Revision 6b9cee07bdce93e338e4b25e3c60aa19abbbc50e authored by Torsten Hothorn on 31 March 2009, 00:00:00 UTC, committed by Gabor Csardi on 31 March 2009, 00:00:00 UTC
1 parent 59aef90
alpha.Rd
\name{alpha}
\alias{alpha}
\docType{data}
\title{ Genetic Components of Alcoholism }
\description{
Levels of expressed alpha synuclein mRNA in three groups of allele lengths
of NACP-REP1.
}
\usage{data("alpha")}
\format{
A data frame with 97 observations on the following 2 variables.
\describe{
\item{\code{alength}}{allele length, a factor with levels \code{short},
\code{intermediate} and \code{long}.}
\item{\code{elevel}}{expression levels of alpha synuclein mRNA.}
}
}
\details{
Various studies have linked alcohol dependence phenotypes to chromosome 4.
One candidate gene is NACP (non-amyloid component of plaques),
coding for alpha synuclein. B\"onsch et al. (2005) found longer alleles of
NACP-REP1 in alcohol-dependent patients compared with healthy
controls and report that the allele lengths show some
association with levels of expressed alpha synuclein mRNA.
}
\source{
Dominikus B\"onsch, Thomas Lederer, Udo Reulbach, Torsten Hothorn,
Johannes Kornhuber \& Stefan Bleich (2005).
Joint Analysis of the NACP-REP1 Marker Within the Alpha
Synuclein Gene Concludes Association with Alcohol Dependence.
\emph{Human Molecular Genetics}, \bold{14}(7), 967--971.
Torsten Hothorn, Kurt Hornik, Mark A. van de Wiel \& Achim Zeileis (2006).
A Lego system for conditional inference, \emph{The American Statistician},
\bold{60}(3), 257--263.
}
\examples{
boxplot(elevel ~ alength, data = alpha)
kruskal_test(elevel ~ alength, data = alpha)
}
\keyword{datasets}
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