R Under development (unstable) (2017-10-27 r73634) -- "Unsuffered Consequences"
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> library(bbmle)
Loading required package: stats4
> old_opt <- options(digits=3)
> if (require(optimx)) {
+ x <- 0:10
+ y <- c(26, 17, 13, 12, 20, 5, 9, 8, 5, 4, 8)
+ d <- data.frame(x,y)
+ 
+ ## breaks, don't try this
+ ## optimx(fn=Lfn,par=c(15,6),method="Rvmmin")
+ 
+ suppressWarnings(m1 <- mle2(minuslogl=y~dpois(lambda=ymax/(1+x/xhalf)),
+      start=list(ymax=15,xhalf=6),data=d,
+      optimizer="optimx",
+            method=c("BFGS","Nelder-Mead","CG")))
+ 
+ ## FIXME!! fails (although not with an error, because
+ ##  errors are caught by profiling) due to npar now
+ ## being restricted to >1 in optimx 2012.05.24 ...
+ 
+ suppressWarnings(head(as.data.frame(profile(m1))))
+ detach("package:optimx")
+ }
Loading required package: optimx
> options(old_opt)
> 
> proc.time()
   user  system elapsed 
  5.852   0.188  13.617