits contribute_to DNA-dependent RNA polymerase activity.</obo:IAO_0000112>
<obo:IAO_0000112>eIF2: has three subunits (alpha, beta, gamma); one binds GTP; one binds RNA; the whole complex binds the ribosome (all three subunits are required for ribosome binding). So one subunit is annotated to GTP binding and one to RNA binding without qualifiers, and all three stand in the contributes_to relationship to "ribosome binding". And all three are part_of an eIF2 complex</obo:IAO_0000112>
<obo:IAO_0000116>We would like to say
if and only if
exists c', p'
c part_of c' and c' capable_of p
and
c capable_of p' and p' part_of p
then
c contributes_to p
However, this is not possible in OWL. We instead make this relation a sub-relation of the two chains, which gives us the inference in the one direction.</obo:IAO_0000116>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000119>http://www.geneontology.org/GO.annotation.conventions.shtml#contributes_to</obo:IAO_0000119>
<obo:IAO_0000232>In the context of the Gene Ontology, contributes_to may be used only with classes from the molecular function ontology. </obo:IAO_0000232>
<rdfs:label xml:lang="en">contributes to</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002327 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002327">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002215"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002333"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002327"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000051"/>
</owl:propertyChainAxiom>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002327"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002017"/>
</owl:propertyChainAxiom>
<obo:IAO_0000112>a particular instances of akt-2 enables some instance of protein kinase activity</obo:IAO_0000112>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000118>catalyzes</obo:IAO_0000118>
<obo:IAO_0000118>executes</obo:IAO_0000118>
<obo:IAO_0000118>has</obo:IAO_0000118>
<obo:IAO_0000118>is catalyzing</obo:IAO_0000118>
<obo:IAO_0000118>is executing</obo:IAO_0000118>
<obo:IAO_0000232>This relation differs from the parent relation 'capable of' in that the parent is weaker and only expresses a capability that may not be actually realized, whereas this relation is always realized.</obo:IAO_0000232>
<obo:IAO_0000232>This relation is currently used experimentally by the Gene Ontology Consortium. It may not be stable and may be obsoleted at some future time.</obo:IAO_0000232>
<rdfs:label xml:lang="en">enables</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002328 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002328">
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000232>This is a grouping relation that collects relations used for the purpose of connecting structure and function</obo:IAO_0000232>
<rdfs:label xml:lang="en">functionally related to</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002329 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002329">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002328"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000050"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002215"/>
</owl:propertyChainAxiom>
<obo:IAO_0000115>this relation holds between c and p when c is part of some c', and c' is capable of p.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000118 rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">false</obo:IAO_0000118>
<rdfs:label xml:lang="en">part of structure that is capable of</rdfs:label>
</owl:ObjectProperty>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/RO_0002329"/>
<owl:annotatedProperty rdf:resource="http://www.w3.org/2002/07/owl#propertyChainAxiom"/>
<owl:annotatedTarget rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000050"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002215"/>
</owl:annotatedTarget>
<obo:RO_0002581 rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</obo:RO_0002581>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/RO_0002330 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002330">
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000002"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000002"/>
<obo:IAO_0000115>holds between two entities when some genome-level process such as gene expression is involved. This includes transcriptional, spliceosomal events. These relations can be used between either macromolecule entities (such as regions of nucleic acid) or between their abstract informational counterparts.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000232>Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving the genome of an organism</obo:IAO_0000232>
<rdfs:label xml:lang="en">genomically related to</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002331 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002331">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002431"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002327"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000050"/>
</owl:propertyChainAxiom>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002331"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000050"/>
</owl:propertyChainAxiom>
<obo:IAO_0000115>c involved_in p if and only if c enables some process p', and p' is part of p</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000118>actively involved in</obo:IAO_0000118>
<obo:IAO_0000118>enables part of</obo:IAO_0000118>
<rdfs:label xml:lang="en">involved in</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002332 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002332">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002328"/>
<obo:IAO_0000112>every cellular sphingolipid homeostasis process regulates_level_of some sphingolipid</obo:IAO_0000112>
<obo:IAO_0000115>p regulates levels of c if p regulates some amount (PATO:0000070) of c</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000119 rdf:resource="http://purl.obolibrary.org/obo/ro/docs/causal-relations"/>
<obo:IAO_0000589>regulates levels of (process to entity)</obo:IAO_0000589>
<rdfs:label xml:lang="en">regulates levels of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002333 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002333">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002328"/>
<rdfs:subPropertyOf>
<rdf:Description>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002215"/>
</rdf:Description>
</rdfs:subPropertyOf>
<obo:IAO_0000115>inverse of enables</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:label xml:lang="en">enabled by</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002334 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002334">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002427"/>
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
<obo:IAO_0000115>inverse of regulates</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000589>regulated by (processual)</obo:IAO_0000589>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/RO_0002259"/>
<rdfs:label xml:lang="en">regulated by</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002335 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002335">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002334"/>
<obo:IAO_0000115>inverse of negatively regulates</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/RO_0002259"/>
<rdfs:label xml:lang="en">negatively regulated by</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002336 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002336">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002334"/>
<obo:IAO_0000115>inverse of positively regulates</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/RO_0002259"/>
<rdfs:label xml:lang="en">positively regulated by</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002337 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002337">
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000002"/>
<obo:IAO_0000115>A relationship that holds via some process of localization</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:label xml:lang="en">related via localization to</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002338 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002338">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002344"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002338"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000050"/>
</owl:propertyChainAxiom>
<obo:IAO_0000115>This relationship holds between p and l when p is a transport or localization process in which the outcome is to move some cargo c from some initial location l to some destination.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:label xml:lang="en">has target start location</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002339 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002339">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002344"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002339"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000050"/>
</owl:propertyChainAxiom>
<obo:IAO_0000115>This relationship holds between p and l when p is a transport or localization process in which the outcome is to move some cargo c from a an initial location to some destination l.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:label xml:lang="en">has target end location</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002340 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002340">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002020"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002340"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000051"/>
</owl:propertyChainAxiom>
<obo:IAO_0000115>Holds between p and c when p is a transportation or localization process and the outcome of this process is to move c to a destination that is part of some s, where the start location of c is part of the region that surrounds s.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:label xml:lang="en">imports</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002341 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002341">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002337"/>
<obo:IAO_0000115>Holds between p and l when p is a transportation or localization process and the outcome of this process is to move c from one location to another, and the route taken by c follows a path that is aligned_with l </obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:label xml:lang="en">results in transport along</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002342 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002342">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002021"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002344"/>
<obo:IAO_0000115>Holds between p and m when p is a transportation or localization process and the outcome of this process is to move c from one location to another, and the route taken by c follows a path that crosses m.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:label xml:lang="en">results in transport across</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002343 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002343">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002295"/>
<obo:IAO_0000112>'pollen tube growth' results_in growth_of some 'pollen tube'</obo:IAO_0000112>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:label xml:lang="en">results in growth of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002344 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002344">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002337"/>
<obo:IAO_0000112>'mitochondrial transport' results_in_transport_to_from_or_in some mitochondrion (GO:0005739)</obo:IAO_0000112>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:label xml:lang="en">results in transport to from or in</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002345 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002345">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002020"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002345"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000051"/>
</owl:propertyChainAxiom>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:label xml:lang="en">exports</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002348 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002348">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002295"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/CL_0000000"/>
<obo:IAO_0000112>an annotation of gene X to cell commitment with results_in_commitment_to CL:0000540 (neuron) means that at the end of the process an unspecified cell has been specified and determined to develop into a neuron.</obo:IAO_0000112>
<obo:IAO_0000115>p 'results in commitment to' c if and only if p is a developmental process and c is a cell and p results in the state of c changing such that is can only develop into a single cell type.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000119 rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">http://www.geneontology.org/GO.doc.development.shtml#fate</obo:IAO_0000119>
<rdfs:label xml:lang="en">results in commitment to</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002349 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002349">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002295"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/CL_0000000"/>
<obo:IAO_0000115>p 'results in determination of' c if and only if p is a developmental process and c is a cell and p results in the state of c changing to be determined. Once a cell becomes determined, it becomes committed to differentiate down a particular pathway regardless of its environment.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000119 rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">http://www.geneontology.org/GO.doc.development.shtml#fate</obo:IAO_0000119>
<rdfs:label xml:lang="en">results in determination of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002352 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002352">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002328"/>
<obo:IAO_0000115>inverse of has input</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/RO_0002259"/>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label xml:lang="en">input of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002353 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002353">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002328"/>
<obo:IAO_0000115>inverse of has output</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/RO_0002259"/>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label xml:lang="en">output of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002354 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002354">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002353"/>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:label xml:lang="en">formed as result of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002355 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002355">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002295"/>
<obo:IAO_0000115>A relationship between a process and an anatomical entity such that the process contributes to the act of creating the structural organization of the anatomical entity.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:label xml:lang="en">results in structural organization of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002356 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002356">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002295"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/CL_0000000"/>
<obo:IAO_0000115>The relationship linking a cell and its participation in a process that results in the fate of the cell being specified. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. </obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000119 rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">http://www.geneontology.org/GO.doc.development.shtml#fate</obo:IAO_0000119>
<rdfs:label xml:lang="en">results in specification of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002357 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002357">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002295"/>
<obo:IAO_0000115>p results in developmental induction of c if and only if p is a collection of cell-cell signaling processes that signal to a neighbouring tissue that is the precursor of the mature c, where the signaling results in the commitment to cell types necessary for the formation of c.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:label xml:lang="en">results in developmental induction of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002360 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002360">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002131"/>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<dc:source rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">http://neurolex.org/wiki/Property:DendriteLocation</dc:source>
<rdfs:label xml:lang="en">has dendrite location</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002371 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002371">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002170"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002177"/>
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#SymmetricProperty"/>
<obo:IAO_0000115>a is attached to b if and only if a and b are discrete objects or object parts, and there are physical connections between a and b such that a force pulling a will move b, or a force pulling b will move a</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label xml:lang="en">attached to</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002372 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002372">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002371"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002567"/>
<obo:IAO_0000115 xml:lang="en">m has_muscle_origin s iff m is attached_to s, and it is the case that when m contracts, s does not move. The site of the origin tends to be more proximal and have greater mass than what the other end attaches to.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">Wikipedia:Insertion_(anatomy)</obo:IAO_0000119>
<rdfs:label xml:lang="en">has muscle origin</rdfs:label>
<rdfs:seeAlso rdf:resource="http://dbpedia.org/property/origin"/>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002373 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002373">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002371"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002567"/>
<obo:IAO_0000115 xml:lang="en">m has_muscle_insertion s iff m is attaches_to s, and it is the case that when m contracts, s moves. Insertions are usually connections of muscle via tendon to bone.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">Wikipedia:Insertion_(anatomy)</obo:IAO_0000119>
<rdfs:label xml:lang="en">has muscle insertion</rdfs:label>
<rdfs:seeAlso rdf:resource="http://dbpedia.org/property/insertion"/>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002374 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002374">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002320"/>
<obo:IAO_0000112 rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">false</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000428"/>
<obo:IAO_0000115 xml:lang="en">x has_fused_element y iff: there exists some z : x has_part z, z homologous_to y, and y is a distinct element, the boundary between x and z is largely fiat</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000119 rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/22293552"/>
<rdfs:comment xml:lang="en">A has_fused_element B does not imply that A has_part some B: rather than A has_part some B', where B' that has some evolutionary relationship to B.</rdfs:comment>
<rdfs:label xml:lang="en">has fused element</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002375 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002375">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002323"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000428"/>
<obo:IAO_0000115>A relationship that holds between two material entities in a system of connected structures, where the branching relationship holds based on properties of the connecting network.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000232>Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving branching relationships</obo:IAO_0000232>
<obo:IAO_0000232>This relation can be used for geographic features (e.g. rivers) as well as anatomical structures (plant branches and roots, leaf veins, animal veins, arteries, nerves)</obo:IAO_0000232>
<rdfs:label xml:lang="en">in branching relationship with</rdfs:label>
<rdfs:seeAlso rdf:resource="http://purl.obolibrary.org/obo/ro/docs/branching_part_of.png"/>
<foaf:page rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://github.com/obophenotype/uberon/issues/170</foaf:page>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002376 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002376">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002375"/>
<obo:IAO_0000112>Deschutes River tributary_of Columbia River</obo:IAO_0000112>
<obo:IAO_0000112>inferior epigastric vein tributary_of external iliac vein</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000428"/>
<obo:IAO_0000115>x tributary_of y if and only if x a channel for the flow of a substance into y, where y is larger than x. If x and y are hydrographic features, then y is the main stem of a river, or a lake or bay, but not the sea or ocean. If x and y are anatomical, then y is a vein.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000118>drains into</obo:IAO_0000118>
<obo:IAO_0000118>drains to</obo:IAO_0000118>
<obo:IAO_0000118>tributary channel of</obo:IAO_0000118>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Tributary</obo:IAO_0000119>
<obo:IAO_0000119>http://www.medindia.net/glossary/venous_tributary.htm</obo:IAO_0000119>
<obo:IAO_0000232 rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">This relation can be used for geographic features (e.g. rivers) as well as anatomical structures (veins, arteries)</obo:IAO_0000232>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label xml:lang="en">tributary of</rdfs:label>
<rdfs:seeAlso rdf:resource="http://dbpedia.org/ontology/drainsTo"/>
<rdfs:seeAlso rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">http://en.wikipedia.org/wiki/Tributary</rdfs:seeAlso>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002377 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002377">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002375"/>
<obo:IAO_0000112>Deschutes River distributary_of Little Lava Lake</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000428"/>
<obo:IAO_0000115>x distributary_of y if and only if x is capable of channeling the flow of a substance to y, where y channels less of the substance than x</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000118>branch of</obo:IAO_0000118>
<obo:IAO_0000118>distributary channel of</obo:IAO_0000118>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Distributary</obo:IAO_0000119>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:comment>This is both a mereotopological relationship and a relationship defined in connection to processes. It concerns both the connecting structure, and how this structure is disposed to causally affect flow processes</rdfs:comment>
<rdfs:label xml:lang="en">distributary of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002378 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002378">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002377"/>
<rdfs:subPropertyOf>
<rdf:Description>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002376"/>
</rdf:Description>
</rdfs:subPropertyOf>
<owl:propertyDisjointWith rdf:resource="http://purl.obolibrary.org/obo/RO_0002382"/>
<owl:propertyDisjointWith rdf:resource="http://purl.obolibrary.org/obo/RO_0002383"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000428"/>
<obo:IAO_0000115>x anabranch_of y if x is a distributary of y (i.e. it channels a from a larger flow from y) and x ultimately channels the flow back into y.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000118>anastomoses with</obo:IAO_0000118>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label xml:lang="en">anabranch of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002379 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002379">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002131"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0001025"/>
<rdf:Description>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0001025"/>
</rdf:Description>
</owl:propertyChainAxiom>
<obo:IAO_0000112>A lump of clay and a statue</obo:IAO_0000112>
<obo:IAO_0000115>x spatially_coextensive_with y if and inly if x and y have the same location</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000232>This relation is added for formal completeness. It is unlikely to be used in many practical scenarios</obo:IAO_0000232>
<rdfs:label xml:lang="en">spatially coextensive with</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002380 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002380">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002375"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002569"/>
<rdfs:range>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000053"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0000402"/>
</owl:Restriction>
</rdfs:range>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002377"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002381"/>
</owl:propertyChainAxiom>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000428"/>
<obo:IAO_0000115>x is a branching part of y if and only if x is part of y and x is connected directly or indirectly to the main stem of y</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label xml:lang="en">branching part of</rdfs:label>
<rdfs:seeAlso>FMA:85994</rdfs:seeAlso>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002381 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002381">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002375"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000428"/>
<obo:IAO_0000115>x main_stem_of y if y is a branching structure and x is a channel that traces a linear path through y, such that x has higher capacity than any other such path.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label xml:lang="en">main stem of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002382 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002382">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002377"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000428"/>
<obo:IAO_0000115>x proper_distributary_of y iff x distributary_of y and x does not flow back into y</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label xml:lang="en">proper distributary of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002383 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002383">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002376"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000428"/>
<obo:IAO_0000115>x proper_tributary_of y iff x tributary_of y and x does not originate from y</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label xml:lang="en">proper tributary of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002384 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002384">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002324"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000428"/>
<obo:IAO_0000115 xml:lang="en">x has developmental potential involving y iff x is capable of a developmental process with output y. y may be the successor of x, or may be a different structure in the vicinity (as for example in the case of developmental induction).</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:label xml:lang="en">has developmental potential involving</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002385 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002385">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002384"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000428"/>
<obo:IAO_0000115 xml:lang="en">x has potential to developmentrally contribute to y iff x developmentally contributes to y or x is capable of developmentally contributing to y</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:label xml:lang="en">has potential to developmentally contribute to</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002386 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002386">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002384"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000428"/>
<obo:IAO_0000115 xml:lang="en">x has potential to developmentally induce y iff x developmentally induces y or x is capable of developmentally inducing y</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:label xml:lang="en">has potential to developmentally induce</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002387 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002387">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002384"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000428"/>
<obo:IAO_0000115 xml:lang="en">x has the potential to develop into y iff x develops into y or if x is capable of developing into y</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:label xml:lang="en">has potential to develop into</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002388 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002388">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002387"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000428"/>
<obo:IAO_0000115 xml:lang="en">x has potential to directly develop into y iff x directly develops into y or x is capable of directly developing into y</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:label xml:lang="en">has potential to directly develop into</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002400 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002400">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002233"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002224"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002400"/>
</owl:propertyChainAxiom>
<obo:IAO_0000112>'protein catabolic process' SubClassOf has_direct_input some protein</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000428"/>
<obo:IAO_0000115>p has direct input c iff c is a participant in p, c is present at the start of p, and the state of c is modified during p.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000118>directly consumes</obo:IAO_0000118>
<obo:IAO_0000232>This is likely to be obsoleted. A candidate replacement would be a new relation 'has bound input' or 'has substrate'</obo:IAO_0000232>
<rdfs:label xml:lang="en">has direct input</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002401 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002401">
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000428"/>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:comment>Likely to be obsoleted. See:
https://docs.google.com/document/d/1QMhs9J-P_q3o_rDh-IX4ZEnz0PnXrzLRVkI3vvz8NEQ/edit</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">obsolete has indirect input</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002402 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002402">
<obo:IAO_0000112>translation SubClassOf has_direct_output some protein</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000428"/>
<obo:IAO_0000115>p has direct input c iff c is a participanti n p, c is present at the end of p, and c is not present at the beginning of c. </obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000118>directly produces</obo:IAO_0000118>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">obsolete has direct output</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002403 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002403">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002234"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002411"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002402"/>
</owl:propertyChainAxiom>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000428"/>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:comment>Likely to be obsoleted. See:
https://docs.google.com/document/d/1QMhs9J-P_q3o_rDh-IX4ZEnz0PnXrzLRVkI3vvz8NEQ/edit</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">obsolete has indirect output</rdfs:label>
<owl:deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:deprecated>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002404 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002404">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000062"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002427"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002411"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000428"/>
<obo:IAO_0000115>inverse of upstream of</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:label xml:lang="en">causally downstream of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002405 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002405">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002087"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002404"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002412"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000428"/>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:label xml:lang="en">immediately causally downstream of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002406 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002406">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002629"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000428"/>
<obo:IAO_0000115>p directly activates q if and only if p is immediately upstream of q and p is the realization of a function to increase the rate or activity of q</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000118>directly positively regulates</obo:IAO_0000118>
<obo:IAO_0000119 rdf:resource="http://purl.obolibrary.org/obo/ro/docs/causal-relations"/>
<obo:IAO_0000589>directly activates (process to process)</obo:IAO_0000589>
<rdfs:label xml:lang="en">directly activates</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002407 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002407">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002213"/>
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002406"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002406"/>
</owl:propertyChainAxiom>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002406"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002407"/>
</owl:propertyChainAxiom>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002407"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002406"/>
</owl:propertyChainAxiom>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002409"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002409"/>
</owl:propertyChainAxiom>
<obo:IAO_0000115>p directly activates q if and only if p is immediately upstream of q and p is the realization of a function to increase the rate or activity of q</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000118>indirectly positively regulates</obo:IAO_0000118>
<obo:RO_0002579 rdf:resource="http://purl.obolibrary.org/obo/RO_0002213"/>
<rdfs:label xml:lang="en">indirectly activates</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002408 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002408">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002630"/>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000118>directly negatively regulates</obo:IAO_0000118>
<obo:IAO_0000119 rdf:resource="http://purl.obolibrary.org/obo/ro/docs/causal-relations"/>
<obo:IAO_0000589>directly inhibits (process to process)</obo:IAO_0000589>
<rdfs:label xml:lang="en">directly inhibits</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002409 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002409">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002212"/>
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002408"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002408"/>
</owl:propertyChainAxiom>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002408"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002409"/>
</owl:propertyChainAxiom>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002409"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002408"/>
</owl:propertyChainAxiom>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000428"/>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000118>indirectly negatively regulates</obo:IAO_0000118>
<obo:RO_0002579 rdf:resource="http://purl.obolibrary.org/obo/RO_0002212"/>
<rdfs:label xml:lang="en">indirectly inhibits</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002410 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002410">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002609"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000428"/>
<obo:IAO_0000115>This relation groups causal relations between material entities and causal relations between processes</obo:IAO_0000115>
<obo:IAO_0000116>This branch of the ontology deals with causal relations between entities. It is divided into two branches: causal relations between occurrents/processes, and causal relations between material entities. We take an 'activity flow-centric approach', with the former as primary, and define causal relations between material entities in terms of causal relations between occurrents.
To define causal relations in an activity-flow type network, we make use of 3 primitives:
* Temporal: how do the intervals of the two occurrents relate?
* Is the causal relation regulatory?
* Is the influence positive or negative
The first of these can be formalized in terms of the Allen Interval Algebra. Informally, the 3 bins we care about are 'direct', 'indirect' or overlapping. Note that all causal relations should be classified under a RO temporal relation (see the branch under 'temporally related to'). Note that all causal relations are temporal, but not all temporal relations are causal. Two occurrents can be related in time without being causally connected. We take causal influence to be primitive, elucidated as being such that has the upstream changed, some qualities of the donwstream would necessarily be modified.
For the second, we consider a relationship to be regulatory if the system in which the activities occur is capable of altering the relationship to achieve some objective. This could include changing the rate of production of a molecule.
For the third, we consider the effect of the upstream process on the output(s) of the downstream process. If the level of output is increased, or the rate of production of the output is increased, then the direction is increased. Direction can be positive, negative or neutral or capable of either direction. Two positives in succession yield a positive, two negatives in succession yield a positive, otherwise the default assumption is that the net effect is canceled and the influence is neutral.
Each of these 3 primitives can be composed to yield a cross-product of different relation types.</obo:IAO_0000116>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000232>Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect.</obo:IAO_0000232>
<rdfs:label xml:lang="en">causally related to</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002411 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002411">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000063"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002418"/>
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000428"/>
<obo:IAO_0000115>p is causally upstream of q if and only if p precedes q and p and q are linked in a causal chain</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:label xml:lang="en">causally upstream of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002412 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002412">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002090"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002411"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000428"/>
<obo:IAO_0000115>p is immediately causally upstream of q iff both (a) p immediately precedes q and (b) p is causally upstream of q. In addition, the output of p must be an input of q.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:RO_0002575 rdf:resource="http://purl.obolibrary.org/obo/RO_0002411"/>
<rdfs:label xml:lang="en">immediately causally upstream of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002413 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002413">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002412"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002414"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002402"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002400"/>
</owl:propertyChainAxiom>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000428"/>
<obo:IAO_0000115>p1 directly provides input for p2 iff there exists some c such that p1 has_output c and p2 has_input c</obo:IAO_0000115>
<obo:IAO_0000116>This is currently called 'directly provides input for' to be consistent with our terminology where we use 'direct' whenever two occurrents succeed one another directly. We may relabel this simply 'provides input for', as directness is implicit</obo:IAO_0000116>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000119 rdf:resource="http://purl.obolibrary.org/obo/ro/docs/causal-relations"/>
<obo:IAO_0000589>directly provides input for (process to process)</obo:IAO_0000589>
<rdfs:label xml:lang="en">directly provides input for</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002414 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002414">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002411"/>
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000428"/>
<obo:IAO_0000115>transitive form of directly_provides_input_for</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000232>This is a grouping relation that should probably not be used in annotation. Consider instead the child relation 'directly provides input for' (which may later be relabeled simply to 'provides input for')</obo:IAO_0000232>
<obo:IAO_0000589>transitively provides input for (process to process)</obo:IAO_0000589>
<rdfs:label xml:lang="en">transitively provides input for</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002418 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002418">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002501"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002427"/>
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
<obo:IAO_0000115>p 'causally upstream or within' q iff (1) the end of p is before the end of q and (2) the execution of p exerts some causal influence over the outputs of q; i.e. if p was abolished or the outputs of p were to be modified, this would necessarily affect q.</obo:IAO_0000115>
<obo:IAO_0000116>We would like to make this disjoint with 'preceded by', but this is prohibited in OWL2</obo:IAO_0000116>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000118>influences (processual)</obo:IAO_0000118>
<oboInOwl:hasRelatedSynonym>affects</oboInOwl:hasRelatedSynonym>
<rdfs:label>causally upstream of or within</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002424 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002424">
<obo:IAO_0000116 rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">false</obo:IAO_0000116>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:comment>This is an exploratory relation</rdfs:comment>
<rdfs:label xml:lang="en">differs in</rdfs:label>
<rdfs:seeAlso rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://code.google.com/p/phenotype-ontologies/w/edit/PhenotypeModelCompetencyQuestions</rdfs:seeAlso>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002425 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002425">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002424"/>
<rdfs:range>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000004"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000015"/>
</owl:unionOf>
</owl:Class>
</rdfs:range>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:label xml:lang="en">differs in attribute of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002426 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002426">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002424"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000020"/>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:label xml:lang="en">differs in attribute</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002427 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002427">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002501"/>
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
<obo:IAO_0000115>inverse of causally upstream of or within</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000119 rdf:resource="http://purl.obolibrary.org/obo/ro/docs/causal-relations"/>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/RO_0002259"/>
<rdfs:label>causally downstream of or within</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002428 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002428">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002263"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002431"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002327"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002211"/>
</owl:propertyChainAxiom>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002331"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002211"/>
</owl:propertyChainAxiom>
<obo:IAO_0000115>c involved in regulation of p if c is involved in some 'p' and p' regulates some p</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:label>involved in regulation of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002429 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002429">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002428"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002327"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002213"/>
</owl:propertyChainAxiom>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002331"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002213"/>
</owl:propertyChainAxiom>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:label>involved in positive regulation of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002430 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002430">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002428"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002327"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002212"/>
</owl:propertyChainAxiom>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002331"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002212"/>
</owl:propertyChainAxiom>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:label>involved in negative regulation of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002431 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002431">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002264"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002328"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002500"/>
<obo:IAO_0000115>c involved in or regulates p if and only if either (i) c is involved in p or (ii) c is involved in regulation of p</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000118>involved in or reguates</obo:IAO_0000118>
<rdfs:label>involved in or involved in regulation of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002432 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002432">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002131"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002328"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002327"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000066"/>
</owl:propertyChainAxiom>
<obo:IAO_0000112>A protein that enables activity in a cytosol.</obo:IAO_0000112>
<obo:IAO_0000115>c executes activity in d if and only if c enables p and p occurs_in d. Assuming no action at a distance by gene products, if a gene product enables (is capable of) a process that occurs in some structure, it must have at least some part in that structure.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000118>executes activity in</obo:IAO_0000118>
<oboInOwl:hasExactSynonym>enables activity in</oboInOwl:hasExactSynonym>
<rdfs:comment></rdfs:comment>
<rdfs:label>is active in</rdfs:label>
</owl:ObjectProperty>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/RO_0002432"/>
<owl:annotatedProperty rdf:resource="http://www.w3.org/2002/07/owl#propertyChainAxiom"/>
<owl:annotatedTarget rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002327"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000066"/>
</owl:annotatedTarget>
<obo:RO_0002581 rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</obo:RO_0002581>
</owl:Axiom>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/RO_0002432"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000115"/>
<owl:annotatedTarget>c executes activity in d if and only if c enables p and p occurs_in d. Assuming no action at a distance by gene products, if a gene product enables (is capable of) a process that occurs in some structure, it must have at least some part in that structure.</owl:annotatedTarget>
<oboInOwl:hasDbXref>GOC:cjm</oboInOwl:hasDbXref>
<oboInOwl:hasDbXref>GOC:dos</oboInOwl:hasDbXref>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/RO_0002433 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002433">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002131"/>
<obo:IAO_0000115>p contributes to morphology of w if and only if a change in the morphology of p entails a change in the morphology of w. Examples: every skull contributes to morphology of the head which it is a part of. Counter-example: nuclei do not generally contribute to the morphology of the cell they are part of, as they are buffered by cytoplasm.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:label>contributes to morphology of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002434 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002434">
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#SymmetricProperty"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<obo:IAO_0000115>A relationship that holds between two entities in which the processes executed by the two entities are causally connected.</obo:IAO_0000115>
<obo:IAO_0000116 rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">Considering relabeling as 'pairwise interacts with'</obo:IAO_0000116>
<obo:IAO_0000116>This relation and all sub-relations can be applied to either (1) pairs of entities that are interacting at any moment of time (2) populations or species of entity whose members have the disposition to interact (3) classes whose members have the disposition to interact.</obo:IAO_0000116>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000232>Note that this relationship type, and sub-relationship types may be redundant with process terms from other ontologies. For example, the symbiotic relationship hierarchy parallels GO. The relations are provided as a convenient shortcut. Consider using the more expressive processual form to capture your data. In the future, these relations will be linked to their cognate processes through rules.</obo:IAO_0000232>
<oboInOwl:hasExactSynonym>in pairwise interaction with</oboInOwl:hasExactSynonym>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label>interacts with</rdfs:label>
<rdfs:seeAlso rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">http://purl.obolibrary.org/obo/MI_0914</rdfs:seeAlso>
<foaf:page rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://github.com/oborel/obo-relations/wiki/InteractionRelations</foaf:page>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002435 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002435">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002434"/>
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#SymmetricProperty"/>
<obo:IAO_0000116>An interaction that holds between two genetic entities (genes, alleles) through some genetic interaction (e.g. epistasis)</obo:IAO_0000116>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:label>genetically interacts with</rdfs:label>
<rdfs:seeAlso rdf:resource="http://purl.obolibrary.org/obo/ECO_0000316"/>
<rdfs:seeAlso rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">http://purl.obolibrary.org/obo/MI_0208</rdfs:seeAlso>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002436 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002436">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002434"/>
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#SymmetricProperty"/>
<obo:IAO_0000115>An interaction relationship in which the two partners are molecular entities that directly physically interact with each other for example via a stable binding interaction or a brief interaction during which one modifies the other.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000118>binds</obo:IAO_0000118>
<obo:IAO_0000118>molecularly binds with</obo:IAO_0000118>
<rdfs:label>molecularly interacts with</rdfs:label>
<rdfs:seeAlso rdf:resource="http://purl.obolibrary.org/obo/ECO_0000353"/>
<rdfs:seeAlso rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">http://purl.obolibrary.org/obo/MI_0915</rdfs:seeAlso>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002437 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002437">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002321"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002434"/>
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#SymmetricProperty"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<obo:IAO_0000115>An interaction relationship in which at least one of the partners is an organism and the other is either an organism or an abiotic entity with which the organism interacts.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000118>interacts with on organism level</obo:IAO_0000118>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label>biotically interacts with</rdfs:label>
<rdfs:seeAlso rdf:resource="http://dx.doi.org/10.1016/j.ecoinf.2014.08.005"/>
<rdfs:seeAlso>http://eol.org/schema/terms/interactsWith</rdfs:seeAlso>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002438 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002438">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002574"/>
<obo:IAO_0000115>An interaction relationship in which the partners are related via a feeding relationship.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label>trophically interacts with</rdfs:label>
<rdfs:seeAlso rdf:resource="http://dx.doi.org/10.1016/j.ecoinf.2014.08.005"/>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002439 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002439">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002438"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002458"/>
<obo:IAO_0000112>A wasp killing a Monarch larva in order to feed to offspring [http://www.inaturalist.org/observations/2942824]</obo:IAO_0000112>
<obo:IAO_0000112>Baleen whale preys on krill</obo:IAO_0000112>
<obo:IAO_0000115>An interaction relationship involving a predation process, where the subject kills the target in order to eat it or to feed to siblings, offspring or group members</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000117>Jorrit Poelen</obo:IAO_0000117>
<obo:IAO_0000117>Katja Shulz</obo:IAO_0000117>
<obo:IAO_0000118>is subject of predation interaction with</obo:IAO_0000118>
<obo:IAO_0000118>preys upon</obo:IAO_0000118>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label>preys on</rdfs:label>
<rdfs:seeAlso>http://eol.org/schema/terms/preysUpon</rdfs:seeAlso>
<rdfs:seeAlso>http://www.inaturalist.org/observations/2942824</rdfs:seeAlso>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002440 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002440">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002574"/>
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#SymmetricProperty"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002461"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002465"/>
<rdf:Description>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002461"/>
</rdf:Description>
</owl:propertyChainAxiom>
<obo:IAO_0000115>A biotic interaction in which the two organisms live together in more or less intimate association.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000119 rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">http://www.ncbi.nlm.nih.gov/pubmed/19278549</obo:IAO_0000119>
<obo:IAO_0000232>We follow GO and PAMGO in using 'symbiosis' as the broad term encompassing mutualism through parasitism</obo:IAO_0000232>
<obo:RO_0002561 rdf:resource="http://purl.obolibrary.org/obo/GO_0044403"/>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label>symbiotically interacts with</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002441 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002441">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002440"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002461"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002466"/>
<rdf:Description>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002461"/>
</rdf:Description>
</owl:propertyChainAxiom>
<obo:IAO_0000115>An interaction relationship between two organisms living together in more or less intimate association in a relationship in which one benefits and the other is unaffected (GO).</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000119 rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">http://www.ncbi.nlm.nih.gov/pubmed/19278549</obo:IAO_0000119>
<obo:RO_0002561 rdf:resource="http://purl.obolibrary.org/obo/GO_0085031"/>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label>commensually interacts with</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002442 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002442">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002440"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002461"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002467"/>
<rdf:Description>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002461"/>
</rdf:Description>
</owl:propertyChainAxiom>
<obo:IAO_0000115>An interaction relationship between two organisms living together in more or less intimate association in a relationship in which both organisms benefit from each other (GO).</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000119 rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">http://www.ncbi.nlm.nih.gov/pubmed/19278549</obo:IAO_0000119>
<obo:RO_0002561 rdf:resource="http://purl.obolibrary.org/obo/GO_0085030"/>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label>mutualistically interacts with</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002443 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002443">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002440"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002461"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002468"/>
<rdf:Description>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002461"/>
</rdf:Description>
</owl:propertyChainAxiom>
<obo:IAO_0000115>An interaction relationship between two organisms living together in more or less intimate association in a relationship in which association is disadvantageous or destructive to one of the organisms (GO).</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000119 rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">http://www.ncbi.nlm.nih.gov/pubmed/19278549</obo:IAO_0000119>
<obo:IAO_0000232>This relation groups a pair of inverse relations, parasite of and parasitized by</obo:IAO_0000232>
<obo:RO_0002561 rdf:resource="http://purl.obolibrary.org/obo/GO_0072519"/>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label>interacts with via parasite-host interaction</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002444 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002444">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002443"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002454"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002445"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002462"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002468"/>
<rdf:Description>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002463"/>
</rdf:Description>
</owl:propertyChainAxiom>
<obo:IAO_0000112>Pediculus humanus capitis parasite of human</obo:IAO_0000112>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000118>parasitizes</obo:IAO_0000118>
<obo:RO_0002560 rdf:resource="http://purl.obolibrary.org/obo/GO_0072519"/>
<oboInOwl:hasExactSynonym>direct parasite of</oboInOwl:hasExactSynonym>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label>parasite of</rdfs:label>
<rdfs:seeAlso>http://eol.org/schema/terms/parasitizes</rdfs:seeAlso>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002445 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002445">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002443"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002453"/>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000118>has parasite</obo:IAO_0000118>
<obo:IAO_0000118>parasitised by</obo:IAO_0000118>
<oboInOwl:hasExactSynonym>directly parasitized by</oboInOwl:hasExactSynonym>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label>parasitized by</rdfs:label>
<rdfs:seeAlso>http://eol.org/schema/terms/hasParasite</rdfs:seeAlso>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002446 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002446">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002437"/>
<obo:IAO_0000112>Porifiera attaches to substrate</obo:IAO_0000112>
<obo:IAO_0000115>A biotic interaction relationship in which one partner is an organism and the other partner is inorganic. For example, the relationship between a sponge and the substrate to which is it anchored.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<oboInOwl:hasRelatedSynonym>semibiotically interacts with</oboInOwl:hasRelatedSynonym>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label>participates in a abiotic-biotic interaction with</rdfs:label>
<rdfs:seeAlso rdf:resource="http://dx.doi.org/10.1016/j.ecoinf.2014.08.005"/>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002447 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002447">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002436"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002215"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002481"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002400"/>
</owl:propertyChainAxiom>
<obo:IAO_0000116>Axiomatization to GO to be added later</obo:IAO_0000116>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000118>An interaction relation between x and y in which x catalyzes a reaction in which a phosphate group is added to y.</obo:IAO_0000118>
<rdfs:label>phosphorylates</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002448 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002448">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002436"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002566"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002327"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002211"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002333"/>
</owl:propertyChainAxiom>
<obo:IAO_0000115>Holds between molecular entities A and B where A can physically interact with B and in doing so regulates a process that B is capable of. For example, A and B may be gene products and binding of B by A regulates the kinase activity of B.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<oboInOwl:hasExactSynonym>molecularly controls</oboInOwl:hasExactSynonym>
<rdfs:label>activity directly regulates activity of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002449 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002449">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002448"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002327"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002630"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002333"/>
</owl:propertyChainAxiom>
<obo:IAO_0000115>Holds between molecular entities A and B where A can physically interact with B and in doing so negatively regulates a process that B is capable of. For example, A and B may be gene products and binding of B by A negatively regulates the kinase activity of B.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000118>inhibits</obo:IAO_0000118>
<oboInOwl:hasExactSynonym>molecularly decreases activity of</oboInOwl:hasExactSynonym>
<rdfs:label>activity directly negatively regulates activity of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002450 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002450">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002448"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002327"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002629"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002333"/>
</owl:propertyChainAxiom>
<obo:IAO_0000115>Holds between molecular entities A and B where A can physically interact with B and in doing so positively regulates a process that B is capable of. For example, A and B may be gene products and binding of B by A positively regulates the kinase activity of B.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000118>activates</obo:IAO_0000118>
<oboInOwl:hasExactSynonym>molecularly increases activity of</oboInOwl:hasExactSynonym>
<rdfs:label>activity directly positively regulates activity of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002451 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002451">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002321"/>
<obo:IAO_0000112>all dengue disease transmitted by some mosquito</obo:IAO_0000112>
<obo:IAO_0000115>A relationship that holds between a disease and organism</obo:IAO_0000115>
<obo:IAO_0000116>Add domain and range constraints</obo:IAO_0000116>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:label>transmitted by</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002452 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002452">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002200"/>
<obo:IAO_0000115>A relation that holds between a disease or an organism and a phenotype</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:label>has symptom</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002453 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002453">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002440"/>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000232>The term host is usually used for the larger (macro) of the two members of a symbiosis (GO)</obo:IAO_0000232>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label>host of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002454 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002454">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002440"/>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label>has host</rdfs:label>
<rdfs:seeAlso>http://eol.org/schema/terms/hasHost</rdfs:seeAlso>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002455 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002455">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002442"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002456"/>
<obo:IAO_0000112>Bees pollinate Flowers</obo:IAO_0000112>
<obo:IAO_0000116>This relation is intended to be used for biotic pollination - e.g. a bee pollinating a flowering plant. Some kinds of pollination may be semibiotic - e.g. wind can have the role of pollinator. We would use a separate relation for this.</obo:IAO_0000116>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000118>is subject of pollination interaction with</obo:IAO_0000118>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label>pollinates</rdfs:label>
<rdfs:seeAlso>http://eol.org/schema/terms/pollinates</rdfs:seeAlso>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002456 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002456">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002442"/>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000118>has polinator</obo:IAO_0000118>
<obo:IAO_0000118>is target of pollination interaction with</obo:IAO_0000118>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label>pollinated by</rdfs:label>
<rdfs:seeAlso>http://eol.org/schema/terms/hasPollinator</rdfs:seeAlso>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002457 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002457">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002438"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002469"/>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000232>Intended to be used when the target of the relation is not itself consumed, and does not have integral parts consumed, but provided nutrients in some other fashion.</obo:IAO_0000232>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label>acquires nutrients from</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002458 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002458">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002438"/>
<obo:IAO_0000115>inverse of preys on</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000118>has predator</obo:IAO_0000118>
<obo:IAO_0000118>is target of predation interaction with</obo:IAO_0000118>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/RO_0002259"/>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label>preyed upon by</rdfs:label>
<rdfs:seeAlso>http://eol.org/schema/terms/HasPredator</rdfs:seeAlso>
<rdfs:seeAlso>http://polytraits.lifewatchgreece.eu/terms/PRED</rdfs:seeAlso>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002459 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002459">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002574"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002460"/>
<obo:IAO_0000112>Anopheles is a vector for Plasmodium</obo:IAO_0000112>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000119>a is a vector for b if a carries and transmits an infectious pathogen b into another living organism</obo:IAO_0000119>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label>is vector for</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002460 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002460">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002459"/>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label>has vector</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002461 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002461">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000232>Experimental: relation used for defining interaction relations. An interaction relation holds when there is an interaction event with two partners. In a directional interaction, one partner is deemed the subject, the other the target</obo:IAO_0000232>
<rdfs:label>partner in</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002462 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002462">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002461"/>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000232>Experimental: relation used for defining interaction relations; the meaning of s 'subject participant in' p is determined by the type of p, where p must be a directional interaction process. For example, in a predator-prey interaction process the subject is the predator. We can imagine a reciprocal prey-predatory process with subject and object reversed.</obo:IAO_0000232>
<rdfs:label>subject participant in</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002463 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002463">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002461"/>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000232>Experimental: relation used for defining interaction relations; the meaning of s 'target participant in' p is determined by the type of p, where p must be a directional interaction process. For example, in a predator-prey interaction process the target is the prey. We can imagine a reciprocal prey-predatory process with subject and object reversed.</obo:IAO_0000232>
<rdfs:label>target participant in</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002464 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002464">
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000428"/>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000232>This property or its subproperties is not to be used directly. These properties exist as helper properties that are used to support OWL reasoning.</obo:IAO_0000232>
<rdfs:label>helper property</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002465 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002465">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002563"/>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:label>is symbiosis</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002466 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002466">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002465"/>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:label>is commensalism</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002467 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002467">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002465"/>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:label>is mutualism</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002468 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002468">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002465"/>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:label>is parasitism</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002469 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002469">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002438"/>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label>provides nutrients for</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002470 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002470">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002438"/>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000118>is subject of eating interaction with</obo:IAO_0000118>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label>eats</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002471 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002471">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002438"/>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000118>eaten by</obo:IAO_0000118>
<obo:IAO_0000118>is target of eating interaction with</obo:IAO_0000118>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label>is eaten by</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002472 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002472">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002616"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002558"/>
<obo:IAO_0000115>A relationship between a piece of evidence a and some entity b, where b is an information content entity, material entity or process, and
the a supports either the existence of b, or the truth value of b.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label>is evidence for</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002473 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002473">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<obo:IAO_0000112>'otolith organ' SubClassOf 'composed primarily of' some 'calcium carbonate'</obo:IAO_0000112>
<obo:IAO_0000115>x composed_primarily_of y if and only if more than half of the mass of x is made from y or units of the same type as y.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000119 rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/22293552"/>
<obo:RO_0001900 rdf:resource="http://purl.obolibrary.org/obo/RO_0001901"/>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label>composed primarily of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002476 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002476">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002258"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/GO_0005634"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/GO_0005634"/>
<obo:IAO_0000112>ABal nucleus child nucleus of ABa nucleus (in C elegans)</obo:IAO_0000112>
<obo:IAO_0000115>c is a child nucleus of d if and only if c and d are both nuclei and parts of cells c' and d', where c' is derived from d' by mitosis and the genetic material in c is a copy of the generic material in d</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000232>This relation is primarily used in the worm anatomy ontology for representing lineage at the level of nuclei. However, it is applicable to any organismal cell lineage.</obo:IAO_0000232>
<rdfs:label>child nucleus of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002477 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002477">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002476"/>
<obo:IAO_0000115>A child nucleus relationship in which the cells are part of a hermaphroditic organism</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:label>child nucleus of in hermaphrodite</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002478 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002478">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002476"/>
<obo:IAO_0000115>A child nucleus relationship in which the cells are part of a male organism</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:label>child nucleus of in male</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002479 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002479">
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000003"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000004"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000051"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000066"/>
</owl:propertyChainAxiom>
<obo:IAO_0000115>p has part that occurs in c if and only if there exists some p1, such that p has_part p1, and p1 occurs in c.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label>has part that occurs in</rdfs:label>
</owl:ObjectProperty>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/RO_0002479"/>
<owl:annotatedProperty rdf:resource="http://www.w3.org/2002/07/owl#propertyChainAxiom"/>
<owl:annotatedTarget rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000051"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000066"/>
</owl:annotatedTarget>
<obo:RO_0002581 rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</obo:RO_0002581>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/RO_0002480 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002480">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002436"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002215"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002482"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002400"/>
</owl:propertyChainAxiom>
<obo:IAO_0000115>An interaction relation between x and y in which x catalyzes a reaction in which one or more ubiquitin groups are added to y</obo:IAO_0000115>
<obo:IAO_0000116>Axiomatization to GO to be added later</obo:IAO_0000116>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:label>ubiquitinates</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002481 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002481">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002564"/>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:label>is kinase activity</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002482 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002482">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002564"/>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:label>is ubiquitination</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002485 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002485">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002170"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002486"/>
<obo:IAO_0000116>See notes for inverse relation</obo:IAO_0000116>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:label>receives input from</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002486 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002486">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002170"/>
<obo:IAO_0000116>This is an exploratory relation. The label is taken from the FMA. It needs aligned with the neuron-specific relations such as has postsynaptic terminal in.</obo:IAO_0000116>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:label>sends output to</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002487 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002487">
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000002"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000003"/>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000232>Do not use this relation directly. It is ended as a grouping for a diverse set of relations, typically connecting an anatomical entity to a biological process or developmental stage.</obo:IAO_0000232>
<rdfs:label>relation between structure and stage</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002488 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002488">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002490"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002496"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002488"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000050"/>
</owl:propertyChainAxiom>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002583"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000050"/>
</owl:propertyChainAxiom>
<obo:IAO_0000115>x existence starts during y if and only if the time point at which x starts is after or equivalent to the time point at which y starts and before or equivalent to the time point at which y ends. Formally: x existence starts during y iff a(x) >= a(y) & a(x) <= ?(y).</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:label>existence starts during</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002489 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002489">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002488"/>
<obo:IAO_0000115>x starts ends with y if and only if the time point at which x starts is equivalent to the time point at which y starts. Formally: x existence starts with y iff a(x) = a(y).</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:label>existence starts with</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002490 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002490">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002487"/>
<obo:IAO_0000115>x existence overlaps y if and only if either (a) the start of x is part of y or (b) the end of x is part of y. Formally: x existence starts and ends during y iff (a(x) >= a(y) & a(x) <= ?(y)) OR (?(x) <= ?(y) & ?(x) >= a(y))</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:comment>The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription.</rdfs:comment>
<rdfs:label>existence overlaps</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002491 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002491">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002488"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002492"/>
<obo:IAO_0000115>x existence starts and ends during y if and only if the start of x is part of y and the end of x is part of y. Formally: x existence starts and ends during y iff a(x) >= a(y) & a(x) <= ?(y) & ?(x) <= ?(y) & ?(x) >= a(y)</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:comment>The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription.</rdfs:comment>
<rdfs:label>existence starts and ends during</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002492 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002492">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002490"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002497"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002492"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000050"/>
</owl:propertyChainAxiom>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002593"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000050"/>
</owl:propertyChainAxiom>
<obo:IAO_0000115>x existence ends during y if and only if the time point at which x ends is before or equivalent to the time point at which y ends and after or equivalent to the point at which y starts. Formally: x existence ends during y iff ?(x) <= ?(y) and ?(x) >= a(y).</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:comment>The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription.</rdfs:comment>
<rdfs:label>existence ends during</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002493 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002493">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002492"/>
<obo:IAO_0000115>x existence ends with y if and only if the time point at which x ends is equivalent to the time point at which y ends. Formally: x existence ends with y iff ?(x) = ?(y).</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:comment>The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription.</rdfs:comment>
<rdfs:label>existence ends with</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002494 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002494">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002202"/>
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
<obo:IAO_0000115>x transformation of y if x is the immediate transformation of y, or is linked to y through a chain of transformation relationships</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:label>transformation of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002495 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002495">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002207"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002494"/>
<obo:IAO_0000115>x immediate transformation of y iff x immediately succeeds y temporally at a time boundary t, and all of the matter present in x at t is present in y at t, and all the matter in y at t is present in x at t</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:RO_0002575 rdf:resource="http://purl.obolibrary.org/obo/RO_0002494"/>
<rdfs:label>immediate transformation of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002496 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002496">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002487"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000050"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002496"/>
</owl:propertyChainAxiom>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002258"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002496"/>
</owl:propertyChainAxiom>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002496"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000050"/>
</owl:propertyChainAxiom>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002496"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000062"/>
</owl:propertyChainAxiom>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002496"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002082"/>
</owl:propertyChainAxiom>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002583"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000062"/>
<rdf:Description>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002583"/>
</rdf:Description>
</owl:propertyChainAxiom>
<obo:IAO_0000115>x existence starts during or after y if and only if the time point at which x starts is after or equivalent to the time point at which y starts. Formally: x existence starts during or after y iff a (x) >= a (y).</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:comment>The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription.</rdfs:comment>
<rdfs:label>existence starts during or after</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002497 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002497">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002487"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000050"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002497"/>
</owl:propertyChainAxiom>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002286"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002497"/>
</owl:propertyChainAxiom>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002497"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000050"/>
</owl:propertyChainAxiom>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002497"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000063"/>
</owl:propertyChainAxiom>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002497"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002082"/>
</owl:propertyChainAxiom>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002593"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000063"/>
<rdf:Description>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002593"/>
</rdf:Description>
</owl:propertyChainAxiom>
<obo:IAO_0000115>x existence ends during or before y if and only if the time point at which x ends is before or equivalent to the time point at which y ends.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:comment>The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription.</rdfs:comment>
<rdfs:label>existence ends during or before</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002500 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002500">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002595"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002608"/>
<obo:IAO_0000115>A relationship between a material entity and a process where the material entity has some causal role that influences the process</obo:IAO_0000115>
<obo:IAO_0000119 rdf:resource="http://purl.obolibrary.org/obo/ro/docs/causal-relations"/>
<rdfs:label>causal agent in</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002501 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002501">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002410"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000003"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000003"/>
<obo:IAO_0000115>p is causally related to q if and only if p or any part of p and q or any part of q are linked by a chain of events where each event pair is one of direct activation or direct inhibition. p may be upstream, downstream, part of or a container of q.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000119 rdf:resource="http://purl.obolibrary.org/obo/ro/docs/causal-relations"/>
<obo:IAO_0000232>Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect.</obo:IAO_0000232>
<rdfs:label>causal relation between processes</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002502 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002502">
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:label>depends on</rdfs:label>
<rdfs:seeAlso rdf:resource="http://purl.obolibrary.org/obo/BFO_0000169"/>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002503 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002503">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002502"/>
<obo:IAO_0000115>q towards e2 if and only if q is a relational quality such that q inheres-in some e, and e != e2 and q is dependent on e2</obo:IAO_0000115>
<obo:IAO_0000116>This relation is provided in order to support the use of relational qualities such as 'concentration of'; for example, the concentration of C in V is a quality that inheres in V, but pertains to C.</obo:IAO_0000116>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000119 rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/20064205"/>
<rdfs:label>towards</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002505 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002505">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
<obo:IAO_0000112>'lysine biosynthetic process via diaminopimelate' SubClassOf has_intermediate some diaminopimelate</obo:IAO_0000112>
<obo:IAO_0000115>p has intermediate c if and only if p has parts p1, p2 and p1 has output c, and p2 has input c</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000118>has intermediate product</obo:IAO_0000118>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label>has intermediate</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002506 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002506">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002410"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<obo:IAO_0000116>The intent is that the process branch of the causal property hierarchy is primary (causal relations hold between occurrents/processes), and that the material branch is defined in terms of the process branch</obo:IAO_0000116>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000119 rdf:resource="http://purl.obolibrary.org/obo/ro/docs/causal-relations"/>
<obo:IAO_0000232>Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect.</obo:IAO_0000232>
<rdfs:label>causal relation between material entities</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002507 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002507">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002509"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002559"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002508"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/RO_0002577"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<obo:IAO_0000112>A coral reef environment is determined by a particular coral reef</obo:IAO_0000112>
<obo:IAO_0000115>s determined by f if and only if s is a type of system, and f is a material entity that is part of s, such that f exerts a strong causal influence on the functioning of s, and the removal of f would cause the collapse of s.</obo:IAO_0000115>
<obo:IAO_0000116>The label for this relation is probably too general for its restricted use, where the domain is a system. It may be relabeled in future</obo:IAO_0000116>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000119 rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/24330602"/>
<obo:IAO_0000589>determined by (system to material entity)</obo:IAO_0000589>
<dc:creator>Chris Mungall</dc:creator>
<dc:creator>Pier Buttigieg</dc:creator>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label>determined by</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002508 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002508">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002566"/>
<obo:IAO_0000115>inverse of determined by</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000589>determines (material entity to system)</obo:IAO_0000589>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/RO_0002259"/>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label>determines</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002509 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002509">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002131"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002506"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/RO_0002577"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002507"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000050"/>
</owl:propertyChainAxiom>
<obo:IAO_0000115>s 'determined by part of' w if and only if there exists some f such that (1) s 'determined by' f and (2) f part_of w, or f=w.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label>determined by part of</rdfs:label>
</owl:ObjectProperty>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/RO_0002509"/>
<owl:annotatedProperty rdf:resource="http://www.w3.org/2002/07/owl#propertyChainAxiom"/>
<owl:annotatedTarget rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002507"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000050"/>
</owl:annotatedTarget>
<obo:RO_0002582 rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</obo:RO_0002582>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/RO_0002510 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002510">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002330"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002511"/>
<obo:IAO_0000115>x is transcribed from y if and only if x is synthesized from template y</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000119 rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">http://www.ncbi.nlm.nih.gov/pubmed/20226267</obo:IAO_0000119>
<rdfs:label>transcribed from</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002511 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002511">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002330"/>
<obo:IAO_0000115>inverse of transcribed from</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000119 rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">http://www.ncbi.nlm.nih.gov/pubmed/20226267</obo:IAO_0000119>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/RO_0002259"/>
<rdfs:label>transcribed to</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002512 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002512">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002330"/>
<obo:IAO_0000115>x is the ribosomal translation of y if and only if a ribosome reads x through a series of triplet codon-amino acid adaptor activities (GO:0030533) and produces y</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000119 rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">http://www.ncbi.nlm.nih.gov/pubmed/20226267</obo:IAO_0000119>
<rdfs:label>ribosomal translation of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002513 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002513">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002330"/>
<obo:IAO_0000115>inverse of ribosomal translation of</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000119 rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">http://www.ncbi.nlm.nih.gov/pubmed/20226267</obo:IAO_0000119>
<rdfs:label>ribosomally translates to</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002514 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002514">
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/RO_0002532"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/RO_0002532"/>
<obo:IAO_0000115>A relation that holds between two entities that have the property of being sequences or having sequences. </obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000119 rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">http://www.ncbi.nlm.nih.gov/pubmed/20226267</obo:IAO_0000119>
<obo:IAO_0000232>Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving cause and effect.</obo:IAO_0000232>
<obo:IAO_0000232>The domain and range of this relation include entities such as: information-bearing macromolecules such as DNA, or regions of these molecules; abstract information entities encoded as a linear sequence including text, abstract DNA sequences; Sequence features, entities that have a sequence or sequences. Note that these entities are not necessarily contiguous - for example, the mereological sum of exons on a genome of a particular gene.</obo:IAO_0000232>
<cito:citesAsAuthority rdf:resource="http://biorxiv.org/content/early/2014/06/27/006650.abstract"/>
<rdfs:label>sequentially related to</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002515 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002515">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002527"/>
<obo:IAO_0000112>Every UTR is adjacent to a CDS of the same transcript</obo:IAO_0000112>
<obo:IAO_0000112>Two consecutive DNA residues are sequentially adjacent</obo:IAO_0000112>
<obo:IAO_0000112>Two exons on a processed transcript that were previously connected by an intron are adjacent</obo:IAO_0000112>
<obo:IAO_0000115>x is sequentially adjacent to y iff x and y do not overlap and if there are no base units intervening between x and y</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000119 rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">http://www.ncbi.nlm.nih.gov/pubmed/20226267</obo:IAO_0000119>
<cito:citesAsAuthority rdf:resource="http://biorxiv.org/content/early/2014/06/27/006650.abstract"/>
<rdfs:label>sequentially adjacent to</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002516 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002516">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002524"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002517"/>
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
<obo:IAO_0000112>Every CDS has as a start sequence the start codon for that transcript</obo:IAO_0000112>
<obo:IAO_0000115>x has start sequence y if the start of x is identical to the start of y, and x has y as a subsequence</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000118>started by</obo:IAO_0000118>
<obo:IAO_0000119 rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">http://www.ncbi.nlm.nih.gov/pubmed/20226267</obo:IAO_0000119>
<cito:citesAsAuthority rdf:resource="http://biorxiv.org/content/early/2014/06/27/006650.abstract"/>
<rdfs:label>has start sequence</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002517 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002517">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002525"/>
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
<obo:IAO_0000115>inverse of has start sequence</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000118>starts</obo:IAO_0000118>
<obo:IAO_0000119 rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">http://www.ncbi.nlm.nih.gov/pubmed/20226267</obo:IAO_0000119>
<cito:citesAsAuthority rdf:resource="http://biorxiv.org/content/early/2014/06/27/006650.abstract"/>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/RO_0002259"/>
<rdfs:label>is start sequence of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002518 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002518">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002524"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002519"/>
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
<obo:IAO_0000112>Every CDS has as an end sequence the stop codon for that transcript (note this follows from the SO definition of CDS, in which stop codons are included)</obo:IAO_0000112>
<obo:IAO_0000115>x has end sequence y if the end of x is identical to the end of y, and x has y as a subsequence</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000118>ended by</obo:IAO_0000118>
<obo:IAO_0000119 rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">http://www.ncbi.nlm.nih.gov/pubmed/20226267</obo:IAO_0000119>
<cito:citesAsAuthority rdf:resource="http://biorxiv.org/content/early/2014/06/27/006650.abstract"/>
<rdfs:label>has end sequence</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002519 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002519">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002525"/>
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
<obo:IAO_0000115>inverse of has end sequence</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000118>ends</obo:IAO_0000118>
<obo:IAO_0000119 rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">http://www.ncbi.nlm.nih.gov/pubmed/20226267</obo:IAO_0000119>
<cito:citesAsAuthority rdf:resource="http://biorxiv.org/content/early/2014/06/27/006650.abstract"/>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/RO_0002259"/>
<rdfs:label>is end sequence of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002520 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002520">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002524"/>
<obo:IAO_0000115>x is a consecutive sequence of y iff x has subsequence y, and all the parts of x are made of zero or more repetitions of y or sequences as the same type as y.</obo:IAO_0000115>
<obo:IAO_0000116>In the SO paper, this was defined as an instance-type relation</obo:IAO_0000116>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000119 rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">http://www.ncbi.nlm.nih.gov/pubmed/20226267</obo:IAO_0000119>
<cito:citesAsAuthority rdf:resource="http://biorxiv.org/content/early/2014/06/27/006650.abstract"/>
<rdfs:label>is consecutive sequence of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002521 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002521">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002514"/>
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#SymmetricProperty"/>
<obo:IAO_0000112>Human Shh and Mouse Shh are sequentially aligned, by cirtue of the fact that they derive from the same ancestral sequence.</obo:IAO_0000112>
<obo:IAO_0000115>x is sequentially aligned with if a significant portion bases of x and y correspond in terms of their base type and their relative ordering</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<cito:citesAsAuthority rdf:resource="http://biorxiv.org/content/early/2014/06/27/006650.abstract"/>
<rdfs:label>is sequentially aligned with</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002522 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002522">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002514"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002523"/>
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
<obo:IAO_0000112>The genomic exons of a transcript bound the sequence of the genomic introns of the same transcript (but the introns are not subsequences of the exons)</obo:IAO_0000112>
<obo:IAO_0000115>x bounds the sequence of y iff the upstream-most part of x is upstream of or coincident with the upstream-most part of y, and the downstream-most part of x is downstream of or coincident with the downstream-most part of y</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<cito:citesAsAuthority rdf:resource="http://biorxiv.org/content/early/2014/06/27/006650.abstract"/>
<rdfs:label>bounds sequence of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002523 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002523">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002514"/>
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
<obo:IAO_0000115>inverse of bounds sequence of</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<cito:citesAsAuthority rdf:resource="http://biorxiv.org/content/early/2014/06/27/006650.abstract"/>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/RO_0002259"/>
<rdfs:label>is bound by sequence of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002524 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002524">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002522"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002526"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002525"/>
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
<obo:IAO_0000115>x has subsequence y iff all of the sequence parts of x are sequence parts of y</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000118>contains</obo:IAO_0000118>
<obo:IAO_0000119 rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">http://www.ncbi.nlm.nih.gov/pubmed/20226267</obo:IAO_0000119>
<cito:citesAsAuthority rdf:resource="http://biorxiv.org/content/early/2014/06/27/006650.abstract"/>
<rdfs:label>has subsequence</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002525 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002525">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002523"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002526"/>
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
<obo:IAO_0000115>inverse of has subsequence</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000118>contained by</obo:IAO_0000118>
<cito:citesAsAuthority rdf:resource="http://biorxiv.org/content/early/2014/06/27/006650.abstract"/>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/RO_0002259"/>
<rdfs:label>is subsequence of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002526 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002526">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002131"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002514"/>
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#SymmetricProperty"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002524"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002525"/>
</owl:propertyChainAxiom>
<obo:IAO_0000115>x overlaps the sequence of x if and only if x has a subsequence z and z is a subsequence of y.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<cito:citesAsAuthority rdf:resource="http://biorxiv.org/content/early/2014/06/27/006650.abstract"/>
<rdfs:label>overlaps sequence of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002527 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002527">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002514"/>
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#SymmetricProperty"/>
<obo:IAO_0000115>x does not overlaps the sequence of x if and only if there is no z such that x has a subsequence z and z is a subsequence of y.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000118>disconnected from</obo:IAO_0000118>
<cito:citesAsAuthority rdf:resource="http://biorxiv.org/content/early/2014/06/27/006650.abstract"/>
<rdfs:label>does not overlap sequence of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002528 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002528">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002527"/>
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
<obo:IAO_0000115>inverse of downstream of sequence of</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<cito:citesAsAuthority rdf:resource="http://biorxiv.org/content/early/2014/06/27/006650.abstract"/>
<rdfs:label>is upstream of sequence of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002529 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002529">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002527"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002529"/>
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
<obo:IAO_0000115>x is downstream of the sequence of y iff either (1) x and y have sequence units, and all units of x are downstream of all units of y, or (2) x and y are sequence units, and x is either immediately downstream of y, or transitively downstream of y.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<cito:citesAsAuthority rdf:resource="http://biorxiv.org/content/early/2014/06/27/006650.abstract"/>
<rdfs:label>is downstream of sequence of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002530 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002530">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002515"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002529"/>
<obo:IAO_0000112>A 3'UTR is immediately downstream of the sequence of the CDS from the same monocistronic transcript</obo:IAO_0000112>
<obo:IAO_0000115>x is immediately downstream of the sequence of y iff either (1) x and y have sequence units, and all units of x are downstream of all units of y, and x is sequentially adjacent to y, or (2) x and y are sequence units, in which case the immediately downstream relation is primitive and defined by context: for DNA bases, y would be adjacent and 5' to y</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:RO_0002575 rdf:resource="http://purl.obolibrary.org/obo/RO_0002529"/>
<cito:citesAsAuthority rdf:resource="http://biorxiv.org/content/early/2014/06/27/006650.abstract"/>
<rdfs:label>is immediately downstream of sequence of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002531 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002531">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002515"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002528"/>
<obo:IAO_0000112>A 5'UTR is immediately upstream of the sequence of the CDS from the same monocistronic transcript</obo:IAO_0000112>
<obo:IAO_0000115>inverse of immediately downstream of</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<cito:citesAsAuthority rdf:resource="http://biorxiv.org/content/early/2014/06/27/006650.abstract"/>
<rdfs:label>is immediately upstream of sequence of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002551 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002551">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002576"/>
<obo:IAO_0000112>Forelimb SubClassOf has_skeleton some 'Forelimb skeleton'</obo:IAO_0000112>
<obo:IAO_0000115>A relation between a segment or subdivision of an organism and the maximal subdivision of material entities that provides structural support for that segment or subdivision.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000118>has supporting framework</obo:IAO_0000118>
<obo:IAO_0000232>The skeleton of a structure may be a true skeleton (for example, the bony skeleton of a hand) or any kind of support framework (the hydrostatic skeleton of a sea star, the exoskeleton of an insect, the cytoskeleton of a cell).</obo:IAO_0000232>
<rdfs:label>has skeleton</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002552 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002552">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002295"/>
<obo:IAO_0000115>p results in the end of s if p results in a change of state in s whereby s either ceases to exist, or s becomes functionally impaired or s has its fate committed such that it is put on a path to be degraded.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:label>results in ending of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002553 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002553">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002454"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002554"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002444"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002444"/>
</owl:propertyChainAxiom>
<obo:IAO_0000115>x is a hyperparasite of y iff x is a parasite of a parasite of the target organism y</obo:IAO_0000115>
<obo:IAO_0000116>Note that parasite-of is a diret relationship, so hyperparasite-of is not considered a sub-relation, even though hyperparasitism can be considered a form of parasitism</obo:IAO_0000116>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000119>http://eol.org/schema/terms/hyperparasitoidOf</obo:IAO_0000119>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Hyperparasite</obo:IAO_0000119>
<oboInOwl:hasRelatedSynonym>epiparasite of</oboInOwl:hasRelatedSynonym>
<oboInOwl:hasRelatedSynonym>hyperparasitoid of</oboInOwl:hasRelatedSynonym>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label>hyperparasite of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002554 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002554">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002453"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002445"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002445"/>
</owl:propertyChainAxiom>
<obo:IAO_0000115>inverse of hyperparasite of</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<oboInOwl:hasRelatedSynonym>has epiparasite</oboInOwl:hasRelatedSynonym>
<oboInOwl:hasRelatedSynonym>has hyperparasite</oboInOwl:hasRelatedSynonym>
<oboInOwl:hasRelatedSynonym>hyperparasitoidized by</oboInOwl:hasRelatedSynonym>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/RO_0002259"/>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label>hyperparasitized by</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002555 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002555">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002574"/>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000119>http://en.wikipedia.org/wiki/Allelopathy</obo:IAO_0000119>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label>allelopath of</rdfs:label>
<rdfs:seeAlso>http://eol.org/schema/terms/allelopathyYes</rdfs:seeAlso>
<rdfs:seeAlso>x is an allelopath of y iff xis an organism produces one or more biochemicals that influence the growth, survival, and reproduction of y</rdfs:seeAlso>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002556 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002556">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002454"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002557"/>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label>pathogen of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002557 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002557">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002453"/>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label>has pathogen</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002558 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002558">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002616"/>
<obo:IAO_0000115>inverse of is evidence for</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000119 rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/25052702"/>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/RO_0002259"/>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:comment>x has evidence y iff , x is an information content entity, material entity or process, and y supports either the existence of x, or the truth value of x.</rdfs:comment>
<rdfs:label>has evidence</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002559 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002559">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002506"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002566"/>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000119 rdf:resource="http://purl.obolibrary.org/obo/ro/docs/causal-relations"/>
<obo:IAO_0000589>causally influenced by (material entity to material entity)</obo:IAO_0000589>
<rdfs:label>causally influenced by</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002563 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002563">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002464"/>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:label>interaction relation helper property</rdfs:label>
<rdfs:seeAlso rdf:resource="http://ontologydesignpatterns.org/wiki/Submissions:N-Ary_Relation_Pattern_%28OWL_2%29"/>
<foaf:page rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://github.com/oborel/obo-relations/wiki/InteractionRelations</foaf:page>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002564 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002564">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002563"/>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:label>molecular interaction relation helper property</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002565 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002565">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
<obo:IAO_0000115>Holds between p and c when p is locomotion process and the outcome of this process is the change of location of c</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000232></obo:IAO_0000232>
<rdfs:label>results in movement of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002566 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002566">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002506"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002327"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002411"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002233"/>
</owl:propertyChainAxiom>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002327"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002411"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002333"/>
</owl:propertyChainAxiom>
<obo:IAO_0000115>Holds between materal entities a and b if the activity of a is causally upstream of the activity of b, or causally upstream of a an activity that modifies b</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000119 rdf:resource="http://purl.obolibrary.org/obo/ro/docs/causal-relations"/>
<obo:IAO_0000589>causally influences (material entity to material entity)</obo:IAO_0000589>
<rdfs:label>causally influences</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002567 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002567">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002328"/>
<obo:IAO_0000115>A relation that holds between elements of a musculoskeletal system or its analogs.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000232>Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving the biomechanical processes.</obo:IAO_0000232>
<rdfs:label>biomechanically related to</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002568 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002568">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002567"/>
<obo:IAO_0000115>m1 has_muscle_antagonist m2 iff m1 has_muscle_insertion s, m2 has_muscle_insection s, m1 acts in opposition to m2, and m2 is responsible for returning the structure to its initial position.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000119>Wikipedia:Antagonist_(muscle)</obo:IAO_0000119>
<rdfs:label>has muscle antagonist</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002569 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002569">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002375"/>
<obo:IAO_0000115>inverse of branching part of</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/RO_0002259"/>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label>has branching part</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002570 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002570">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002131"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<obo:IAO_0000115>x is a conduit for y iff y overlaps through the lumen_of of x, and y has parts on either side of the lumen of x.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000119>UBERON:cjm</obo:IAO_0000119>
<obo:IAO_0000232>This relation holds between a thing with a 'conduit' (e.g. a bone foramen) and a 'conduee' (for example, a nerve) such that at the time the relationship holds, the conduee has two ends sticking out either end of the conduit. It should therefore note be used for objects that move through the conduit but whose spatial extent does not span the passage. For example, it would not be used for a mountain that contains a long tunnel through which trains pass. Nor would we use it for a digestive tract and objects such as food that pass through.</obo:IAO_0000232>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label>conduit for</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002571 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002571">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<obo:IAO_0000115>x lumen_of y iff x is the space or substance that is part of y and does not cross any of the inner membranes or boundaries of y that is maximal with respect to the volume of the convex hull.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000119>GOC:cjm</obo:IAO_0000119>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label>lumen of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002572 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002572">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002571"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000141"/>
<obo:IAO_0000115>s is luminal space of x iff s is lumen_of x and s is an immaterial entity</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label>luminal space of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002573 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002573">
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/PATO_0000001"/>
<obo:IAO_0000115>A relation that holds between an attribute or a qualifier and another attribute.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000119 rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/20064205"/>
<obo:IAO_0000232>This relation is intended to be used in combination with PATO, to be able to refine PATO quality classes using modifiers such as 'abnormal' and 'normal'. It has yet to be formally aligned into an ontological framework; it's not clear what the ontological status of the "modifiers" are.</obo:IAO_0000232>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label>has modifier</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002574 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002574">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002437"/>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label>participates in a biotic-biotic interaction with</rdfs:label>
<rdfs:seeAlso rdf:resource="http://dx.doi.org/10.1016/j.ecoinf.2014.08.005"/>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002576 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002576">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/CARO_0000003"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/CARO_0000003"/>
<obo:IAO_0000115>inverse of has skeleton</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/RO_0002259"/>
<rdfs:label>skeleton of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002578 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002578">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002211"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002412"/>
<obo:IAO_0000115>Process(P1) directly regulates process(P2) iff: P1 regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding regulates the kinase activity (P2) of protein B then P1 directly regulates P2.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000119 rdf:resource="http://purl.obolibrary.org/obo/ro/docs/causal-relations"/>
<obo:IAO_0000589>directly regulates (processual)</obo:IAO_0000589>
<obo:RO_0002575 rdf:resource="http://purl.obolibrary.org/obo/RO_0002211"/>
<rdfs:label>directly regulates</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002583 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002583">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002487"/>
<obo:IAO_0000115>x existence starts at point y if and only if the time point at which x starts is equivalent to the time point at which y ends.</obo:IAO_0000115>
<rdfs:label>existence starts at point</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002584 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002584">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002328"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002595"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000051"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002215"/>
</owl:propertyChainAxiom>
<obo:IAO_0000112>gland SubClassOf 'has part structure that is capable of' some 'secretion by cell'</obo:IAO_0000112>
<obo:IAO_0000115>s 'has part structure that is capable of' p if and only if there exists some part x such that s 'has part' x and x 'capable of' p</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:label>has part structure that is capable of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002585 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002585">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002295"/>
<obo:IAO_0000116>p 'results in closure of' c if and only if p is a developmental process and p results in a state of c changing from open to closed.</obo:IAO_0000116>
<rdfs:label>results in closure of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002586 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002586">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002233"/>
<obo:IAO_0000115>p results in breakdown of c if and only if the execution of p leads to c no longer being present at the end of p</obo:IAO_0000115>
<rdfs:label>results in breakdown of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002587 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002587">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002297"/>
<rdfs:label>results in synthesis of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002588 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002588">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002297"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002592"/>
<rdfs:label>results in assembly of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002589 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002589">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002586"/>
<obo:IAO_0000115>p results in catabolism of c if and only if p is a catabolic process, and the execution of p results in c being broken into smaller parts with energy being released.</obo:IAO_0000115>
<rdfs:label>results in catabolism of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002590 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002590">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002586"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002592"/>
<rdfs:label>results in disassembly of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002591 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002591">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002233"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002592"/>
<rdfs:label>results in remodeling of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002592 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002592">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0000057"/>
<obo:IAO_0000115>p results in organization of c iff p results in the assembly, arrangement of constituent parts, or disassembly of c</obo:IAO_0000115>
<rdfs:label>results in organization of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002593 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002593">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002487"/>
<obo:IAO_0000115>x existence starts at point y if and only if the time point at which x starts is equivalent to the time point at which y ends.</obo:IAO_0000115>
<rdfs:label>existence ends at point</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002595 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002595">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002410"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
<obo:IAO_0000115>A relationship that holds between a material entity and a process in which causality is involved, with either the material entity or some part of the material entity exerting some influence over the process, or the process influencing some aspect of the material entity.</obo:IAO_0000115>
<obo:IAO_0000116>Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect.</obo:IAO_0000116>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000119 rdf:resource="http://purl.obolibrary.org/obo/ro/docs/causal-relations"/>
<rdfs:label>causal relation between material entity and a process</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002596 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002596">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002500"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002215"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002211"/>
</owl:propertyChainAxiom>
<obo:IAO_0000112>pyrethroid -> growth</obo:IAO_0000112>
<obo:IAO_0000115>Holds between c and p if and only if c is capable of some activity a, and a regulates p.</obo:IAO_0000115>
<obo:IAO_0000119 rdf:resource="http://purl.obolibrary.org/obo/ro/docs/causal-relations"/>
<rdfs:label>capable of regulating</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002597 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002597">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002596"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002215"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002212"/>
</owl:propertyChainAxiom>
<obo:IAO_0000115>Holds between c and p if and only if c is capable of some activity a, and a negatively regulates p.</obo:IAO_0000115>
<obo:IAO_0000119 rdf:resource="http://purl.obolibrary.org/obo/ro/docs/causal-relations"/>
<rdfs:label>capable of negatively regulating</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002598 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002598">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002596"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002215"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002213"/>
</owl:propertyChainAxiom>
<obo:IAO_0000112>renin -> arteriolar smooth muscle contraction</obo:IAO_0000112>
<obo:IAO_0000115>Holds between c and p if and only if c is capable of some activity a, and a positively regulates p.</obo:IAO_0000115>
<obo:IAO_0000119 rdf:resource="http://purl.obolibrary.org/obo/ro/docs/causal-relations"/>
<rdfs:label>capable of positively regulating</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002599 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002599">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002597"/>
<obo:IAO_0000112>pazopanib -> pathological angiogenesis</obo:IAO_0000112>
<obo:IAO_0000115>Holds between a material entity c and a pathological process p if and only if c is capable of some activity a, where a inhibits p.</obo:IAO_0000115>
<obo:IAO_0000118>treats</obo:IAO_0000118>
<obo:IAO_0000119 rdf:resource="http://purl.obolibrary.org/obo/ro/docs/causal-relations"/>
<obo:IAO_0000232>The entity c may be a molecular entity with a drug role, or it could be some other entity used in a therapeutic context, such as a hyperbaric chamber.</obo:IAO_0000232>
<rdfs:label>capable of inhibiting or preventing pathological process</rdfs:label>
</owl:ObjectProperty>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://purl.obolibrary.org/obo/RO_0002599"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000118"/>
<owl:annotatedTarget>treats</owl:annotatedTarget>
<rdfs:comment>Usage of the term 'treats' applies when we believe there to be a an inhibitory relationship</rdfs:comment>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/RO_0002600 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002600">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002598"/>
<obo:IAO_0000112>benzene -> cancer [CHEBI]</obo:IAO_0000112>
<obo:IAO_0000115>Holds between a material entity c and a pathological process p if and only if c is capable of some activity a, where a negatively regulates p.</obo:IAO_0000115>
<obo:IAO_0000118>causes disease</obo:IAO_0000118>
<obo:IAO_0000119 rdf:resource="http://purl.obolibrary.org/obo/ro/docs/causal-relations"/>
<rdfs:label>capable of upregulating or causing pathological process</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002606 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002606">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002599"/>
<obo:IAO_0000115>c is a substance that treats d if c is a material entity (such as a small molecule or compound) and d is a pathological process, phenotype or disease, and c is capable of some activity that negative regulates or decreases the magnitude of d.</obo:IAO_0000115>
<obo:IAO_0000118>treats</obo:IAO_0000118>
<obo:IAO_0000119 rdf:resource="http://purl.obolibrary.org/obo/ro/docs/causal-relations"/>
<rdfs:label>is substance that treats</rdfs:label>
<rdfs:seeAlso rdf:resource="https://code.google.com/p/obo-relations/issues/detail?id=46"/>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002607 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002607">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002610"/>
<obo:IAO_0000115>c is marker for d iff the presence or occurrence of d is correlated with the presence of occurrence of c, and the observation of c is used to infer the presence or occurrence of d. Note that this does not imply that c and d are in a direct causal relationship, as it may be the case that there is a third entity e that stands in a direct causal relationship with c and d.</obo:IAO_0000115>
<obo:IAO_0000116>May be ceded to OBI</obo:IAO_0000116>
<rdfs:label>is marker for</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002608 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002608">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002410"/>
<obo:IAO_0000115>Inverse of 'causal agent in'</obo:IAO_0000115>
<obo:IAO_0000119 rdf:resource="http://purl.obolibrary.org/obo/ro/docs/causal-relations"/>
<rdfs:label>has causal agent</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002609 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002609">
<obo:IAO_0000115>A relationship that holds between two entities, where the relationship holds based on the presence or absence of statistical dependence relationship. The entities may be statistical variables, or they may be other kinds of entities such as diseases, chemical entities or processes.</obo:IAO_0000115>
<obo:IAO_0000232>Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect.</obo:IAO_0000232>
<rdfs:label>related via dependence to</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002610 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002610">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002609"/>
<obo:IAO_0000115>A relationship that holds between two entities, where the entities exhibit a statistical dependence relationship. The entities may be statistical variables, or they may be other kinds of entities such as diseases, chemical entities or processes.</obo:IAO_0000115>
<obo:IAO_0000232>Groups both positive and negative correlation</obo:IAO_0000232>
<rdfs:label>correlated with</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002614 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002614">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002616"/>
<obo:IAO_0000112>An instance of a sequence similarity evidence (ECO:0000044) that uses a homologous sequence UniProtKB:P12345 as support.</obo:IAO_0000112>
<obo:IAO_0000115>A relationship between a piece of evidence and an entity that plays a role in supporting that evidence.</obo:IAO_0000115>
<rdfs:comment>In the Gene Ontology association model, this corresponds to the With/From field</rdfs:comment>
<rdfs:label>is evidence with support from</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002615 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002615">
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0003301"/>
<obo:IAO_0000115>Inverse of is-model-of</obo:IAO_0000115>
<rdfs:label>has model</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002616 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002616">
<rdfs:label>related via evidence or inference to</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002618 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002618">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002574"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002619"/>
<rdfs:label>visits</rdfs:label>
<rdfs:seeAlso rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://github.com/oborel/obo-relations/issues/74</rdfs:seeAlso>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002619 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002619">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002574"/>
<rdfs:label>visited by</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002622 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002622">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002618"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002623"/>
<rdfs:label>visits flowers of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002623 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002623">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002619"/>
<rdfs:label>has flowers visited by</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002624 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002624">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002444"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002618"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002625"/>
<rdfs:label>lays eggs in</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002625 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002625">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002445"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002619"/>
<rdfs:label>has eggs laid in by</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002626 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002626">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002574"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002627"/>
<obo:IAO_0000119>https://github.com/jhpoelen/eol-globi-data/issues/143</obo:IAO_0000119>
<rdfs:label>kills</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002627 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002627">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002574"/>
<rdfs:label>is killed by</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002629 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002629">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002213"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002578"/>
<obo:IAO_0000115>Process(P1) directly postively regulates process(P2) iff: P1 positively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding positively regulates the kinase activity (P2) of protein B then P1 directly positively regulates P2.</obo:IAO_0000115>
<obo:IAO_0000119 rdf:resource="http://purl.obolibrary.org/obo/ro/docs/causal-relations"/>
<obo:IAO_0000589>directly positively regulates (process to process)</obo:IAO_0000589>
<rdfs:label>directly positively regulates</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002630 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002630">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002212"/>
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002578"/>
<obo:IAO_0000115>Process(P1) directly negatively regulates process(P2) iff: P1 negatively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding negatively regulates the kinase activity (P2) of protein B then P1 directly negatively regulates P2.</obo:IAO_0000115>
<obo:IAO_0000119 rdf:resource="http://purl.obolibrary.org/obo/ro/docs/causal-relations"/>
<obo:IAO_0000589>directly negatively regulates (process to process)</obo:IAO_0000589>
<rdfs:label>directly negatively regulates</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002632 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002632">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002444"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002633"/>
<obo:IAO_0000115>A sub-relation of parasite-of in which the parasite lives on or in the integumental system of the host</obo:IAO_0000115>
<obo:IAO_0000119 rdf:resource="https://en.wikipedia.org/wiki/Parasitism#Types"/>
<rdfs:label>ectoparasite of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002633 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002633">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002445"/>
<obo:IAO_0000115>inverse of ectoparasite of</obo:IAO_0000115>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/RO_0002259"/>
<rdfs:label>has ectoparasite</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002634 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002634">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002444"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002635"/>
<obo:IAO_0000119 rdf:resource="https://en.wikipedia.org/wiki/Parasitism#Types"/>
<obo:IAO_0000119>A sub-relation of parasite-of in which the parasite lives inside the host, beneath the integumental system</obo:IAO_0000119>
<oboInOwl:hasRelatedSynonym>lives inside of</oboInOwl:hasRelatedSynonym>
<rdfs:label>endoparasite of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002635 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002635">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002445"/>
<rdfs:label>has endoparasite</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002636 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002636">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002444"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002637"/>
<obo:IAO_0000115>A sub-relation of parasite-of in which the parasite is partially an endoparasite and partially an ectoparasite</obo:IAO_0000115>
<rdfs:label>mesoparasite of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002637 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002637">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002445"/>
<obo:IAO_0000115>inverse of mesoparasite of</obo:IAO_0000115>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/RO_0002259"/>
<rdfs:label>has mesoparasite</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002638 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002638">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002634"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002639"/>
<obo:IAO_0000115>A sub-relation of endoparasite-of in which the parasite inhabits the spaces between host cells.</obo:IAO_0000115>
<obo:IAO_0000119 rdf:resource="https://en.wikipedia.org/wiki/Parasitism#Types"/>
<rdfs:label>intercellular endoparasite of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002639 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002639">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002635"/>
<obo:IAO_0000115>inverse of intercellular endoparasite of</obo:IAO_0000115>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/RO_0002259"/>
<rdfs:label>has intercellular endoparasite</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002640 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002640">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002634"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002641"/>
<obo:IAO_0000115>A sub-relation of endoparasite-of in which the parasite inhabits host cells.</obo:IAO_0000115>
<obo:IAO_0000119 rdf:resource="https://en.wikipedia.org/wiki/Parasitism#Types"/>
<rdfs:label>intracellular endoparasite of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002641 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002641">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002635"/>
<obo:IAO_0000115>inverse of intracellular endoparasite of</obo:IAO_0000115>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/RO_0002259"/>
<rdfs:label>has intracellular endoparasite</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0003000 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0003000">
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0003001"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
</rdf:Description>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002234"/>
</owl:propertyChainAxiom>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">a produces b if some process that occurs_in a has_output b, where a and b are material entities. Examples: hybridoma cell line produces monoclonal antibody reagent; chondroblast produces avascular GAG-rich matrix.</obo:IAO_0000115>
<obo:IAO_0000117>Melissa Haendel</obo:IAO_0000117>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Note that this definition doesn't quite distinguish the output of a transformation process from a production process, which is related to the identity/granularity issue.</rdfs:comment>
<rdfs:label xml:lang="en">produces</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0003001 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0003001">
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<obo:IAO_0000115>a produced_by b iff some process that occurs_in b has_output a.</obo:IAO_0000115>
<obo:IAO_0000117>Melissa Haendel</obo:IAO_0000117>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<rdfs:label xml:lang="en">produced by</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0003002 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0003002">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002449"/>
<obo:IAO_0000115>Holds between protein a (a transcription factor) and DNA element b if and only if a diminishes the process of transcription of b.</obo:IAO_0000115>
<obo:IAO_0000116>Logical axioms to be added after the relevant branch of GO is MIREOTed in</obo:IAO_0000116>
<rdfs:label>represses expression of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0003003 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0003003">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002450"/>
<obo:IAO_0000115>Holds between protein a (a transcription factor) and DNA element b if and only if a activates the process of transcription of b.</obo:IAO_0000115>
<obo:IAO_0000116>Logical axioms to be added after the relevant branch of GO is MIREOTed in</obo:IAO_0000116>
<rdfs:label>increases expression of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0003301 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0003301">
<obo:IAO_0000115>Relation between a research artifact and an entity it is used to study, in virtue of its replicating or approximating features of the studied entity.</obo:IAO_0000115>
<obo:IAO_0000116>To Do: decide on scope of this relation - inclusive of computational models in domain, or only physical models? Restricted to linking biological systems and phenomena? Inclusive of only diseases in range, or broader?</obo:IAO_0000116>
<obo:IAO_0000117>Matthew Brush</obo:IAO_0000117>
<rdfs:comment>The driving use case for this relation was to link a biological model system such as a cell line or model organism to a disease it is used to investigate, in virtue of the model system exhibiting features similar to that of the disease of interest.</rdfs:comment>
<rdfs:label xml:lang="en">is model of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0003302 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0003302">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002410"/>
<obo:IAO_0000112>The genetic variant 'NM_007294.3(BRCA1):c.110C>A (p.Thr37Lys)' casues or contributes to the disease 'familial breast-ovarian cancer'.
An environment of exposure to arsenic causes or contributes to the phenotype of patchy skin hyperpigmentation, and the disease 'skin cancer'.</obo:IAO_0000112>
<obo:IAO_0000115>A relationship between an entity (e.g. a genotype, genetic variation, chemical, or environmental exposure) and a condition (a phenotype or disease), where the entity has some causal or contributing role that influences the condition.</obo:IAO_0000115>
<obo:IAO_0000116>Note that relationships of phenotypes to organisms/strains that bear them, or diseases they are manifest in, should continue to use RO:0002200 ! 'has phenotype' and RO:0002201 ! 'phenotype of'.</obo:IAO_0000116>
<rdfs:comment>Genetic variations can span any level of granularity from a full genome or genotype to an individual gene or sequence alteration. These variations can be represented at the physical level (DNA/RNA macromolecules or their parts, as in the ChEBI ontology and Molecular Sequence Ontology) or at the abstract level (generically dependent continuant sequence features that are carried by these macromolecules, as in the Sequence Ontology and Genotype Ontology). The causal relations in this hierarchy can be used in linking either physical or abstract genetic variations to phenotypes or diseases they cause or contribute to.
Environmental exposures include those imposed by natural environments, experimentally applied conditions, or clinical interventions.</rdfs:comment>
<rdfs:label xml:lang="en">causes or contributes to condition</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0003303 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0003303">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0003302"/>
<obo:IAO_0000115>A relationship between an entity (e.g. a genotype, genetic variation, chemical, or environmental exposure) and a condition (a phenotype or disease), where the entity has some causal role for the condition.</obo:IAO_0000115>
<rdfs:label xml:lang="en">causes condition</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0003304 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0003304">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0003302"/>
<obo:IAO_0000115>A relationship between an entity (e.g. a genotype, genetic variation, chemical, or environmental exposure) and a condition (a phenotype or disease), where the entity has some contributing role that influences the condition.</obo:IAO_0000115>
<rdfs:label xml:lang="en">contributes to condition</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0003305 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0003305">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0003304"/>
<obo:IAO_0000115>A relationship between an entity (e.g. a genotype, genetic variation, chemical, or environmental exposure) and a condition (a phenotype or disease), where the entity influences the severity with which a condition manifests in an individual.</obo:IAO_0000115>
<obo:IAO_0000118>contributes to expressivity of condition</obo:IAO_0000118>
<rdfs:label xml:lang="en">contributes to severity of condition</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0003306 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0003306">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0003304"/>
<obo:IAO_0000115>A relationship between an entity (e.g. a genotype, genetic variation, chemical, or environmental exposure) and a condition (a phenotype or disease), where the entity influences the frequency of the condition in a population.</obo:IAO_0000115>
<obo:IAO_0000118>contributes to penetrance of condition</obo:IAO_0000118>
<rdfs:label xml:lang="en">contributes to frequency of condition</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0003307 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0003307">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0003305"/>
<obo:IAO_0000115>A relationship between an entity (e.g. a genotype, genetic variation, chemical, or environmental exposure) and a condition (a phenotype or disease), where the presence of the entity reduces or eliminates some or all aspects of the condition.</obo:IAO_0000115>
<obo:IAO_0000118>is preventative for condition</obo:IAO_0000118>
<rdfs:comment>Genetic variations can span any level of granularity from a full genome or genotype to an individual gene or sequence alteration. These variations can be represented at the physical level (DNA/RNA macromolecules or their parts, as in the ChEBI ontology and Molecular Sequence Ontology) or at the abstract level (generically dependent continuant sequence features that are carried by these macromolecules, as in the Sequence Ontology and Genotype Ontology). The causal relations in this hierarchy can be used in linking either physical or abstract genetic variations to phenotypes or diseases they cause or contribute to.
Environmental exposures include those imposed by natural environments, experimentally applied conditions, or clinical interventions.</rdfs:comment>
<rdfs:label xml:lang="en">ameliorates condition</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0003308 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0003308">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002610"/>
<obo:IAO_0000115>A relationship between an entity and a condition (phenotype or disease) with which it exhibits a statistical dependence relationship.</obo:IAO_0000115>
<rdfs:label xml:lang="en">correlated with condition</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0003309 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0003309">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0003305"/>
<obo:IAO_0000115>A relationship between an entity (e.g. a chemical, environmental exposure, or some form of genetic variation) and a condition (a phenotype or disease), where the presence of the entity worsens some or all aspects of the condition.</obo:IAO_0000115>
<rdfs:label xml:lang="en">exacerbates condition</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0003310 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0003310">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002410"/>
<obo:IAO_0000115>A relationship between a condition (a phenotype or disease) and an entity (e.g. a chemical, environmental exposure, or some form of genetic variation) where some or all aspects of the condition are reduced or eliminated by the presence of the entity.</obo:IAO_0000115>
<rdfs:label xml:lang="en">condition ameliorated by</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0003311 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0003311">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002410"/>
<obo:IAO_0000115>A relationship between a condition (a phenotype or disease) and an entity (e.g. a chemical, environmental exposure, or some form of genetic variation) where some or all aspects of the condition are worsened by the presence of the entity.</obo:IAO_0000115>
<rdfs:label xml:lang="en">condition exacerbated by</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0008501 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0008501">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002440"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0008502"/>
<obo:IAO_0000115>An interaction relationship wherein a plant or algae is living on the outside surface of another plant.</obo:IAO_0000115>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Epiphyte</obo:IAO_0000119>
<rdfs:label>epiphyte of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0008502 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0008502">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002440"/>
<obo:IAO_0000115>inverse of epiphyte of</obo:IAO_0000115>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/RO_0002259"/>
<rdfs:label>has epiphyte</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0008503 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0008503">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002444"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0008504"/>
<obo:IAO_0000115>A sub-relation of parasite of in which a parasite steals resources from another organism, usually food or nest material</obo:IAO_0000115>
<obo:IAO_0000119>https://en.wikipedia.org/wiki/Kleptoparasitism</obo:IAO_0000119>
<rdfs:label>kleptoparasite of</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0008504 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0008504">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002445"/>
<obo:IAO_0000115>inverse of kleptoparasite of</obo:IAO_0000115>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/RO_0002259"/>
<rdfs:label>kleptoparasitized by</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0008505 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0008505">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002321"/>
<obo:IAO_0000115>An interaction relationship wherein one organism creates a structure or environment that is lived in by another organism.</obo:IAO_0000115>
<rdfs:label>creates habitat for</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0008506 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0008506">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002321"/>
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#SymmetricProperty"/>
<obo:IAO_0000115>An interaction relationship describing organisms that often occur together at the same time and space or in the same environment.</obo:IAO_0000115>
<rdfs:label>co-occurs</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0008507 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0008507">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002618"/>
<owl:inverseOf rdf:resource="http://purl.obolibrary.org/obo/RO_0008508"/>
<obo:IAO_0000115>An interaction relationship in which organism a lays eggs on the outside surface of organism b. Organism b is neither helped nor harmed in the process of egg laying or incubation.</obo:IAO_0000115>
<rdfs:label>lays eggs on</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0008508 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0008508">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002619"/>
<obo:IAO_0000115>An interaction relationship in which organism a lays eggs on the outside surface of organism b. Organism b is neither helped nor harmed in the process of egg laying or incubation.</obo:IAO_0000115>
<rdfs:label>has eggs laid on by</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0009001 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0009001">
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#IrreflexiveProperty"/>
<obo:IAO_0000112 xml:lang="en">muffin 'has substance added' some 'baking soda'</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000428"/>
<obo:IAO_0000115 xml:lang="en">"has substance added" is a relation existing between a (physical) entity and a substance in which the entity has had the substance added to it at some point in time.</obo:IAO_0000115>
<obo:IAO_0000116 xml:lang="en">The relation X 'has substance added' some Y doesn't imply that X still has Y in any detectable fashion subsequent to the addition. Water in dehydrated food or ice cubes are examples, as is food that undergoes chemical transformation. This definition should encompass recipe ingredients.</obo:IAO_0000116>
<obo:IAO_0000117>Damion Dooley</obo:IAO_0000117>
<rdfs:label xml:lang="en">has substance added</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0009002 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0009002">
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#IrreflexiveProperty"/>
<obo:IAO_0000112 xml:lang="en">'egg white' 'has substance removed' some 'egg yolk'</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000428"/>
<obo:IAO_0000115 xml:lang="en">"has substance removed" is a relation existing between two physical entities in which the first entity has had the second entity (a substance) removed from it at some point in time.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Damion Dooley</obo:IAO_0000117>
<rdfs:label xml:lang="en">has substance removed</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0009003 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0009003">
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#IrreflexiveProperty"/>
<obo:IAO_0000112 xml:lang="en">sardines 'immersed in' some 'oil and mustard'</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000428"/>
<obo:IAO_0000115 xml:lang="en">"immersed in" is a relation between a (physical) entity and a fluid substance in which the entity is wholely or substantially surrounded by the substance.</obo:IAO_0000115>
<obo:IAO_0000117>Damion Dooley</obo:IAO_0000117>
<rdfs:label xml:lang="en">immersed in</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0009005 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0009005">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0009001"/>
<rdf:type rdf:resource="http://www.w3.org/2002/07/owl#IrreflexiveProperty"/>
<obo:IAO_0000112 xml:lang="en">bread 'has primary substance added' some 'flour'</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000428"/>
<obo:IAO_0000115 xml:lang="en">'has primary substance added' indicates that an entity has had the given substance added to it in a proportion greater than any other added substance.</obo:IAO_0000115>
<obo:IAO_0000117>Damion Dooley</obo:IAO_0000117>
<rdfs:label xml:lang="en">has primary substance added</rdfs:label>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0009501 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0009501">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002410"/>
<rdfs:domain rdf:resource="http://purl.obolibrary.org/obo/BFO_0000017"/>
<rdfs:range rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/BFO_0000054"/>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002404"/>
</owl:propertyChainAxiom>
<obo:IAO_0000112>A drought sensitivity trait that inheres in a whole plant is realized in a systemic response process in response to exposure to drought conditions.</obo:IAO_0000112>
<obo:IAO_0000112>Environmental polymorphism in butterflies: These butterflies have a 'responsivity to day length trait' that is realized in response to the duration of the day, and is realized in developmental processes that lead to increased or decreased pigmentation in the adult morph.</obo:IAO_0000112>
<obo:IAO_0000115>r 'realized in response to' s iff, r is a realizable (e.g. a plant trait such as responsivity to drought), s is an environmental stimulus (a process), and s directly causes the realization of r.</obo:IAO_0000115>
<dc:contributor>Austin Meier</dc:contributor>
<dc:contributor>Chris Mungall</dc:contributor>
<dc:contributor>David Osumi-Sutherland</dc:contributor>
<dc:contributor>Marie Angelique Laporte</dc:contributor>
<rdfs:label xml:lang="en">realized in response to</rdfs:label>
<rdfs:seeAlso rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://docs.google.com/document/d/1KWhZxVBhIPkV6_daHta0h6UyHbjY2eIrnON1WIRGgdY/edit</rdfs:seeAlso>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_HOM0000001 -->
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_HOM0000001">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002158"/>
</rdf:Description>
<!-- http://purl.obolibrary.org/obo/RO_HOM0000003 -->
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_HOM0000003">
<rdfs:subPropertyOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002320"/>
</rdf:Description>
<!-- http://www.w3.org/2002/07/owl#topObjectProperty -->
<owl:ObjectProperty rdf:about="http://www.w3.org/2002/07/owl#topObjectProperty"/>
<!--
///////////////////////////////////////////////////////////////////////////////////////
//
// Classes
//
///////////////////////////////////////////////////////////////////////////////////////
-->
<!-- http://purl.obolibrary.org/obo/CARO_0000003 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CARO_0000003">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CARO_0000006"/>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/caro.owl"/>
<rdfs:label xml:lang="en">anatomical structure</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CARO_0000006 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CARO_0000006">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/caro.owl"/>
<rdfs:label xml:lang="en">material anatomical entity</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CARO_0000007 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CARO_0000007">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000141"/>
<rdfs:label>immaterial anatomical entity</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CARO_0000011 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CARO_0000011">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CARO_0000006"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002577"/>
<rdfs:label>connected anatomical system</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CARO_0000014 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CARO_0000014">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CARO_0000003"/>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/caro.owl"/>
<obo:IAO_0000589>cell part (CARO)</obo:IAO_0000589>
<rdfs:label xml:lang="en">cell part</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CARO_0001000 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CARO_0001000">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CARO_0000003"/>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/caro.owl"/>
<rdfs:label xml:lang="en">multi-cell-part structure</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CARO_0001001 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CARO_0001001">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CARO_0001000"/>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/caro.owl"/>
<rdfs:label xml:lang="en">neuron projection bundle</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CARO_0010000 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CARO_0010000">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CARO_0000003"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002207"/>
<owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CARO_0010000"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/caro.owl"/>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">multicellular anatomical structure</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CL_0000000 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CL_0000000">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CARO_0000003"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002207"/>
<owl:allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000000"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
<rdfs:label xml:lang="en">cell</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/CL_0000540 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CL_0000540">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000000"/>
<obo:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
<rdfs:label xml:lang="en">neuron</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/ENVO_00000428 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/ENVO_00000428">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ENVO_01000254"/>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">biome</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/ENVO_01000254 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/ENVO_01000254">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002577"/>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">environmental system</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0003674 -->
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0003674">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
<obo:IAO_0000589>molecular process</obo:IAO_0000589>
</rdf:Description>
<!-- http://purl.obolibrary.org/obo/GO_0004842 -->
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0004842">
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002482"/>
<owl:hasSelf rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:hasSelf>
</owl:Restriction>
</rdfs:subClassOf>
</rdf:Description>
<!-- http://purl.obolibrary.org/obo/GO_0004872 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0004872">
<rdfs:label>receptor activity</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/GO_0005515 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0005515"/>
<!-- http://purl.obolibrary.org/obo/GO_0005634 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0005634"/>
<!-- http://purl.obolibrary.org/obo/GO_0016301 -->
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0016301">
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002481"/>
<owl:hasSelf rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:hasSelf>
</owl:Restriction>
</rdfs:subClassOf>
</rdf:Description>
<!-- http://purl.obolibrary.org/obo/GO_0044403 -->
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0044403">
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002465"/>
<owl:hasSelf rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:hasSelf>
</owl:Restriction>
</rdfs:subClassOf>
</rdf:Description>
<!-- http://purl.obolibrary.org/obo/GO_0048018 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0048018"/>
<!-- http://purl.obolibrary.org/obo/GO_0072519 -->
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0072519">
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002468"/>
<owl:hasSelf rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:hasSelf>
</owl:Restriction>
</rdfs:subClassOf>
</rdf:Description>
<!-- http://purl.obolibrary.org/obo/GO_0085030 -->
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0085030">
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002467"/>
<owl:hasSelf rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:hasSelf>
</owl:Restriction>
</rdfs:subClassOf>
</rdf:Description>
<!-- http://purl.obolibrary.org/obo/GO_0085031 -->
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/GO_0085031">
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002466"/>
<owl:hasSelf rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</owl:hasSelf>
</owl:Restriction>
</rdfs:subClassOf>
</rdf:Description>
<!-- http://purl.obolibrary.org/obo/PATO_0000001 -->
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/PATO_0000001">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000020"/>
<obo:IAO_0000589>quality (PATO)</obo:IAO_0000589>
</rdf:Description>
<!-- http://purl.obolibrary.org/obo/PATO_0000051 -->
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/PATO_0000051">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000019"/>
</rdf:Description>
<!-- http://purl.obolibrary.org/obo/PATO_0000052 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0000052">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0000051"/>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">shape</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0000402 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0000402">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0002009"/>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">branched</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/PATO_0001199 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0001199"/>
<!-- http://purl.obolibrary.org/obo/PATO_0002009 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/PATO_0002009">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/PATO_0000052"/>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">branchiness</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/RO_0002310 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/RO_0002310">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
<obo:IAO_0000112>An exposure event in which a human is exposed to particulate matter in the air. Here the exposure stimulus/stress is the particulate matter, the receptor is the airways and lungs of the human,</obo:IAO_0000112>
<obo:IAO_0000112 rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">An exposure event in which a plant is provided with fertilizer. The exposure receptor is the root system of the plant, the stimulus is the fertilizing chemical, the route is via the soil, possibly mediated by symbotic microbes.</obo:IAO_0000112>
<obo:IAO_0000115>A process occurring within or in the vicinity of an organism that exerts some causal influence on the organism via the interaction between an exposure stimulus and an exposure receptor. The exposure stimulus may be a process, material entity or condition (for example, lack of nutrients). The exposure receptor can be an organism, organism population or a part of an organism.</obo:IAO_0000115>
<obo:IAO_0000116>This class is intended as a grouping for various domain and species-specific exposure classes. The ExO class http://purl.obolibrary.org/obo/ExO_0000002 'exposure event' assumes that all exposures involve stressors, which limits the applicability of this class to 'positive' exposures, e.g. exposing a plant to beneficial growing conditions.</obo:IAO_0000116>
<dc:creator>Chris Mungall</dc:creator>
<oboInOwl:created_by rdf:datatype="http://www.w3.org/2001/XMLSchema#string">cjm</oboInOwl:created_by>
<oboInOwl:creation_date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2017-06-05T17:55:39Z</oboInOwl:creation_date>
<rdfs:label>exposure event or process</rdfs:label>
<rdfs:seeAlso rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://github.com/oborel/obo-relations/pull/173</rdfs:seeAlso>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/RO_0002532 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/RO_0002532">
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002524"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/RO_0002533"/>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000115>Any entity that is ordered in discrete units along a linear axis.</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<rdfs:label>sequentially ordered entity</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/RO_0002533 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/RO_0002533">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002532"/>
<obo:IAO_0000115>Any individual unit of a collection of like units arranged in a linear order</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000232>An individual unit can be a molecular entity such as a base pair, or an abstract entity, such as the abstraction of a base pair.</obo:IAO_0000232>
<rdfs:label>sequence atomic unit</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/RO_0002534 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/RO_0002534">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/RO_0002532"/>
<obo:IAO_0000115>Any entity that can be divided into parts such that each part is an atomical unit of a sequence</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000232>Sequence bearers can be molecular entities, such as a portion of a DNA molecule, or they can be abstract entities, such as an entity representing all human sonic hedgehog regions of the genome with a particular DNA sequence.</obo:IAO_0000232>
<rdfs:label>sequence bearer</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/RO_0002577 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/RO_0002577">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<obo:IAO_0000115>A material entity consisting of multiple components that are causally integrated.</obo:IAO_0000115>
<obo:IAO_0000116>May be replaced by a BFO class, as discussed in http://www.jbiomedsem.com/content/4/1/43</obo:IAO_0000116>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000119>http://www.jbiomedsem.com/content/4/1/43</obo:IAO_0000119>
<rdfs:label>system</rdfs:label>
</owl:Class>
<!--
///////////////////////////////////////////////////////////////////////////////////////
//
// Annotations
//
///////////////////////////////////////////////////////////////////////////////////////
-->
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000078">
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<rdfs:label xml:lang="en">curation status specification</rdfs:label>
</rdf:Description>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000122">
<rdfs:label xml:lang="en">ready for release</rdfs:label>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
</rdf:Description>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000125">
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<rdfs:label xml:lang="en">pending final vetting</rdfs:label>
</rdf:Description>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000225">
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<rdfs:label xml:lang="en">obsolescence reason specification</rdfs:label>
</rdf:Description>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0000428">
<rdfs:label xml:lang="en">requires discussion</rdfs:label>
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
</rdf:Description>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/IAO_0100001">
<obo:IAO_0000114 rdf:resource="http://purl.obolibrary.org/obo/IAO_0000125"/>
<rdfs:label xml:lang="en">term replaced by</rdfs:label>
</rdf:Description>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0000092">
<obo:IAO_0000115>inverse of has disposition</obo:IAO_0000115>
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/RO_0002259"/>
</rdf:Description>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0001000">
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
<obo:IAO_0000232>This relation is taken from the RO2005 version of RO. It may be obsoleted and replaced by relations with different definitions. See also the 'develops from' family of relations.</obo:IAO_0000232>
</rdf:Description>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0001001">
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
</rdf:Description>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002081">
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
</rdf:Description>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002083">
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
</rdf:Description>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002084">
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
</rdf:Description>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002086">
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
</rdf:Description>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002089">
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
</rdf:Description>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002091">
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
</rdf:Description>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/RO_0002093">
<oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/ro/subsets#ro-eco"/>
</rdf:Description>
<rdf:Description rdf:about="http://www.w3.org/2000/01/rdf-schema#isDefinedBy">
<obo:IAO_0000589>is defined by</obo:IAO_0000589>
</rdf:Description>
<owl:Axiom>
<owl:annotatedSource rdf:resource="http://www.w3.org/2000/01/rdf-schema#isDefinedBy"/>
<owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000589"/>
<owl:annotatedTarget>is defined by</owl:annotatedTarget>
<rdfs:comment>This is an experimental annotation</rdfs:comment>
</owl:Axiom>
<!--
///////////////////////////////////////////////////////////////////////////////////////
//
// General axioms
//
///////////////////////////////////////////////////////////////////////////////////////
-->
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002566"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/BFO_0000040"/>
<rdfs:subClassOf>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002418"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002215"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
<owl:someValuesFrom>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002418"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/BFO_0000015"/>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:someValuesFrom>
</owl:Restriction>
</owl:unionOf>
</owl:Class>
</rdfs:subClassOf>
</owl:Restriction>
<!--
///////////////////////////////////////////////////////////////////////////////////////
//
// Rules
//
///////////////////////////////////////////////////////////////////////////////////////
-->
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/ro.owl#z">
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#Variable"/>
</rdf:Description>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/ro.owl#y">
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#Variable"/>
</rdf:Description>
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/ro.owl#x">
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#Variable"/>
</rdf:Description>
<rdf:Description rdf:about="urn:swrl#y">
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#Variable"/>
</rdf:Description>
<rdf:Description rdf:about="urn:swrl#x">
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#Variable"/>
</rdf:Description>
<rdf:Description rdf:about="urn:swrl#z">
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#Variable"/>
</rdf:Description>
<rdf:Description rdf:about="urn:swrl#B">
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#Variable"/>
</rdf:Description>
<rdf:Description rdf:about="urn:swrl#C">
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#Variable"/>
</rdf:Description>
<rdf:Description rdf:about="urn:swrl#A">
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#Variable"/>
</rdf:Description>
<rdf:Description rdf:about="urn:swrl#D">
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#Variable"/>
</rdf:Description>
<rdf:Description rdf:about="urn:swrl#mf">
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#Variable"/>
</rdf:Description>
<rdf:Description rdf:about="urn:swrl#eff">
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#Variable"/>
</rdf:Description>
<rdf:Description rdf:about="urn:swrl#in">
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#Variable"/>
</rdf:Description>
<rdf:Description rdf:about="urn:swrl#mf2">
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#Variable"/>
</rdf:Description>
<rdf:Description>
<swrla:isRuleEnabled rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</swrla:isRuleEnabled>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MF(X)-directly_regulates->MF(Y)-enabled_by->GP(Z) => MF(Y)-has_input->GP(Y) e.g. if 'protein kinase activity'(X) directly_regulates 'protein binding activity (Y)and this is enabled by GP(Z) then X has_input Z</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">infer input from direct reg</rdfs:label>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#Imp"/>
<swrl:body>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#IndividualPropertyAtom"/>
<swrl:propertyPredicate rdf:resource="http://purl.obolibrary.org/obo/RO_0002327"/>
<swrl:argument1 rdf:resource="http://purl.obolibrary.org/obo/ro.owl#z"/>
<swrl:argument2 rdf:resource="http://purl.obolibrary.org/obo/ro.owl#y"/>
</rdf:Description>
</rdf:first>
<rdf:rest>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#IndividualPropertyAtom"/>
<swrl:propertyPredicate rdf:resource="http://purl.obolibrary.org/obo/RO_0002578"/>
<swrl:argument1 rdf:resource="http://purl.obolibrary.org/obo/ro.owl#x"/>
<swrl:argument2 rdf:resource="http://purl.obolibrary.org/obo/ro.owl#y"/>
</rdf:Description>
</rdf:first>
<rdf:rest>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#ClassAtom"/>
<swrl:classPredicate rdf:resource="http://purl.obolibrary.org/obo/GO_0003674"/>
<swrl:argument1 rdf:resource="http://purl.obolibrary.org/obo/ro.owl#x"/>
</rdf:Description>
</rdf:first>
<rdf:rest>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#ClassAtom"/>
<swrl:classPredicate rdf:resource="http://purl.obolibrary.org/obo/GO_0003674"/>
<swrl:argument1 rdf:resource="http://purl.obolibrary.org/obo/ro.owl#y"/>
</rdf:Description>
</rdf:first>
<rdf:rest rdf:resource="http://www.w3.org/1999/02/22-rdf-syntax-ns#nil"/>
</rdf:Description>
</rdf:rest>
</rdf:Description>
</rdf:rest>
</rdf:Description>
</rdf:rest>
</rdf:Description>
</swrl:body>
<swrl:head>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#IndividualPropertyAtom"/>
<swrl:propertyPredicate rdf:resource="http://purl.obolibrary.org/obo/RO_0002233"/>
<swrl:argument1 rdf:resource="http://purl.obolibrary.org/obo/ro.owl#x"/>
<swrl:argument2 rdf:resource="http://purl.obolibrary.org/obo/ro.owl#z"/>
</rdf:Description>
</rdf:first>
<rdf:rest rdf:resource="http://www.w3.org/1999/02/22-rdf-syntax-ns#nil"/>
</rdf:Description>
</swrl:head>
</rdf:Description>
<rdf:Description>
<rdfs:comment>GP(X)-enables->MF(Y)-has_part->MF(Z) => GP(X) enables MF(Z),
e.g. if GP X enables ATPase coupled transporter activity' and 'ATPase coupled transporter activity' has_part 'ATPase activity' then GP(X) enables 'ATPase activity'</rdfs:comment>
<rdfs:label>enabling an MF enables its parts</rdfs:label>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#Imp"/>
<swrl:body>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#ClassAtom"/>
<swrl:classPredicate rdf:resource="http://purl.obolibrary.org/obo/GO_0003674"/>
<swrl:argument1 rdf:resource="urn:swrl#y"/>
</rdf:Description>
</rdf:first>
<rdf:rest>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#IndividualPropertyAtom"/>
<swrl:propertyPredicate rdf:resource="http://purl.obolibrary.org/obo/RO_0002327"/>
<swrl:argument1 rdf:resource="urn:swrl#x"/>
<swrl:argument2 rdf:resource="urn:swrl#y"/>
</rdf:Description>
</rdf:first>
<rdf:rest>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#IndividualPropertyAtom"/>
<swrl:propertyPredicate rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<swrl:argument1 rdf:resource="urn:swrl#y"/>
<swrl:argument2 rdf:resource="urn:swrl#z"/>
</rdf:Description>
</rdf:first>
<rdf:rest rdf:resource="http://www.w3.org/1999/02/22-rdf-syntax-ns#nil"/>
</rdf:Description>
</rdf:rest>
</rdf:Description>
</rdf:rest>
</rdf:Description>
</swrl:body>
<swrl:head>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#IndividualPropertyAtom"/>
<swrl:propertyPredicate rdf:resource="http://purl.obolibrary.org/obo/RO_0002327"/>
<swrl:argument1 rdf:resource="urn:swrl#x"/>
<swrl:argument2 rdf:resource="urn:swrl#z"/>
</rdf:Description>
</rdf:first>
<rdf:rest rdf:resource="http://www.w3.org/1999/02/22-rdf-syntax-ns#nil"/>
</rdf:Description>
</swrl:head>
</rdf:Description>
<rdf:Description>
<swrla:isRuleEnabled rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</swrla:isRuleEnabled>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">GP(X)-enables->MF(Y)-part_of->BP(Z) => GP(X) involved_in BP(Z) e.g. if X enables 'protein kinase activity' and Y 'part of' 'signal tranduction' then X involved in 'signal transduction'</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">involved in BP</rdfs:label>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#Imp"/>
<swrl:body>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#ClassAtom"/>
<swrl:classPredicate rdf:resource="http://purl.obolibrary.org/obo/GO_0008150"/>
<swrl:argument1 rdf:resource="urn:swrl#z"/>
</rdf:Description>
</rdf:first>
<rdf:rest>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#IndividualPropertyAtom"/>
<swrl:propertyPredicate rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<swrl:argument1 rdf:resource="urn:swrl#y"/>
<swrl:argument2 rdf:resource="urn:swrl#z"/>
</rdf:Description>
</rdf:first>
<rdf:rest>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#IndividualPropertyAtom"/>
<swrl:propertyPredicate rdf:resource="http://purl.obolibrary.org/obo/RO_0002327"/>
<swrl:argument1 rdf:resource="urn:swrl#x"/>
<swrl:argument2 rdf:resource="urn:swrl#y"/>
</rdf:Description>
</rdf:first>
<rdf:rest rdf:resource="http://www.w3.org/1999/02/22-rdf-syntax-ns#nil"/>
</rdf:Description>
</rdf:rest>
</rdf:Description>
</rdf:rest>
</rdf:Description>
</swrl:body>
<swrl:head>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#IndividualPropertyAtom"/>
<swrl:propertyPredicate rdf:resource="http://purl.obolibrary.org/obo/RO_0002331"/>
<swrl:argument1 rdf:resource="urn:swrl#x"/>
<swrl:argument2 rdf:resource="urn:swrl#z"/>
</rdf:Description>
</rdf:first>
<rdf:rest rdf:resource="http://www.w3.org/1999/02/22-rdf-syntax-ns#nil"/>
</rdf:Description>
</swrl:head>
</rdf:Description>
<rdf:Description>
<rdfs:label>From ligand activity to has_ligand</rdfs:label>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#Imp"/>
<swrl:body>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#IndividualPropertyAtom"/>
<swrl:propertyPredicate rdf:resource="http://purl.obolibrary.org/obo/RO_0002327"/>
<swrl:argument1 rdf:resource="urn:swrl#y"/>
<swrl:argument2 rdf:resource="urn:swrl#z"/>
</rdf:Description>
</rdf:first>
<rdf:rest>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#IndividualPropertyAtom"/>
<swrl:propertyPredicate rdf:resource="http://purl.obolibrary.org/obo/RO_0002578"/>
<swrl:argument1 rdf:resource="urn:swrl#z"/>
<swrl:argument2 rdf:resource="urn:swrl#x"/>
</rdf:Description>
</rdf:first>
<rdf:rest>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#ClassAtom"/>
<swrl:classPredicate rdf:resource="http://purl.obolibrary.org/obo/GO_0048018"/>
<swrl:argument1 rdf:resource="urn:swrl#z"/>
</rdf:Description>
</rdf:first>
<rdf:rest rdf:resource="http://www.w3.org/1999/02/22-rdf-syntax-ns#nil"/>
</rdf:Description>
</rdf:rest>
</rdf:Description>
</rdf:rest>
</rdf:Description>
</swrl:body>
<swrl:head>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#IndividualPropertyAtom"/>
<swrl:propertyPredicate rdf:resource="http://purl.obolibrary.org/obo/RO_0002019"/>
<swrl:argument1 rdf:resource="urn:swrl#x"/>
<swrl:argument2 rdf:resource="urn:swrl#y"/>
</rdf:Description>
</rdf:first>
<rdf:rest rdf:resource="http://www.w3.org/1999/02/22-rdf-syntax-ns#nil"/>
</rdf:Description>
</swrl:head>
</rdf:Description>
<rdf:Description>
<rdfs:comment>This rule is dubious: added as a quick fix for expected inference in GO-CAM. The problem is most acute for transmembrane proteins, such as receptors or cell adhesion molecules, which have some subfunctions inside the cell (e.g. kinase activity) and some subfunctions outside (e.g. ligand binding). Correct annotation of where these functions occurs leads to incorrect inference about the location of the whole protein. This should probably be weakened to "... -> overlaps"</rdfs:comment>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#Imp"/>
<swrl:body>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#IndividualPropertyAtom"/>
<swrl:propertyPredicate rdf:resource="http://purl.obolibrary.org/obo/RO_0002327"/>
<swrl:argument1 rdf:resource="urn:swrl#x"/>
<swrl:argument2 rdf:resource="urn:swrl#y"/>
</rdf:Description>
</rdf:first>
<rdf:rest>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#IndividualPropertyAtom"/>
<swrl:propertyPredicate rdf:resource="http://purl.obolibrary.org/obo/BFO_0000066"/>
<swrl:argument1 rdf:resource="urn:swrl#y"/>
<swrl:argument2 rdf:resource="urn:swrl#z"/>
</rdf:Description>
</rdf:first>
<rdf:rest rdf:resource="http://www.w3.org/1999/02/22-rdf-syntax-ns#nil"/>
</rdf:Description>
</rdf:rest>
</rdf:Description>
</swrl:body>
<swrl:head>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#IndividualPropertyAtom"/>
<swrl:propertyPredicate rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
<swrl:argument1 rdf:resource="urn:swrl#x"/>
<swrl:argument2 rdf:resource="urn:swrl#z"/>
</rdf:Description>
</rdf:first>
<rdf:rest rdf:resource="http://www.w3.org/1999/02/22-rdf-syntax-ns#nil"/>
</rdf:Description>
</swrl:head>
</rdf:Description>
<rdf:Description>
<rdfs:comment>If a molecular function (X) has a regulatory subfunction, then any gene product which is an input to that subfunction has an activity that directly_regulates X. Note: this is intended for cases where the regaultory subfunction is protein binding, so it could be tightened with an additional clause to specify this.</rdfs:comment>
<rdfs:label>inferring direct reg edge from input to regulatory subfunction</rdfs:label>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#Imp"/>
<swrl:body>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#IndividualPropertyAtom"/>
<swrl:propertyPredicate rdf:resource="http://purl.obolibrary.org/obo/RO_0002352"/>
<swrl:argument1 rdf:resource="urn:swrl#B"/>
<swrl:argument2 rdf:resource="urn:swrl#C"/>
</rdf:Description>
</rdf:first>
<rdf:rest>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#IndividualPropertyAtom"/>
<swrl:propertyPredicate rdf:resource="http://purl.obolibrary.org/obo/RO_0002333"/>
<swrl:argument1 rdf:resource="urn:swrl#A"/>
<swrl:argument2 rdf:resource="urn:swrl#B"/>
</rdf:Description>
</rdf:first>
<rdf:rest>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#IndividualPropertyAtom"/>
<swrl:propertyPredicate rdf:resource="http://purl.obolibrary.org/obo/RO_0002013"/>
<swrl:argument1 rdf:resource="urn:swrl#D"/>
<swrl:argument2 rdf:resource="urn:swrl#C"/>
</rdf:Description>
</rdf:first>
<rdf:rest rdf:resource="http://www.w3.org/1999/02/22-rdf-syntax-ns#nil"/>
</rdf:Description>
</rdf:rest>
</rdf:Description>
</rdf:rest>
</rdf:Description>
</swrl:body>
<swrl:head>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#IndividualPropertyAtom"/>
<swrl:propertyPredicate rdf:resource="http://purl.obolibrary.org/obo/RO_0002578"/>
<swrl:argument1 rdf:resource="urn:swrl#A"/>
<swrl:argument2 rdf:resource="urn:swrl#D"/>
</rdf:Description>
</rdf:first>
<rdf:rest rdf:resource="http://www.w3.org/1999/02/22-rdf-syntax-ns#nil"/>
</rdf:Description>
</swrl:head>
</rdf:Description>
<rdf:Description>
<rdfs:label>inferring direct neg reg edge from input to regulatory subfunction</rdfs:label>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#Imp"/>
<swrl:body>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#IndividualPropertyAtom"/>
<swrl:propertyPredicate rdf:resource="http://purl.obolibrary.org/obo/RO_0002352"/>
<swrl:argument1 rdf:resource="urn:swrl#B"/>
<swrl:argument2 rdf:resource="urn:swrl#C"/>
</rdf:Description>
</rdf:first>
<rdf:rest>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#IndividualPropertyAtom"/>
<swrl:propertyPredicate rdf:resource="http://purl.obolibrary.org/obo/RO_0002333"/>
<swrl:argument1 rdf:resource="urn:swrl#A"/>
<swrl:argument2 rdf:resource="urn:swrl#B"/>
</rdf:Description>
</rdf:first>
<rdf:rest>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#IndividualPropertyAtom"/>
<swrl:propertyPredicate rdf:resource="http://purl.obolibrary.org/obo/RO_0002014"/>
<swrl:argument1 rdf:resource="urn:swrl#D"/>
<swrl:argument2 rdf:resource="urn:swrl#C"/>
</rdf:Description>
</rdf:first>
<rdf:rest rdf:resource="http://www.w3.org/1999/02/22-rdf-syntax-ns#nil"/>
</rdf:Description>
</rdf:rest>
</rdf:Description>
</rdf:rest>
</rdf:Description>
</swrl:body>
<swrl:head>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#IndividualPropertyAtom"/>
<swrl:propertyPredicate rdf:resource="http://purl.obolibrary.org/obo/RO_0002630"/>
<swrl:argument1 rdf:resource="urn:swrl#A"/>
<swrl:argument2 rdf:resource="urn:swrl#D"/>
</rdf:Description>
</rdf:first>
<rdf:rest rdf:resource="http://www.w3.org/1999/02/22-rdf-syntax-ns#nil"/>
</rdf:Description>
</swrl:head>
</rdf:Description>
<rdf:Description>
<rdfs:label>inferring direct positive reg edge from input to regulatory subfunction</rdfs:label>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#Imp"/>
<swrl:body>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#IndividualPropertyAtom"/>
<swrl:propertyPredicate rdf:resource="http://purl.obolibrary.org/obo/RO_0002352"/>
<swrl:argument1 rdf:resource="urn:swrl#B"/>
<swrl:argument2 rdf:resource="urn:swrl#C"/>
</rdf:Description>
</rdf:first>
<rdf:rest>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#IndividualPropertyAtom"/>
<swrl:propertyPredicate rdf:resource="http://purl.obolibrary.org/obo/RO_0002333"/>
<swrl:argument1 rdf:resource="urn:swrl#A"/>
<swrl:argument2 rdf:resource="urn:swrl#B"/>
</rdf:Description>
</rdf:first>
<rdf:rest>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#IndividualPropertyAtom"/>
<swrl:propertyPredicate rdf:resource="http://purl.obolibrary.org/obo/RO_0002015"/>
<swrl:argument1 rdf:resource="urn:swrl#D"/>
<swrl:argument2 rdf:resource="urn:swrl#C"/>
</rdf:Description>
</rdf:first>
<rdf:rest rdf:resource="http://www.w3.org/1999/02/22-rdf-syntax-ns#nil"/>
</rdf:Description>
</rdf:rest>
</rdf:Description>
</rdf:rest>
</rdf:Description>
</swrl:body>
<swrl:head>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#IndividualPropertyAtom"/>
<swrl:propertyPredicate rdf:resource="http://purl.obolibrary.org/obo/RO_0002629"/>
<swrl:argument1 rdf:resource="urn:swrl#A"/>
<swrl:argument2 rdf:resource="urn:swrl#D"/>
</rdf:Description>
</rdf:first>
<rdf:rest rdf:resource="http://www.w3.org/1999/02/22-rdf-syntax-ns#nil"/>
</rdf:Description>
</swrl:head>
</rdf:Description>
<rdf:Description>
<rdfs:label>From has_ligand to ligand activity</rdfs:label>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#Imp"/>
<swrl:body>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#IndividualPropertyAtom"/>
<swrl:propertyPredicate rdf:resource="http://purl.obolibrary.org/obo/RO_0002019"/>
<swrl:argument1 rdf:resource="urn:swrl#x"/>
<swrl:argument2 rdf:resource="urn:swrl#y"/>
</rdf:Description>
</rdf:first>
<rdf:rest>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#IndividualPropertyAtom"/>
<swrl:propertyPredicate rdf:resource="http://purl.obolibrary.org/obo/RO_0002327"/>
<swrl:argument1 rdf:resource="urn:swrl#y"/>
<swrl:argument2 rdf:resource="urn:swrl#z"/>
</rdf:Description>
</rdf:first>
<rdf:rest rdf:resource="http://www.w3.org/1999/02/22-rdf-syntax-ns#nil"/>
</rdf:Description>
</rdf:rest>
</rdf:Description>
</swrl:body>
<swrl:head>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#IndividualPropertyAtom"/>
<swrl:propertyPredicate rdf:resource="http://purl.obolibrary.org/obo/RO_0002578"/>
<swrl:argument1 rdf:resource="urn:swrl#z"/>
<swrl:argument2 rdf:resource="urn:swrl#x"/>
</rdf:Description>
</rdf:first>
<rdf:rest>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#ClassAtom"/>
<swrl:classPredicate rdf:resource="http://purl.obolibrary.org/obo/GO_0048018"/>
<swrl:argument1 rdf:resource="urn:swrl#z"/>
</rdf:Description>
</rdf:first>
<rdf:rest rdf:resource="http://www.w3.org/1999/02/22-rdf-syntax-ns#nil"/>
</rdf:Description>
</rdf:rest>
</rdf:Description>
</swrl:head>
</rdf:Description>
<rdf:Description>
<rdfs:label>effector input is compound function input</rdfs:label>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#Imp"/>
<swrl:body>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#IndividualPropertyAtom"/>
<swrl:propertyPredicate rdf:resource="http://purl.obolibrary.org/obo/RO_0002025"/>
<swrl:argument1 rdf:resource="urn:swrl#mf"/>
<swrl:argument2 rdf:resource="urn:swrl#eff"/>
</rdf:Description>
</rdf:first>
<rdf:rest>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#IndividualPropertyAtom"/>
<swrl:propertyPredicate rdf:resource="http://purl.obolibrary.org/obo/RO_0002233"/>
<swrl:argument1 rdf:resource="urn:swrl#eff"/>
<swrl:argument2 rdf:resource="urn:swrl#in"/>
</rdf:Description>
</rdf:first>
<rdf:rest rdf:resource="http://www.w3.org/1999/02/22-rdf-syntax-ns#nil"/>
</rdf:Description>
</rdf:rest>
</rdf:Description>
</swrl:body>
<swrl:head>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#IndividualPropertyAtom"/>
<swrl:propertyPredicate rdf:resource="http://purl.obolibrary.org/obo/RO_0002233"/>
<swrl:argument1 rdf:resource="urn:swrl#mf"/>
<swrl:argument2 rdf:resource="urn:swrl#in"/>
</rdf:Description>
</rdf:first>
<rdf:rest rdf:resource="http://www.w3.org/1999/02/22-rdf-syntax-ns#nil"/>
</rdf:Description>
</swrl:head>
</rdf:Description>
<rdf:Description>
<rdfs:label>Input of effector is input of its parent MF</rdfs:label>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#Imp"/>
<swrl:body>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#IndividualPropertyAtom"/>
<swrl:propertyPredicate rdf:resource="http://purl.obolibrary.org/obo/RO_0002025"/>
<swrl:argument1 rdf:resource="urn:swrl#mf"/>
<swrl:argument2 rdf:resource="urn:swrl#eff"/>
</rdf:Description>
</rdf:first>
<rdf:rest>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#IndividualPropertyAtom"/>
<swrl:propertyPredicate rdf:resource="http://purl.obolibrary.org/obo/RO_0002233"/>
<swrl:argument1 rdf:resource="urn:swrl#mf"/>
<swrl:argument2 rdf:resource="urn:swrl#in"/>
</rdf:Description>
</rdf:first>
<rdf:rest rdf:resource="http://www.w3.org/1999/02/22-rdf-syntax-ns#nil"/>
</rdf:Description>
</rdf:rest>
</rdf:Description>
</swrl:body>
<swrl:head>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#IndividualPropertyAtom"/>
<swrl:propertyPredicate rdf:resource="http://purl.obolibrary.org/obo/RO_0002233"/>
<swrl:argument1 rdf:resource="urn:swrl#eff"/>
<swrl:argument2 rdf:resource="urn:swrl#in"/>
</rdf:Description>
</rdf:first>
<rdf:rest rdf:resource="http://www.w3.org/1999/02/22-rdf-syntax-ns#nil"/>
</rdf:Description>
</swrl:head>
</rdf:Description>
<rdf:Description>
<rdfs:comment>if effector directly regulates X, its parent MF directly regulates X</rdfs:comment>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#Imp"/>
<swrl:body>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#IndividualPropertyAtom"/>
<swrl:propertyPredicate rdf:resource="http://purl.obolibrary.org/obo/RO_0002578"/>
<swrl:argument1 rdf:resource="urn:swrl#mf"/>
<swrl:argument2 rdf:resource="urn:swrl#mf2"/>
</rdf:Description>
</rdf:first>
<rdf:rest>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#IndividualPropertyAtom"/>
<swrl:propertyPredicate rdf:resource="http://purl.obolibrary.org/obo/RO_0002025"/>
<swrl:argument1 rdf:resource="urn:swrl#mf"/>
<swrl:argument2 rdf:resource="urn:swrl#eff"/>
</rdf:Description>
</rdf:first>
<rdf:rest rdf:resource="http://www.w3.org/1999/02/22-rdf-syntax-ns#nil"/>
</rdf:Description>
</rdf:rest>
</rdf:Description>
</swrl:body>
<swrl:head>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#IndividualPropertyAtom"/>
<swrl:propertyPredicate rdf:resource="http://purl.obolibrary.org/obo/RO_0002578"/>
<swrl:argument1 rdf:resource="urn:swrl#eff"/>
<swrl:argument2 rdf:resource="urn:swrl#mf2"/>
</rdf:Description>
</rdf:first>
<rdf:rest rdf:resource="http://www.w3.org/1999/02/22-rdf-syntax-ns#nil"/>
</rdf:Description>
</swrl:head>
</rdf:Description>
<rdf:Description>
<rdfs:comment>if effector directly positively regulates X, its parent MF directly positively regulates X</rdfs:comment>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#Imp"/>
<swrl:body>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
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<swrl:propertyPredicate rdf:resource="http://purl.obolibrary.org/obo/RO_0002025"/>
<swrl:argument1 rdf:resource="urn:swrl#mf"/>
<swrl:argument2 rdf:resource="urn:swrl#eff"/>
</rdf:Description>
</rdf:first>
<rdf:rest>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#IndividualPropertyAtom"/>
<swrl:propertyPredicate rdf:resource="http://purl.obolibrary.org/obo/RO_0002629"/>
<swrl:argument1 rdf:resource="urn:swrl#mf"/>
<swrl:argument2 rdf:resource="urn:swrl#mf2"/>
</rdf:Description>
</rdf:first>
<rdf:rest rdf:resource="http://www.w3.org/1999/02/22-rdf-syntax-ns#nil"/>
</rdf:Description>
</rdf:rest>
</rdf:Description>
</swrl:body>
<swrl:head>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#IndividualPropertyAtom"/>
<swrl:propertyPredicate rdf:resource="http://purl.obolibrary.org/obo/RO_0002629"/>
<swrl:argument1 rdf:resource="urn:swrl#eff"/>
<swrl:argument2 rdf:resource="urn:swrl#mf2"/>
</rdf:Description>
</rdf:first>
<rdf:rest rdf:resource="http://www.w3.org/1999/02/22-rdf-syntax-ns#nil"/>
</rdf:Description>
</swrl:head>
</rdf:Description>
<rdf:Description>
<rdfs:label>if effector directly negatively regulates X, its parent MF directly negatively regulates X</rdfs:label>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#Imp"/>
<swrl:body>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
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<swrl:propertyPredicate rdf:resource="http://purl.obolibrary.org/obo/RO_0002630"/>
<swrl:argument1 rdf:resource="urn:swrl#mf"/>
<swrl:argument2 rdf:resource="urn:swrl#mf2"/>
</rdf:Description>
</rdf:first>
<rdf:rest>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#IndividualPropertyAtom"/>
<swrl:propertyPredicate rdf:resource="http://purl.obolibrary.org/obo/RO_0002025"/>
<swrl:argument1 rdf:resource="urn:swrl#mf"/>
<swrl:argument2 rdf:resource="urn:swrl#eff"/>
</rdf:Description>
</rdf:first>
<rdf:rest rdf:resource="http://www.w3.org/1999/02/22-rdf-syntax-ns#nil"/>
</rdf:Description>
</rdf:rest>
</rdf:Description>
</swrl:body>
<swrl:head>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#IndividualPropertyAtom"/>
<swrl:propertyPredicate rdf:resource="http://purl.obolibrary.org/obo/RO_0002630"/>
<swrl:argument1 rdf:resource="urn:swrl#eff"/>
<swrl:argument2 rdf:resource="urn:swrl#mf2"/>
</rdf:Description>
</rdf:first>
<rdf:rest rdf:resource="http://www.w3.org/1999/02/22-rdf-syntax-ns#nil"/>
</rdf:Description>
</swrl:head>
</rdf:Description>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#Imp"/>
<swrl:body>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
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<swrl:propertyPredicate rdf:resource="http://purl.obolibrary.org/obo/RO_0002212"/>
<swrl:argument1 rdf:resource="urn:swrl#x"/>
<swrl:argument2 rdf:resource="urn:swrl#y"/>
</rdf:Description>
</rdf:first>
<rdf:rest>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#IndividualPropertyAtom"/>
<swrl:propertyPredicate rdf:resource="http://purl.obolibrary.org/obo/RO_0002213"/>
<swrl:argument1 rdf:resource="urn:swrl#y"/>
<swrl:argument2 rdf:resource="urn:swrl#z"/>
</rdf:Description>
</rdf:first>
<rdf:rest rdf:resource="http://www.w3.org/1999/02/22-rdf-syntax-ns#nil"/>
</rdf:Description>
</rdf:rest>
</rdf:Description>
</swrl:body>
<swrl:head>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
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<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#IndividualPropertyAtom"/>
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<swrl:argument1 rdf:resource="urn:swrl#x"/>
<swrl:argument2 rdf:resource="urn:swrl#z"/>
</rdf:Description>
</rdf:first>
<rdf:rest rdf:resource="http://www.w3.org/1999/02/22-rdf-syntax-ns#nil"/>
</rdf:Description>
</swrl:head>
</rdf:Description>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#Imp"/>
<swrl:body>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#IndividualPropertyAtom"/>
<swrl:propertyPredicate rdf:resource="http://purl.obolibrary.org/obo/RO_0002212"/>
<swrl:argument1 rdf:resource="urn:swrl#y"/>
<swrl:argument2 rdf:resource="urn:swrl#z"/>
</rdf:Description>
</rdf:first>
<rdf:rest>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
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<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#IndividualPropertyAtom"/>
<swrl:propertyPredicate rdf:resource="http://purl.obolibrary.org/obo/RO_0002213"/>
<swrl:argument1 rdf:resource="urn:swrl#x"/>
<swrl:argument2 rdf:resource="urn:swrl#y"/>
</rdf:Description>
</rdf:first>
<rdf:rest rdf:resource="http://www.w3.org/1999/02/22-rdf-syntax-ns#nil"/>
</rdf:Description>
</rdf:rest>
</rdf:Description>
</swrl:body>
<swrl:head>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#AtomList"/>
<rdf:first>
<rdf:Description>
<rdf:type rdf:resource="http://www.w3.org/2003/11/swrl#IndividualPropertyAtom"/>
<swrl:propertyPredicate rdf:resource="http://purl.obolibrary.org/obo/RO_0002212"/>
<swrl:argument1 rdf:resource="urn:swrl#x"/>
<swrl:argument2 rdf:resource="urn:swrl#z"/>
</rdf:Description>
</rdf:first>
<rdf:rest rdf:resource="http://www.w3.org/1999/02/22-rdf-syntax-ns#nil"/>
</rdf:Description>
</swrl:head>
</rdf:Description>
</rdf:RDF>
<!-- Generated by the OWL API (version 4.2.6) https://github.com/owlcs/owlapi -->
