R Under development (unstable) (2012-07-27 r60013) -- "Unsuffered Consequences"
Copyright (C) 2012 The R Foundation for Statistical Computing
ISBN 3-900051-07-0
Platform: i686-pc-linux-gnu (32-bit)

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> set.seed(1001)
> x <- runif(10)
> y <- 1000+x+rnorm(10,sd=0.1)
> d <- data.frame(x,y)
> 
> library(bbmle)
> ## warning
> m1 = mle2(y~dnorm(a+b*x,sd=exp(s)),start=list(a=900,b=1,s=log(0.1)),
+   control=list(parscale=c(1000,1,0.1)),data=d)
Warning message:
In fix_order(call$control$parscale, "parscale") :
  parscale not named: rearranging to match 'start'
> 
> m2 = mle2(y~dnorm(a+b*x,sd=exp(s)),start=list(a=900,b=1,s=log(0.1)),
+   control=list(parscale=c(b=1,a=1000,s=0.1)),data=d)
> 
> m3 = mle2(y~dnorm(a+b*x,sd=exp(s)),start=list(a=1,b=1,s=log(0.1)),
+   method="L-BFGS-B",lower=c(a=1100,b=2,s=-Inf),data=d)
Warning message:
In mle2(y ~ dnorm(a + b * x, sd = exp(s)), start = list(a = 1, b = 1,  :
  some parameters are on the boundary: variance-covariance calculations based on Hessian may be unreliable
> 
> ## warning
> m4 = mle2(y~dnorm(a+b*x,sd=exp(s)),start=list(b=1,a=1200,s=log(0.1)),
+   method="L-BFGS-B",lower=c(2,1100,0.1),data=d)
Warning messages:
1: In fix_order(call$lower, "lower bounds", -Inf) :
  lower bounds not named: rearranging to match 'start'
2: In mle2(y ~ dnorm(a + b * x, sd = exp(s)), start = list(b = 1, a = 1200,  :
  some parameters are on the boundary: variance-covariance calculations based on Hessian may be unreliable
> 
> c1 = coef(m3)[c("a","b","s")]
> c2 = coef(m4)[c("a","b","s")]
> if (!all(abs(c1-c2)<1e-7)) stop("mismatch")
> 
> proc.time()
   user  system elapsed 
  1.012   1.024   1.896