Revision 01aef11a0cc0c7f897c9497126d2ce454108eff1 authored by Williamreay on 13 June 2020, 01:20:04 UTC, committed by GitHub on 13 June 2020, 01:20:04 UTC
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README.md
## Lung_function_drug_repurposing_manuscript
Scripts used in Reay et al. study Genomics informed drug repurposing candidates for lung function and their implications for viral infection
The following scripts are featured in this respository:
# Figures
Scripts used for figure generation
# g1000_mRNA_GEUVADIS_scripts
Scripts used to test the association between PES profiles and mRNA expression
# Hunter_cohort_scripts
Scripts used to process the HCS cohort genotype and phenotype data
# LCV_scripts
Scripts used to construct LCV models
# MR_scripts
Scripts utilised to perform two-sample Mendelian randomisation to investigate the relationship between fasting glucose and lung function
# PES scripts
Scripts utilised to identify candidate PES gene-sets and calculate pathway specific scores
# TWAS scripts
Scripts utilised to perform TWAS
Questions related to these scripts can be directed to William Reay (william.reay@uon.edu.au), whilst queries related to the manuscript can be sent to Professor Murray Cairns (murray.cairns@newcastle.edu.au).

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